(53 nodes) Negative regulation of response to DNA damage stimulus network (Anolis carolinensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H9G6N6_ANOCA	Uncharacterized protein. (307 aa)
	TRIAP1	TP53 regulated inhibitor of apoptosis 1. (75 aa)
	FBH1	F-box DNA helicase 1. (1043 aa)
	hmga2	Uncharacterized protein. (72 aa)
	HELB	DNA helicase B. (1040 aa)
	H9GT41_ANOCA	Uncharacterized protein. (189 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1376 aa)
	LOC103282074	53-BP1_Tudor domain-containing protein. (1012 aa)
	FBXO5	F-box protein 5. (389 aa)
	TRIP12	Thyroid hormone receptor interactor 12. (1447 aa)
	xrcc1	Uncharacterized protein. (656 aa)
	TPT1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (172 aa)
	RECQL5	RecQ like helicase 5. (1015 aa)
	KLHL15	Kelch like family member 15. (604 aa)
	ZNF385A	Zinc finger protein 385A. (376 aa)
	PTTG1IP	PTTG1 interacting protein. (176 aa)
	THOC1	THO complex 1. (674 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (459 aa)
	rps3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	Ddias	Rep_fac-A_C domain-containing protein. (88 aa)
	ERCC6	ERCC excision repair 6, chromatin remodeling factor. (1440 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (842 aa)
	PARPBP	PARP1 binding protein. (442 aa)
	ATAD5	ATPase family AAA domain containing 5. (1748 aa)
	ercc1	Uncharacterized protein. (297 aa)
	bcl2l12	Uncharacterized protein. (363 aa)
	LOC100568010	Uncharacterized protein. (266 aa)
	H9GUR8_ANOCA	SEA domain-containing protein. (648 aa)
	RIF1	Replication timing regulatory factor 1. (2361 aa)
	LOC103282487	FAM35_C domain-containing protein. (146 aa)
	H9GQD0_ANOCA	Uncharacterized protein. (422 aa)
	H9GQ09_ANOCA	FAM35_C domain-containing protein. (867 aa)
	TRIM32	Tripartite motif containing 32. (653 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
	rmi2	Uncharacterized protein. (153 aa)
	CDKN2D	Cyclin dependent kinase inhibitor 2D. (163 aa)
	SNAI1	Snail family transcriptional repressor 1. (255 aa)
	CD74	CD74 molecule. (260 aa)
	RNF169	Ring finger protein 169. (592 aa)
	MARCHF7	Membrane associated ring-CH-type finger 7. (749 aa)
	OTUB1	Ubiquitin thioesterase. (273 aa)
	snai2	Uncharacterized protein. (268 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (242 aa)
	LOC100565669	Uncharacterized protein. (1422 aa)
	smchd1	SMC hinge domain-containing protein. (508 aa)
	THOC5	THO complex 5. (684 aa)
	UBR5	Ubiquitin protein ligase E3 component n-recognin 5. (2437 aa)
	OGG1	8-oxoguanine DNA glycosylase. (350 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	SIRT1	Sirtuin 1. (634 aa)
	FANCB	FA complementation group B. (836 aa)
	CLU	Clusterin; Belongs to the clusterin family. (467 aa)
	PPP1R10	Protein phosphatase 1 regulatory subunit 10. (888 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	ERCC4	ENSACAP00000019218	ENSACAP00000003517	ATPase family AAA domain containing 5.	ERCC excision repair 4, endonuclease catalytic subunit.	0.645
ATAD5	FBH1	ENSACAP00000019218	ENSACAP00000002866	ATPase family AAA domain containing 5.	F-box DNA helicase 1.	0.635
ATAD5	RECQL5	ENSACAP00000019218	ENSACAP00000006802	ATPase family AAA domain containing 5.	RecQ like helicase 5.	0.647
ATAD5	rmi2	ENSACAP00000019218	ENSACAP00000015697	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.503
ATAD5	xrcc1	ENSACAP00000019218	ENSACAP00000004173	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.483
CD74	FBXO5	ENSACAP00000014719	ENSACAP00000005498	CD74 molecule.	F-box protein 5.	0.551
CD74	TPT1	ENSACAP00000014719	ENSACAP00000006414	CD74 molecule.	Tumor protein, translationally-controlled 1; Belongs to the TCTP family.	0.867
CD74	rps3	ENSACAP00000014719	ENSACAP00000002108	CD74 molecule.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.995
ERCC4	ATAD5	ENSACAP00000003517	ENSACAP00000019218	ERCC excision repair 4, endonuclease catalytic subunit.	ATPase family AAA domain containing 5.	0.645
ERCC4	ERCC6	ENSACAP00000003517	ENSACAP00000011492	ERCC excision repair 4, endonuclease catalytic subunit.	ERCC excision repair 6, chromatin remodeling factor.	0.848
ERCC4	FANCB	ENSACAP00000003517	ENSACAP00000010423	ERCC excision repair 4, endonuclease catalytic subunit.	FA complementation group B.	0.921
ERCC4	FBH1	ENSACAP00000003517	ENSACAP00000002866	ERCC excision repair 4, endonuclease catalytic subunit.	F-box DNA helicase 1.	0.676
ERCC4	H9GT41_ANOCA	ENSACAP00000003517	ENSACAP00000019842	ERCC excision repair 4, endonuclease catalytic subunit.	Uncharacterized protein.	0.967
ERCC4	LOC103282074	ENSACAP00000003517	ENSACAP00000005073	ERCC excision repair 4, endonuclease catalytic subunit.	53-BP1_Tudor domain-containing protein.	0.735
ERCC4	OGG1	ENSACAP00000003517	ENSACAP00000009823	ERCC excision repair 4, endonuclease catalytic subunit.	8-oxoguanine DNA glycosylase.	0.447
ERCC4	RECQL5	ENSACAP00000003517	ENSACAP00000006802	ERCC excision repair 4, endonuclease catalytic subunit.	RecQ like helicase 5.	0.723
ERCC4	ercc1	ENSACAP00000003517	ENSACAP00000023179	ERCC excision repair 4, endonuclease catalytic subunit.	Uncharacterized protein.	0.980
ERCC4	rmi2	ENSACAP00000003517	ENSACAP00000015697	ERCC excision repair 4, endonuclease catalytic subunit.	Uncharacterized protein.	0.867
ERCC4	xrcc1	ENSACAP00000003517	ENSACAP00000004173	ERCC excision repair 4, endonuclease catalytic subunit.	Uncharacterized protein.	0.602
ERCC6	ERCC4	ENSACAP00000011492	ENSACAP00000003517	ERCC excision repair 6, chromatin remodeling factor.	ERCC excision repair 4, endonuclease catalytic subunit.	0.848