(22 nodes) Face development network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LEF1	Lymphoid enhancer binding factor 1. (403 aa)
	CSRNP1	Cysteine and serine rich nuclear protein 1. (585 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (510 aa)
	PAX9	Paired box 9. (210 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	RAB3GAP1	RAB3 GTPase activating protein catalytic subunit 1. (980 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (411 aa)
	SRF	Serum response factor. (474 aa)
	EP300	E1A binding protein p300. (2484 aa)
	DKK1	Dickkopf WNT signaling pathway inhibitor 1. (238 aa)
	ankrd11	ANK_REP_REGION domain-containing protein. (2710 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
	DLX5	Distal-less homeobox 5. (293 aa)
	CRISPLD2	Cysteine rich secretory protein LCCL domain containing 2. (506 aa)
	CRISPLD1	Cysteine rich secretory protein LCCL domain containing 1. (503 aa)
	ZFAND5	Zinc finger AN1-type containing 5. (212 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (807 aa)
	MSX1	Msh homeobox 1. (281 aa)
	HOXB3	Homeobox B3. (416 aa)
	BBS4	Bardet-Biedl syndrome 4. (525 aa)
	NIPBL	Nipped-B protein. (2777 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (562 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSRNP1	MSX1	ENSACAP00000009555	ENSACAP00000010822	Cysteine and serine rich nuclear protein 1.	Msh homeobox 1.	0.558
DKK1	LEF1	ENSACAP00000005466	ENSACAP00000007988	Dickkopf WNT signaling pathway inhibitor 1.	Lymphoid enhancer binding factor 1.	0.640
DLX5	EDNRA	ENSACAP00000014450	ENSACAP00000003812	Distal-less homeobox 5.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.541
DLX5	PAX9	ENSACAP00000014450	ENSACAP00000001413	Distal-less homeobox 5.	Paired box 9.	0.439
EDNRA	DLX5	ENSACAP00000003812	ENSACAP00000014450	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Distal-less homeobox 5.	0.541
EP300	LEF1	ENSACAP00000005074	ENSACAP00000007988	E1A binding protein p300.	Lymphoid enhancer binding factor 1.	0.973
EP300	TGFB1	ENSACAP00000005074	ENSACAP00000018581	E1A binding protein p300.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.563
LEF1	DKK1	ENSACAP00000007988	ENSACAP00000005466	Lymphoid enhancer binding factor 1.	Dickkopf WNT signaling pathway inhibitor 1.	0.640
LEF1	EP300	ENSACAP00000007988	ENSACAP00000005074	Lymphoid enhancer binding factor 1.	E1A binding protein p300.	0.973
LEF1	MSX1	ENSACAP00000007988	ENSACAP00000010822	Lymphoid enhancer binding factor 1.	Msh homeobox 1.	0.632
LEF1	PAX9	ENSACAP00000007988	ENSACAP00000001413	Lymphoid enhancer binding factor 1.	Paired box 9.	0.434
MSX1	CSRNP1	ENSACAP00000010822	ENSACAP00000009555	Msh homeobox 1.	Cysteine and serine rich nuclear protein 1.	0.558
MSX1	LEF1	ENSACAP00000010822	ENSACAP00000007988	Msh homeobox 1.	Lymphoid enhancer binding factor 1.	0.632
MSX1	PAX9	ENSACAP00000010822	ENSACAP00000001413	Msh homeobox 1.	Paired box 9.	0.847
PAX9	DLX5	ENSACAP00000001413	ENSACAP00000014450	Paired box 9.	Distal-less homeobox 5.	0.439
PAX9	LEF1	ENSACAP00000001413	ENSACAP00000007988	Paired box 9.	Lymphoid enhancer binding factor 1.	0.434
PAX9	MSX1	ENSACAP00000001413	ENSACAP00000010822	Paired box 9.	Msh homeobox 1.	0.847
TGFB1	EP300	ENSACAP00000018581	ENSACAP00000005074	Transforming growth factor beta; Belongs to the TGF-beta family.	E1A binding protein p300.	0.563