30 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GFER	Sulfhydryl oxidase. (167 aa)
	BAG5	BCL2 associated athanogene 5. (450 aa)
	SIRT1	Sirtuin 1. (634 aa)
	OXR1	Oxidation resistance 1. (904 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1383 aa)
	H9GE80_ANOCA	Uncharacterized protein. (859 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	LRRK2	Leucine rich repeat kinase 2. (2540 aa)
	IL10	Interleukin 10. (174 aa)
	gpr37	G_PROTEIN_RECEP_F1_2 domain-containing protein. (173 aa)
	SLC7A11	Solute carrier family 7 member 11. (503 aa)
	NCOA7	Nuclear receptor coactivator 7. (821 aa)
	Park2	RBR-type E3 ubiquitin transferase. (108 aa)
	GPR37L1	G protein-coupled receptor 37 like 1. (526 aa)
	TSC1	TSC complex subunit 1. (1234 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (226 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CRYAB	Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family. (111 aa)
	ATF4	Activating transcription factor 4. (360 aa)
	REST	RE1 silencing transcription factor. (897 aa)
	NME5	NME/NM23 family member 5; Belongs to the NDK family. (211 aa)
	hspb6	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
	FBXO7	F-box protein 7. (513 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
	LOC100558405	Uncharacterized protein. (474 aa)
	LOC100558604	Uncharacterized protein. (507 aa)
	TRAP1	TNF receptor associated protein 1. (674 aa)
	DDR2	Discoidin domain receptor tyrosine kinase 2. (851 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (606 aa)
	RACK1	Receptor for activated C kinase 1. (317 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	NFE2L2	ENSACAP00000007417	ENSACAP00000011970	Activating transcription factor 4.	Nuclear factor, erythroid 2 like 2.	0.585
BAG5	LRRK2	ENSACAP00000010403	ENSACAP00000008041	BCL2 associated athanogene 5.	Leucine rich repeat kinase 2.	0.400
BAG5	Park2	ENSACAP00000010403	ENSACAP00000002831	BCL2 associated athanogene 5.	RBR-type E3 ubiquitin transferase.	0.466
BAG5	TRAP1	ENSACAP00000010403	ENSACAP00000012640	BCL2 associated athanogene 5.	TNF receptor associated protein 1.	0.434
CRYAB	TRAP1	ENSACAP00000006339	ENSACAP00000012640	Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.	TNF receptor associated protein 1.	0.442
CRYAB	TSC1	ENSACAP00000006339	ENSACAP00000004161	Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.	TSC complex subunit 1.	0.442
CRYAB	hspb6	ENSACAP00000006339	ENSACAP00000016379	Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.902
CTNNB1	LRRK2	ENSACAP00000004430	ENSACAP00000008041	Catenin beta 1.	Leucine rich repeat kinase 2.	0.410
CTNNB1	MET	ENSACAP00000004430	ENSACAP00000008564	Catenin beta 1.	MET proto-oncogene, receptor tyrosine kinase.	0.951
CTNNB1	SIRT1	ENSACAP00000004430	ENSACAP00000010385	Catenin beta 1.	Sirtuin 1.	0.562
CTNNB1	WNT1	ENSACAP00000004430	ENSACAP00000008042	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.785
FBXO7	Park2	ENSACAP00000014527	ENSACAP00000002831	F-box protein 7.	RBR-type E3 ubiquitin transferase.	0.699
GPR37L1	Park2	ENSACAP00000004067	ENSACAP00000002831	G protein-coupled receptor 37 like 1.	RBR-type E3 ubiquitin transferase.	0.434
HGF	IL10	ENSACAP00000013097	ENSACAP00000007764	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Interleukin 10.	0.459
HGF	MET	ENSACAP00000013097	ENSACAP00000008564	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	MET proto-oncogene, receptor tyrosine kinase.	0.997
IL10	HGF	ENSACAP00000007764	ENSACAP00000013097	Interleukin 10.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.459
LOC100558405	LOC100558604	ENSACAP00000013087	ENSACAP00000012908	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC100558405	SLC7A11	ENSACAP00000013087	ENSACAP00000001837	Uncharacterized protein.	Solute carrier family 7 member 11.	0.902
LOC100558604	LOC100558405	ENSACAP00000012908	ENSACAP00000013087	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC100558604	SLC7A11	ENSACAP00000012908	ENSACAP00000001837	Uncharacterized protein.	Solute carrier family 7 member 11.	0.902