35 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (502 aa)
	TM7SF3	Transmembrane 7 superfamily member 3. (548 aa)
	blk	Tyrosine-protein kinase. (448 aa)
	psmd9	PDZ domain-containing protein. (216 aa)
	CAPN10	Calpain 10; Belongs to the peptidase C2 family. (680 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1227 aa)
	SIRT6	Sirtuin 6. (176 aa)
	CRH	Corticotropin releasing hormone. (202 aa)
	AIMP1	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (111 aa)
	trh	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (243 aa)
	c2cd2l	SMP_C2CD2L domain-containing protein. (224 aa)
	FGG	Fibrinogen gamma chain. (436 aa)
	rph3al	Uncharacterized protein. (307 aa)
	FGB	Fibrinogen beta chain. (500 aa)
	SRI	Sorcin. (239 aa)
	AACS	Acetoacetyl-CoA synthetase. (667 aa)
	RFX6	Regulatory factor X6. (865 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	FFAR1	Free fatty acid receptor 1. (293 aa)
	MPC2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (125 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (460 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (172 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1415 aa)
	PLA2G6	Phospholipase A2 group VI. (663 aa)
	LOC100568265	Uncharacterized protein. (84 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
	SELENOT	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (146 aa)
	ffar4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (368 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (435 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	C1QTNF12	C1q and TNF related 12. (153 aa)
	LRRC8A	Leucine rich repeat containing 8 VRAC subunit A. (810 aa)
	pdx1	Homeobox domain-containing protein. (279 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (836 aa)
	TNFSF11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1	CRH	ENSACAP00000008538	ENSACAP00000016393	Adenylate cyclase activating polypeptide 1.	Corticotropin releasing hormone.	0.481
ADCYAP1	GHRHR	ENSACAP00000008538	ENSACAP00000005977	Adenylate cyclase activating polypeptide 1.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.780
AIMP1	LOC100568265	ENSACAP00000021668	ENSACAP00000008162	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1.	Uncharacterized protein.	0.900
CAPN10	SRI	ENSACAP00000011043	ENSACAP00000015702	Calpain 10; Belongs to the peptidase C2 family.	Sorcin.	0.415
CFTR	psmd9	ENSACAP00000007874	ENSACAP00000011138	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	PDZ domain-containing protein.	0.418
CRH	ADCYAP1	ENSACAP00000016393	ENSACAP00000008538	Corticotropin releasing hormone.	Adenylate cyclase activating polypeptide 1.	0.481
CRH	GHRHR	ENSACAP00000016393	ENSACAP00000005977	Corticotropin releasing hormone.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.615
CRH	trh	ENSACAP00000016393	ENSACAP00000023094	Corticotropin releasing hormone.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.773
FFAR1	ffar4	ENSACAP00000010076	ENSACAP00000006875	Free fatty acid receptor 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.592
FGB	FGG	ENSACAP00000015416	ENSACAP00000015388	Fibrinogen beta chain.	Fibrinogen gamma chain.	0.999
FGG	FGB	ENSACAP00000015388	ENSACAP00000015416	Fibrinogen gamma chain.	Fibrinogen beta chain.	0.999
GHRHR	ADCYAP1	ENSACAP00000005977	ENSACAP00000008538	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Adenylate cyclase activating polypeptide 1.	0.780
GHRHR	CRH	ENSACAP00000005977	ENSACAP00000016393	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Corticotropin releasing hormone.	0.615
LOC100568265	AIMP1	ENSACAP00000008162	ENSACAP00000021668	Uncharacterized protein.	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1.	0.900
SRI	CAPN10	ENSACAP00000015702	ENSACAP00000011043	Sorcin.	Calpain 10; Belongs to the peptidase C2 family.	0.415
ffar4	FFAR1	ENSACAP00000006875	ENSACAP00000010076	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Free fatty acid receptor 1.	0.592
psmd9	CFTR	ENSACAP00000011138	ENSACAP00000007874	PDZ domain-containing protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.418
trh	CRH	ENSACAP00000023094	ENSACAP00000016393	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	Corticotropin releasing hormone.	0.773