(13 nodes) Nuclear pore nuclear basket network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	MCM3AP	Minichromosome maintenance complex component 3 associated protein. (1948 aa)
	NUP35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (723 aa)
	LOC107982271	Uncharacterized protein. (178 aa)
	NUP98	Nucleoporin 98. (1201 aa)
	LOC100567513	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (97 aa)
	eny2	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (96 aa)
	CETN3	Centrin 3. (167 aa)
	PCID2	PCI domain containing 2. (399 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2366 aa)
	RANBP2	RAN binding protein 2. (2819 aa)
	NUP153	Nucleoporin 153. (1427 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CETN3	LOC100567513	ENSACAP00000000116	ENSACAP00000015709	Centrin 3.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	0.917
CETN3	MCM3AP	ENSACAP00000000116	ENSACAP00000004933	Centrin 3.	Minichromosome maintenance complex component 3 associated protein.	0.997
CETN3	NUP153	ENSACAP00000000116	ENSACAP00000004070	Centrin 3.	Nucleoporin 153.	0.491
CETN3	PCID2	ENSACAP00000000116	ENSACAP00000000199	Centrin 3.	PCI domain containing 2.	0.776
CETN3	TPR	ENSACAP00000000116	ENSACAP00000001710	Centrin 3.	Translocated promoter region, nuclear basket protein.	0.477
CETN3	eny2	ENSACAP00000000116	ENSACAP00000021100	Centrin 3.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	0.917
LOC100567513	CETN3	ENSACAP00000015709	ENSACAP00000000116	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	Centrin 3.	0.917
LOC100567513	MCM3AP	ENSACAP00000015709	ENSACAP00000004933	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	Minichromosome maintenance complex component 3 associated protein.	0.919
LOC100567513	NUP153	ENSACAP00000015709	ENSACAP00000004070	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	Nucleoporin 153.	0.639
LOC100567513	PCID2	ENSACAP00000015709	ENSACAP00000000199	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	PCI domain containing 2.	0.803
LOC107982271	MAD2L1	ENSACAP00000013807	ENSACAP00000012938	Uncharacterized protein.	Mitotic arrest deficient 2 like 1.	0.550
LOC107982271	NUP153	ENSACAP00000013807	ENSACAP00000004070	Uncharacterized protein.	Nucleoporin 153.	0.952
LOC107982271	NUP35	ENSACAP00000013807	ENSACAP00000008531	Uncharacterized protein.	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	0.923
LOC107982271	NUP98	ENSACAP00000013807	ENSACAP00000013811	Uncharacterized protein.	Nucleoporin 98.	0.993
LOC107982271	RANBP2	ENSACAP00000013807	ENSACAP00000002048	Uncharacterized protein.	RAN binding protein 2.	0.998
LOC107982271	TPR	ENSACAP00000013807	ENSACAP00000001710	Uncharacterized protein.	Translocated promoter region, nuclear basket protein.	0.878
MAD1L1	MAD2L1	ENSACAP00000010345	ENSACAP00000012938	Mitotic arrest deficient 1 like 1.	Mitotic arrest deficient 2 like 1.	0.999
MAD1L1	TPR	ENSACAP00000010345	ENSACAP00000001710	Mitotic arrest deficient 1 like 1.	Translocated promoter region, nuclear basket protein.	0.655
MAD2L1	LOC107982271	ENSACAP00000012938	ENSACAP00000013807	Mitotic arrest deficient 2 like 1.	Uncharacterized protein.	0.550
MAD2L1	MAD1L1	ENSACAP00000012938	ENSACAP00000010345	Mitotic arrest deficient 2 like 1.	Mitotic arrest deficient 1 like 1.	0.999