STRINGSTRING
Map1lc3b Map1lc3b UBE2J1 UBE2J1 PSMA3 PSMA3 POLR2A POLR2A FBXO7 FBXO7 LOC100564835 LOC100564835 PRKAR2B PRKAR2B UBE2G1 UBE2G1 CACYBP CACYBP RTN1 RTN1 Rad18 Rad18 AXIN1 AXIN1 CEBPB CEBPB NLK NLK HSPA9 HSPA9 LAPTM4B LAPTM4B smg5 smg5 UBXN7 UBXN7 TRAF5 TRAF5 cacul1 cacul1 HGS HGS UBE2J2 UBE2J2 HSPBP1 HSPBP1 LOC100566904 LOC100566904 Dio2 Dio2 AICDA AICDA GABARAPL1 GABARAPL1 BCL2 BCL2 RALA RALA RIPK1 RIPK1 STX8 STX8 LYN LYN SMAD7 SMAD7 SMAD2 SMAD2 ubc ubc isg15 isg15 sncaip sncaip LOC100553543 LOC100553543 H9GR88_ANOCA H9GR88_ANOCA PIAS4 PIAS4 LOC100562987 LOC100562987 H9GRS7_ANOCA H9GRS7_ANOCA TANK TANK UBA52 UBA52 BAG4 BAG4 H9GT23_ANOCA H9GT23_ANOCA LOC100557336 LOC100557336 LOC100567233 LOC100567233 H9GU76_ANOCA H9GU76_ANOCA FHIT FHIT UBE2A UBE2A LOC103282543 LOC103282543 SQSTM1 SQSTM1 G1KZ36_ANOCA G1KZ36_ANOCA G1KZ53_ANOCA G1KZ53_ANOCA TMBIM6 TMBIM6 SLC22A18 SLC22A18 LOC100563825 LOC100563825 FAM178B FAM178B lrpprc lrpprc JKAMP JKAMP UBE2T UBE2T SMAD5 SMAD5 prkacb prkacb MYOD1 MYOD1 TSG101 TSG101 ERLIN2 ERLIN2 TRAF3 TRAF3 CUL4A CUL4A TRIB2 TRIB2 SPOPL SPOPL UBXN1 UBXN1 PRKAR1B PRKAR1B CUL2 CUL2 BOK BOK PPARGC1A PPARGC1A FZD8 FZD8 txnip txnip PACRGL PACRGL ATF6 ATF6 GPI GPI CAMLG CAMLG AXIN2 AXIN2 SMC6 SMC6 CASP10 CASP10 UBE2L3 UBE2L3 RNF8 RNF8 LOC100558586 LOC100558586 nfkbia nfkbia ANAPC2 ANAPC2 PAX6 PAX6 UBE2B UBE2B NAE1 NAE1 PSMD1 PSMD1 FZD4 FZD4 CASC3 CASC3 FBXW7 FBXW7 SCAMP3 SCAMP3 RTN3 RTN3 MFHAS1 MFHAS1 Park2 Park2 SYT11 SYT11 UBASH3A UBASH3A WRAP53 WRAP53 H9G7A9_ANOCA H9G7A9_ANOCA rps27a rps27a PACRG PACRG map1lc3c map1lc3c ARRDC1 ARRDC1 DBT DBT RB1 RB1 NDUFS2 NDUFS2 FBXW9 FBXW9 DDRGK1 DDRGK1 rnf31 rnf31 slf2 slf2 RALB RALB FANCL FANCL AMBRA1 AMBRA1 HSPA5 HSPA5 CUL3 CUL3 WBP1L WBP1L SPART SPART USP13 USP13 LOC100566691 LOC100566691 CCT2 CCT2 GLMN GLMN LOC100561099 LOC100561099 SPOP SPOP UBASH3B UBASH3B RANGAP1 RANGAP1 pa2g4 pa2g4 WFS1 WFS1 SNX9 SNX9 TRAF6 TRAF6 PRR5L PRR5L SUMO1 SUMO1 LOC100561878 LOC100561878 STAM STAM Det1 Det1 HM13 HM13 Nfatc2ip Nfatc2ip USP7 USP7 PRR7 PRR7 sumo2 sumo2 CUL5 CUL5 FAF2 FAF2 FAM162A FAM162A BAG2 BAG2 CDK5RAP3 CDK5RAP3 ARIH1 ARIH1 ELOB ELOB JUN JUN TRIP4 TRIP4 TRAF2 TRAF2 ube2l6 ube2l6 HLTF HLTF FAF1 FAF1 SHPRH SHPRH Cacul1 Cacul1 LOC100559227 LOC100559227 GABARAPL2 GABARAPL2 MC4R MC4R MFN2 MFN2 TRIB3 TRIB3 SUMO3 SUMO3 CRK CRK aup1 aup1 YWHAZ YWHAZ VCL VCL LOC100551781 LOC100551781 ITCH ITCH MAP1LC3A MAP1LC3A DERL1 DERL1 ANKRA2 ANKRA2 LOC100566729 LOC100566729 PARP9 PARP9 DTX3L DTX3L XRCC5 XRCC5 LOC100556214 LOC100556214 Prkaca Prkaca SMAD6 SMAD6 SMAD3 SMAD3 LOC100559698 LOC100559698 LOC100567618 LOC100567618 TRIB1 TRIB1 EGR2 EGR2 H9GGH2_ANOCA H9GGH2_ANOCA BLZF1 BLZF1 BAG5 BAG5 LOC100560412 LOC100560412 CUL4B CUL4B rnf20 rnf20 PDLIM2 PDLIM2 UBE2K UBE2K TRIM37 TRIM37 H9GHU4_ANOCA H9GHU4_ANOCA RTN4 RTN4 RNF40 RNF40 PRKAR2A PRKAR2A LOC103279522 LOC103279522 PIAS2 PIAS2 BAG6 BAG6 DNM1L DNM1L Bid Bid OTUB1 OTUB1 SLF1 SLF1 PRKAR1A PRKAR1A USP19 USP19 brca1 brca1 H9GK63_ANOCA H9GK63_ANOCA YOD1 YOD1 cul1 cul1 ASB4 ASB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Map1lc3bUncharacterized protein. (152 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (317 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
FBXO7F-box protein 7. (513 aa)
LOC100564835E3 ubiquitin protein ligase. (252 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (432 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
