STRINGSTRING
CHEK1 CHEK1 BRCC3 BRCC3 NEK11 NEK11 RAD9B RAD9B CDC6 CDC6 NAE1 NAE1 LOC100556408 LOC100556408 TIPIN TIPIN topbp1 topbp1 TAOK3 TAOK3 H9G988_ANOCA H9G988_ANOCA DONSON DONSON EME1 EME1 atm atm UIMC1 UIMC1 SDE2 SDE2 CDCA7 CDCA7 RFWD3 RFWD3 DTL DTL CDK5RAP3 CDK5RAP3 CASP2 CASP2 WAC WAC GTSE1 GTSE1 FANCD2 FANCD2 RAD9A RAD9A hus1 hus1 ORC1 ORC1 TICRR TICRR MFSD11 MFSD11 BABAM2 BABAM2 ZNF830 ZNF830 RAD17 RAD17 G1KJZ5_ANOCA G1KJZ5_ANOCA NBN NBN ABRAXAS1 ABRAXAS1 CDK1 CDK1 nop53 nop53 PRKDC PRKDC PLK1 PLK1 FOXN3 FOXN3 TAOK1 TAOK1 brca1 brca1 XPC XPC syf2 syf2 MSH2 MSH2 MRE11 MRE11 BLM BLM FBXO31 FBXO31 RINT1 RINT1 TAOK2 TAOK2 FOXO4 FOXO4 CCND1 CCND1 mrnip mrnip clspn clspn H9GQZ2_ANOCA H9GQZ2_ANOCA G1KVM7_ANOCA G1KVM7_ANOCA H9GRB7_ANOCA H9GRB7_ANOCA G1KVT4_ANOCA G1KVT4_ANOCA G1KWK2_ANOCA G1KWK2_ANOCA LOC100567826 LOC100567826 H9GTZ6_ANOCA H9GTZ6_ANOCA G1KY24_ANOCA G1KY24_ANOCA H9GUR8_ANOCA H9GUR8_ANOCA LOC103282543 LOC103282543 PIDD1 PIDD1 H9GVW7_ANOCA H9GVW7_ANOCA R4G943_ANOCA R4G943_ANOCA R4G9N3_ANOCA R4G9N3_ANOCA ENSACAP00000022017 ENSACAP00000022017 R4GAZ5_ANOCA R4GAZ5_ANOCA R4GCF9_ANOCA R4GCF9_ANOCA R4GCI0_ANOCA R4GCI0_ANOCA R4GCV3_ANOCA R4GCV3_ANOCA R4GDA8_ANOCA R4GDA8_ANOCA R4GDH7_ANOCA R4GDH7_ANOCA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (261 aa)
NEK11NIMA related kinase 11. (610 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (399 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
NAE1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (575 aa)
LOC100556408FAT domain-containing protein. (2448 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (246 aa)
topbp1Uncharacterized protein. (946 aa)
TAOK3TAO kinase 3. (898 aa)
H9G988_ANOCAUncharacterized protein. (230 aa)
DONSONDownstream neighbor of SON. (327 aa)
EME1Essential meiotic structure-specific endonuclease 1. (590 aa)
atmUncharacterized protein; Belongs to the PI3/PI4-kinase family. (423 aa)
UIMC1Ubiquitin interaction motif containing 1. (714 aa)
SDE2SDE2 telomere maintenance homolog. (362 aa)
CDCA7Cell division cycle associated 7. (420 aa)
RFWD3Ring finger and WD repeat domain 3. (701 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (709 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (512 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (446 aa)
WACWW domain containing adaptor with coiled-coil. (624 aa)
GTSE1G2 and S-phase expressed 1. (719 aa)
FANCD2FA complementation group D2. (1450 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (384 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (284 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (867 aa)
TICRRTOPBP1 interacting checkpoint and replication regulator. (1882 aa)
MFSD11Major facilitator superfamily domain containing 11. (396 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
ZNF830Zinc finger protein 830. (376 aa)
RAD17RAD17 checkpoint clamp loader component. (678 aa)
G1KJZ5_ANOCAUncharacterized protein. (266 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (761 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (404 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (313 aa)
nop53Uncharacterized protein. (294 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4100 aa)
PLK1Polo like kinase 1. (416 aa)
FOXN3Forkhead box N3. (495 aa)
TAOK1TAO kinase 1. (1012 aa)
brca1Uncharacterized protein. (772 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (960 aa)
syf2Uncharacterized protein. (204 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (953 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (710 aa)
BLMBLM RecQ like helicase. (1396 aa)
FBXO31F-box protein 31. (563 aa)
RINT1RAD50 interactor 1. (815 aa)
TAOK2TAO kinase 2. (1018 aa)
FOXO4Forkhead box O4. (539 aa)
CCND1Cyclin D1. (154 aa)
mrnipUncharacterized protein. (120 aa)
clspnUncharacterized protein. (283 aa)
H9GQZ2_ANOCAUncharacterized protein. (166 aa)
G1KVM7_ANOCAUncharacterized protein. (297 aa)
H9GRB7_ANOCAUncharacterized protein. (301 aa)
G1KVT4_ANOCAReverse transcriptase domain-containing protein. (399 aa)
G1KWK2_ANOCAReverse transcriptase domain-containing protein. (294 aa)
LOC100567826Uncharacterized protein. (730 aa)
H9GTZ6_ANOCAUncharacterized protein. (621 aa)
G1KY24_ANOCAReverse transcriptase domain-containing protein. (317 aa)
H9GUR8_ANOCASEA domain-containing protein. (648 aa)
LOC103282543Uncharacterized protein. (158 aa)
PIDD1P53-induced death domain protein 1. (885 aa)
H9GVW7_ANOCAReverse transcriptase domain-containing protein. (356 aa)
R4G943_ANOCAReverse transcriptase domain-containing protein. (305 aa)
R4G9N3_ANOCAReverse transcriptase domain-containing protein. (295 aa)
ENSACAP00000022017annotation not available (305 aa)
R4GAZ5_ANOCAReverse transcriptase domain-containing protein. (767 aa)
R4GCF9_ANOCAReverse transcriptase domain-containing protein. (771 aa)
R4GCI0_ANOCAReverse transcriptase domain-containing protein. (300 aa)
R4GCV3_ANOCAReverse transcriptase domain-containing protein. (933 aa)
R4GDA8_ANOCAReverse transcriptase domain-containing protein. (1252 aa)
R4GDH7_ANOCAUncharacterized protein. (271 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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