STRINGSTRING
RBBP8 RBBP8 MRGBP MRGBP LOC100559058 LOC100559058 RIF1 RIF1 HELQ HELQ KMT5C KMT5C PIAS4 PIAS4 LOC103282487 LOC103282487 TIMELESS TIMELESS TRRAP TRRAP mrnip mrnip FOXM1 FOXM1 SPIRE2 SPIRE2 VPS72 VPS72 KMT5B KMT5B DMAP1 DMAP1 SLF1 SLF1 PNKP PNKP RUVBL2 RUVBL2 UBE2V2 UBE2V2 PRKDC PRKDC SPIDR SPIDR ERCC6 ERCC6 PARP3 PARP3 zcwpw1 zcwpw1 POGZ POGZ BCL7A BCL7A SIRT6 SIRT6 FANCB FANCB G1KJZ5_ANOCA G1KJZ5_ANOCA FH FH DTX3L DTX3L PARP9 PARP9 WDR48 WDR48 smchd1 smchd1 LOC100565669 LOC100565669 MGMT MGMT LOC100567827 LOC100567827 BCL7C BCL7C RUVBL1 RUVBL1 EPC1 EPC1 BRD8 BRD8 PARP1 PARP1 ACTL6A ACTL6A YEATS4 YEATS4 slf2 slf2 EPC2 EPC2 WRAP53 WRAP53 ARID2 ARID2 MBTD1 MBTD1 ACTR2 ACTR2 MMS19 MMS19 HDGFL2 HDGFL2 DDX11 DDX11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBBP8RB binding protein 8, endonuclease. (897 aa)
MRGBPMRG domain binding protein. (240 aa)
LOC100559058KIND domain-containing protein. (350 aa)
RIF1Replication timing regulatory factor 1. (2361 aa)
HELQHelicase, POLQ like. (1045 aa)
KMT5CLysine methyltransferase 5C. (472 aa)
PIAS4Protein inhibitor of activated STAT 4. (212 aa)
LOC103282487FAM35_C domain-containing protein. (146 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3856 aa)
mrnipUncharacterized protein. (120 aa)
FOXM1Forkhead box M1. (754 aa)
SPIRE2Spire type actin nucleation factor 2. (486 aa)
VPS72Vacuolar protein sorting 72 homolog. (329 aa)
KMT5BLysine methyltransferase 5B. (888 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (465 aa)
SLF1SMC5-SMC6 complex localization factor 1. (938 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (568 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (147 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4100 aa)
SPIDRScaffold protein involved in DNA repair. (990 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1440 aa)
PARP3Poly [ADP-ribose] polymerase. (542 aa)
zcwpw1Uncharacterized protein. (211 aa)
POGZPogo transposable element derived with ZNF domain. (1447 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (180 aa)
SIRT6Sirtuin 6. (176 aa)
FANCBFA complementation group B. (836 aa)
G1KJZ5_ANOCAUncharacterized protein. (266 aa)
FHFumarate hydratase. (467 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (759 aa)
PARP9Poly [ADP-ribose] polymerase. (803 aa)
WDR48WD repeat domain 48. (692 aa)
smchd1SMC hinge domain-containing protein. (508 aa)
LOC100565669Uncharacterized protein. (1422 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (118 aa)
LOC100567827Uncharacterized protein; Belongs to the actin family. (366 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (226 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
EPC1Enhancer of polycomb homolog. (742 aa)
BRD8Bromodomain containing 8. (1252 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
ACTL6AActin like 6A; Belongs to the actin family. (486 aa)
YEATS4YEATS domain containing 4. (227 aa)
slf2Uncharacterized protein. (1187 aa)
EPC2Enhancer of polycomb homolog. (806 aa)
WRAP53WD repeat containing antisense to TP53. (383 aa)
ARID2AT-rich interaction domain 2. (1840 aa)
MBTD1Mbt domain containing 1. (622 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (414 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (958 aa)
HDGFL2HDGF like 2. (420 aa)
DDX11DEAD/H-box helicase 11. (914 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (14%) [HD]