CACYBPCalcyclin binding protein. (221 aa)
RTN1Reticulon. (743 aa)
Rad18SAP domain-containing protein. (143 aa)
AXIN1Axin 1. (865 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (683 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (282 aa)
smg5Uncharacterized protein. (383 aa)
UBXN7UBX domain-containing protein 7. (488 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
cacul1Cullin domain-containing protein; Belongs to the cullin family. (385 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (784 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (262 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (336 aa)
LOC100566904MATH domain-containing protein. (307 aa)
Dio2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (74 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
BCL2BCL2 apoptosis regulator. (170 aa)
RALARAS like proto-oncogene A. (206 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (699 aa)
STX8Syntaxin 8. (236 aa)
LYNTyrosine-protein kinase. (514 aa)
SMAD7SMAD family member 7. (222 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ubcUncharacterized protein. (381 aa)
isg15Uncharacterized protein. (156 aa)
sncaipSNCAIP_SNCA_bd domain-containing protein. (272 aa)
LOC100553543Uncharacterized protein. (173 aa)
H9GR88_ANOCAUncharacterized protein. (139 aa)
PIAS4Protein inhibitor of activated STAT 4. (212 aa)
LOC100562987Cullin domain-containing protein; Belongs to the cullin family. (271 aa)
H9GRS7_ANOCAUbiquitin-like domain-containing protein. (33 aa)
TANKTRAF family member associated NFKB activator. (480 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (69 aa)
BAG4BCL2 associated athanogene 4. (425 aa)
H9GT23_ANOCATRAF-type domain-containing protein. (60 aa)
LOC100557336Protein kinase domain-containing protein. (172 aa)
LOC100567233c-SKI_SMAD_bind domain-containing protein. (174 aa)
H9GU76_ANOCARING-type domain-containing protein. (130 aa)
FHITFragile histidine triad diadenosine triphosphatase. (114 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
LOC103282543Uncharacterized protein. (158 aa)
SQSTM1Sequestosome 1. (440 aa)
G1KZ36_ANOCACul7 domain-containing protein. (756 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (238 aa)
SLC22A18Solute carrier family 22 member 18. (432 aa)
LOC100563825BZIP domain-containing protein. (341 aa)
FAM178BFamily with sequence similarity 178 member B. (461 aa)
lrpprcPPR_long domain-containing protein. (1409 aa)
JKAMPJNK1/MAPK8 associated membrane protein. (311 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (235 aa)
SMAD5Mothers against decapentaplegic homolog. (476 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)
MYOD1Myogenic factor. (305 aa)
TSG101Tumor susceptibility 101. (392 aa)
ERLIN2ER lipid raft associated 2. (381 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (621 aa)
CUL4ACullin 4A; Belongs to the cullin family. (765 aa)
TRIB2Tribbles pseudokinase 2. (356 aa)
SPOPLSpeckle type BTB/POZ protein like. (392 aa)
UBXN1UBX domain protein 1. (198 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
CUL2Cullin 2; Belongs to the cullin family. (763 aa)
BOKBCL2 family apoptosis regulator BOK. (215 aa)
PPARGC1APPARG coactivator 1 alpha. (797 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa)
