STRINGSTRING
SYNDIG1 SYNDIG1 GRID1 GRID1 LRFN2 LRFN2 EFNB2 EFNB2 RNF10 RNF10 CLSTN2 CLSTN2 NETO1 NETO1 LOC103282049 LOC103282049 LOC100562035 LOC100562035 synj2bp synj2bp PRR7 PRR7 NPTN NPTN Il1rapl1 Il1rapl1 GRM1 GRM1 LRFN1 LRFN1 CLSTN3 CLSTN3 NECTIN3 NECTIN3 ADCY1 ADCY1 GRIA1 GRIA1 LRFN5 LRFN5 GRIN2B GRIN2B PRRT1 PRRT1 LRRTM3 LRRTM3 GRIN3A GRIN3A Il1rapl2 Il1rapl2 CACNG5 CACNG5 ABHD17C ABHD17C ABHD17B ABHD17B lin7b lin7b Grid2 Grid2 G1KNX6_ANOCA G1KNX6_ANOCA LOC100566500 LOC100566500 PTPRO PTPRO ABHD17A ABHD17A LIN7A LIN7A Prrt2 Prrt2 GRM5 GRM5 RGS7BP RGS7BP LIN7C LIN7C ADAM22 ADAM22 LRRTM2 LRRTM2 CACNG2 CACNG2 GRIN2D GRIN2D CACNG7 CACNG7 GRIA2 GRIA2 DAGLA DAGLA CACNG8 CACNG8 G1KXW9_ANOCA G1KXW9_ANOCA CNKSR2 CNKSR2 G1KZ14_ANOCA G1KZ14_ANOCA R4GC49_ANOCA R4GC49_ANOCA GRIN2C GRIN2C CACNG4 CACNG4 SLITRK1 SLITRK1 GRIN2A GRIN2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYNDIG1Synapse differentiation inducing 1. (256 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (774 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (764 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (344 aa)
RNF10Ring finger protein 10. (797 aa)
CLSTN2Calsyntenin 2. (957 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
LOC103282049PDZ domain-containing protein. (160 aa)
LOC100562035Uncharacterized protein. (645 aa)
synj2bpPDZ domain-containing protein. (145 aa)
PRR7Proline rich 7, synaptic. (247 aa)
NPTNNeuroplastin. (402 aa)
Il1rapl1TIR domain-containing protein. (311 aa)
GRM1Glutamate metabotropic receptor 1. (931 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (459 aa)
CLSTN3Calsyntenin 3. (973 aa)
NECTIN3Nectin cell adhesion molecule 3. (511 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (875 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (771 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1500 aa)
PRRT1Proline rich transmembrane protein 1. (261 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (574 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1092 aa)
Il1rapl2TIR domain-containing protein. (292 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (271 aa)
ABHD17CAbhydrolase domain containing 17C. (305 aa)
ABHD17BAbhydrolase domain containing 17B. (288 aa)
lin7bProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (206 aa)
Grid2Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (250 aa)
G1KNX6_ANOCAUncharacterized protein. (224 aa)
LOC100566500Uncharacterized protein. (1099 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1218 aa)
ABHD17AAbhydrolase domain containing 17A. (308 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (216 aa)
Prrt2Uncharacterized protein. (251 aa)
GRM5Glutamate metabotropic receptor 5. (1202 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (259 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
ADAM22ADAM metallopeptidase domain 22. (923 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1252 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (281 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (885 aa)
DAGLADiacylglycerol lipase alpha. (1060 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (368 aa)
G1KXW9_ANOCAANF_receptor domain-containing protein. (200 aa)
CNKSR2Connector enhancer of kinase suppressor of Ras 2. (896 aa)
G1KZ14_ANOCAUncharacterized protein. (278 aa)
R4GC49_ANOCAUncharacterized protein. (61 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1387 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (308 aa)
SLITRK1SLIT and NTRK like family member 1. (701 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (684 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: medium (54%) [HD]