(28 nodes) Integral component of postsynaptic density membrane network (Anolis carolinensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	NETO1	Neuropilin and tolloid like 1. (533 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (344 aa)
	LRFN2	Leucine rich repeat and fibronectin type III domain containing 2. (764 aa)
	LRFN1	Leucine rich repeat and fibronectin type III domain containing 1. (459 aa)
	R4GC49_ANOCA	Uncharacterized protein. (61 aa)
	G1KXW9_ANOCA	ANF_receptor domain-containing protein. (200 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
	LRRTM2	Leucine rich repeat transmembrane neuronal 2. (516 aa)
	ADAM22	ADAM metallopeptidase domain 22. (923 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1218 aa)
	G1KNX6_ANOCA	Uncharacterized protein. (224 aa)
	Grid2	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (250 aa)
	Il1rapl2	TIR domain-containing protein. (292 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1092 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (574 aa)
	LRFN5	Leucine rich repeat and fibronectin type III domain containing 5. (771 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (308 aa)
	SLITRK1	SLIT and NTRK like family member 1. (701 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (684 aa)
	GRID1	Glutamate ionotropic receptor delta type subunit 1. (774 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (875 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	NECTIN3	Nectin cell adhesion molecule 3. (511 aa)
	CLSTN3	Calsyntenin 3. (973 aa)
	Il1rapl1	TIR domain-containing protein. (311 aa)
	NPTN	Neuroplastin. (402 aa)
	LOC100562035	Uncharacterized protein. (645 aa)
	CLSTN2	Calsyntenin 2. (957 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNG2	GRIA1	ENSACAP00000016014	ENSACAP00000009459	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Glutamate ionotropic receptor AMPA type subunit 1.	0.592
CACNG4	GRIA1	ENSACAP00000000189	ENSACAP00000009459	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Glutamate ionotropic receptor AMPA type subunit 1.	0.804
CACNG4	GRIN2A	ENSACAP00000000189	ENSACAP00000000881	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.584
G1KNX6_ANOCA	G1KXW9_ANOCA	ENSACAP00000013298	ENSACAP00000020424	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.900
G1KNX6_ANOCA	Grid2	ENSACAP00000013298	ENSACAP00000013292	Uncharacterized protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.916
G1KXW9_ANOCA	G1KNX6_ANOCA	ENSACAP00000020424	ENSACAP00000013298	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.900
G1KXW9_ANOCA	GRID1	ENSACAP00000020424	ENSACAP00000002069	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor delta type subunit 1.	0.899
G1KXW9_ANOCA	Grid2	ENSACAP00000020424	ENSACAP00000013292	ANF_receptor domain-containing protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.900
GRIA1	CACNG2	ENSACAP00000009459	ENSACAP00000016014	Glutamate ionotropic receptor AMPA type subunit 1.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.592
GRIA1	CACNG4	ENSACAP00000009459	ENSACAP00000000189	Glutamate ionotropic receptor AMPA type subunit 1.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.804
GRIA1	GRIN2A	ENSACAP00000009459	ENSACAP00000000881	Glutamate ionotropic receptor AMPA type subunit 1.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.779
GRIA1	LOC100562035	ENSACAP00000009459	ENSACAP00000004048	Glutamate ionotropic receptor AMPA type subunit 1.	Uncharacterized protein.	0.425
GRIA1	LRFN1	ENSACAP00000009459	ENSACAP00000023081	Glutamate ionotropic receptor AMPA type subunit 1.	Leucine rich repeat and fibronectin type III domain containing 1.	0.425
GRID1	G1KXW9_ANOCA	ENSACAP00000002069	ENSACAP00000020424	Glutamate ionotropic receptor delta type subunit 1.	ANF_receptor domain-containing protein.	0.899
GRIN2A	CACNG4	ENSACAP00000000881	ENSACAP00000000189	Glutamate ionotropic receptor NMDA type subunit 2A.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.584
GRIN2A	GRIA1	ENSACAP00000000881	ENSACAP00000009459	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor AMPA type subunit 1.	0.779
GRIN2A	GRIN3A	ENSACAP00000000881	ENSACAP00000010837	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.866
GRIN2A	LRFN2	ENSACAP00000000881	ENSACAP00000002423	Glutamate ionotropic receptor NMDA type subunit 2A.	Leucine rich repeat and fibronectin type III domain containing 2.	0.543
GRIN3A	GRIN2A	ENSACAP00000010837	ENSACAP00000000881	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.866
GRIN3A	LRFN2	ENSACAP00000010837	ENSACAP00000002423	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Leucine rich repeat and fibronectin type III domain containing 2.	0.434