txnipArrestin_N domain-containing protein. (124 aa)
PACRGLParkin coregulated like. (253 aa)
ATF6Activating transcription factor 6. (647 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (297 aa)
AXIN2Axin 2. (842 aa)
SMC6Structural maintenance of chromosomes 6. (1117 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (528 aa)
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
LOC100558586Uncharacterized protein. (236 aa)
nfkbiaANK_REP_REGION domain-containing protein. (310 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (828 aa)
PAX6Paired box 6. (422 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
NAE1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (575 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (956 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
CASC3CASC3 exon junction complex subunit. (723 aa)
FBXW7F-box and WD repeat domain containing 7. (592 aa)
SCAMP3Secretory carrier-associated membrane protein. (348 aa)
RTN3Reticulon. (975 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (984 aa)
Park2RBR-type E3 ubiquitin transferase. (108 aa)
SYT11Synaptotagmin 11. (423 aa)
UBASH3AUbiquitin associated and SH3 domain containing A. (558 aa)
WRAP53WD repeat containing antisense to TP53. (383 aa)
H9G7A9_ANOCAUncharacterized protein. (197 aa)
rps27aUbiquitin-like domain-containing protein. (156 aa)
PACRGParkin coregulated. (251 aa)
map1lc3cMicrotubule associated protein 1 light chain 3 gamma. (141 aa)
ARRDC1Arrestin domain containing 1. (280 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (540 aa)
RB1RB transcriptional corepressor 1. (901 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2. (256 aa)
FBXW9F-box and WD repeat domain containing 9. (493 aa)
DDRGK1DDRGK domain containing 1. (287 aa)
rnf31Uncharacterized protein. (851 aa)
slf2Uncharacterized protein. (1187 aa)
RALBRAS like proto-oncogene B. (206 aa)
FANCLFA complementation group L. (420 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1297 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (655 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
WBP1LWW domain binding protein 1 like. (346 aa)
SPARTSpartin. (628 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (939 aa)
LOC100566691Uncharacterized protein. (132 aa)
CCT2Chaperonin containing TCP1 subunit 2. (534 aa)
GLMNGlomulin, FKBP associated protein. (592 aa)
LOC100561099Uncharacterized protein; Belongs to the cullin family. (2527 aa)
SPOPSpeckle type BTB/POZ protein. (374 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (598 aa)
RANGAP1Ran GTPase activating protein 1. (591 aa)
pa2g4Peptidase_M24 domain-containing protein. (394 aa)
WFS1Wolframin ER transmembrane glycoprotein. (808 aa)
SNX9Sorting nexin. (608 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (548 aa)
PRR5LProline rich 5 like. (366 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
LOC100561878Uncharacterized protein; Belongs to the cullin family. (983 aa)
STAMSignal transducing adaptor molecule. (542 aa)
Det1Uncharacterized protein. (564 aa)
HM13Uncharacterized protein. (245 aa)
Nfatc2ipUbiquitin-like domain-containing protein. (126 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1094 aa)
PRR7Proline rich 7, synaptic. (247 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
FAF2Fas associated factor family member 2. (446 aa)
