(46 nodes) GABA-ergic synapse network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (994 aa)
	NLGN1	Neuroligin 1. (513 aa)
	LRRTM2	Leucine rich repeat transmembrane neuronal 2. (516 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (5189 aa)
	nlgn3	COesterase domain-containing protein. (819 aa)
	GABRR1	Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (459 aa)
	CLSTN3	Calsyntenin 3. (973 aa)
	G1K858_ANOCA	Uncharacterized protein. (755 aa)
	IQSEC3	IQ motif and Sec7 domain 3. (1177 aa)
	SLITRK1	SLIT and NTRK like family member 1. (701 aa)
	H9G402_ANOCA	PH domain-containing protein. (213 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (946 aa)
	nlgn4x	Neuroligin 4. (834 aa)
	nlgn2	Neuroligin 2. (820 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (825 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (229 aa)
	GABRA2	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	C1QBP	Complement C1q binding protein. (284 aa)
	NPTN	Neuroplastin. (402 aa)
	DAG1	Dystroglycan 1. (888 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1218 aa)
	GABRA3	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (444 aa)
	CNTN5	Contactin 5. (1128 aa)
	SLC6A6	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (649 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1260 aa)
	H9GIF6_ANOCA	Uncharacterized protein. (221 aa)
	LOC100560507	AB hydrolase-1 domain-containing protein. (338 aa)
	LOC100557417	Uncharacterized protein. (334 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	H9GGK6_ANOCA	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1108 aa)
	CALB1	Calbindin 1. (262 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
	SLC6A1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
	LRFN5	Leucine rich repeat and fibronectin type III domain containing 5. (771 aa)
	atp2b2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1217 aa)
	ATP2B3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1237 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (460 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (522 aa)
	R4GDD2_ANOCA	AB hydrolase-1 domain-containing protein. (224 aa)
	LOC103278953	Peptidase S72 domain-containing protein. (1278 aa)
	ABHD6	AB hydrolase-1 domain-containing protein. (356 aa)
	H9GSV1_ANOCA	Uncharacterized protein. (124 aa)
	Erc1	FIP-RBD domain-containing protein. (334 aa)
	GABRR2	Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (516 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP2B3	ERC2	ENSACAP00000009397	ENSACAP00000005842	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	ELKS/RAB6-interacting/CAST family member 2.	0.583
CLSTN3	LRRTM1	ENSACAP00000007441	ENSACAP00000007623	Calsyntenin 3.	Leucine rich repeat transmembrane neuronal 1.	0.694
CTBP1	CTBP2	ENSACAP00000010097	ENSACAP00000014341	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.901
CTBP2	CTBP1	ENSACAP00000014341	ENSACAP00000010097	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.901
ERC2	ATP2B3	ENSACAP00000005842	ENSACAP00000009397	ELKS/RAB6-interacting/CAST family member 2.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.583
ERC2	Erc1	ENSACAP00000005842	ENSACAP00000019355	ELKS/RAB6-interacting/CAST family member 2.	FIP-RBD domain-containing protein.	0.899
ERC2	atp2b2	ENSACAP00000005842	ENSACAP00000009653	ELKS/RAB6-interacting/CAST family member 2.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.510
Erc1	ERC2	ENSACAP00000019355	ENSACAP00000005842	FIP-RBD domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.899
Erc1	G1K858_ANOCA	ENSACAP00000019355	ENSACAP00000000023	FIP-RBD domain-containing protein.	Uncharacterized protein.	0.900
Erc1	H9GSV1_ANOCA	ENSACAP00000019355	ENSACAP00000019688	FIP-RBD domain-containing protein.	Uncharacterized protein.	0.899
G1K858_ANOCA	Erc1	ENSACAP00000000023	ENSACAP00000019355	Uncharacterized protein.	FIP-RBD domain-containing protein.	0.900
GABBR1	GABBR2	ENSACAP00000010759	ENSACAP00000002178	Gamma-aminobutyric acid type B receptor subunit 1.	Gamma-aminobutyric acid type B receptor subunit 2.	0.900
GABBR2	GABBR1	ENSACAP00000002178	ENSACAP00000010759	Gamma-aminobutyric acid type B receptor subunit 2.	Gamma-aminobutyric acid type B receptor subunit 1.	0.900
GABRA2	GABRA3	ENSACAP00000006858	ENSACAP00000013709	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.748
GABRA2	GABRA5	ENSACAP00000006858	ENSACAP00000011346	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.774
GABRA2	GABRR1	ENSACAP00000006858	ENSACAP00000014406	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.740
GABRA2	GABRR2	ENSACAP00000006858	ENSACAP00000019030	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.742
GABRA2	H9G402_ANOCA	ENSACAP00000006858	ENSACAP00000000575	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	PH domain-containing protein.	0.609
GABRA2	H9GIF6_ANOCA	ENSACAP00000006858	ENSACAP00000011814	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein.	0.609
GABRA3	GABRA2	ENSACAP00000013709	ENSACAP00000006858	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.748