FAM162AFamily with sequence similarity 162 member A. (160 aa)
BAG2BCL2 associated athanogene 2. (222 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (512 aa)
ARIH1RBR-type E3 ubiquitin transferase. (452 aa)
ELOBElongin B. (119 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
TRIP4Thyroid hormone receptor interactor 4. (642 aa)
TRAF2TNF receptor-associated factor. (432 aa)
ube2l6UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
HLTFHelicase like transcription factor. (1007 aa)
FAF1Fas associated factor 1. (653 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1598 aa)
Cacul1Cullin domain-containing protein; Belongs to the cullin family. (141 aa)
LOC100559227Reticulon. (190 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
MC4RMelanocortin 4 receptor. (312 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (480 aa)
TRIB3Tribbles pseudokinase 3. (258 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
CRKCRK proto-oncogene, adaptor protein. (228 aa)
aup1CUE domain-containing protein. (142 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
VCLVinculin. (1142 aa)
LOC100551781EST1_DNA_bind domain-containing protein. (484 aa)
ITCHE3 ubiquitin-protein ligase. (930 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (250 aa)
ANKRA2Ankyrin repeat family A member 2. (313 aa)
LOC100566729Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (672 aa)
PARP9Poly [ADP-ribose] polymerase. (803 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (759 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (729 aa)
LOC100556214Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
PrkacaUncharacterized protein. (172 aa)
SMAD6Mothers against decapentaplegic homolog. (417 aa)
SMAD3Mothers against decapentaplegic homolog. (383 aa)
LOC100559698Uncharacterized protein. (604 aa)
LOC100567618Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
TRIB1Tribbles pseudokinase 1. (355 aa)
EGR2Early growth response 2. (454 aa)
H9GGH2_ANOCAMATH domain-containing protein. (185 aa)
BLZF1Basic leucine zipper nuclear factor 1. (414 aa)
BAG5BCL2 associated athanogene 5. (450 aa)
LOC100560412Uncharacterized protein. (390 aa)
CUL4BCullin 4B; Belongs to the cullin family. (898 aa)
rnf20E3 ubiquitin protein ligase. (884 aa)
PDLIM2PDZ and LIM domain 2. (360 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
TRIM37Tripartite motif containing 37. (967 aa)
H9GHU4_ANOCAUncharacterized protein. (267 aa)
RTN4Reticulon. (975 aa)
RNF40E3 ubiquitin protein ligase. (1029 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (314 aa)
LOC103279522Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (223 aa)
PIAS2Protein inhibitor of activated STAT 2. (601 aa)
BAG6BCL2 associated athanogene 6. (1193 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (736 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (186 aa)
OTUB1Ubiquitin thioesterase. (273 aa)
SLF1SMC5-SMC6 complex localization factor 1. (938 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (380 aa)
USP19Ubiquitin specific peptidase 19. (1376 aa)
brca1Uncharacterized protein. (772 aa)
H9GK63_ANOCAUncharacterized protein. (304 aa)
YOD1YOD1 deubiquitinase. (310 aa)
cul1CULLIN_2 domain-containing protein; Belongs to the cullin family. (704 aa)
ASB4Ankyrin repeat and SOCS box containing 4. (394 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (12%) [HD]