STRINGSTRING
H9GVW7_ANOCA H9GVW7_ANOCA R4G9N3_ANOCA R4G9N3_ANOCA FAM178B FAM178B ENSACAP00000022017 ENSACAP00000022017 MRGBP MRGBP R4GAZ5_ANOCA R4GAZ5_ANOCA R4GCF9_ANOCA R4GCF9_ANOCA R4GCI0_ANOCA R4GCI0_ANOCA R4GCV3_ANOCA R4GCV3_ANOCA G1KVT4_ANOCA G1KVT4_ANOCA PIAS4 PIAS4 LOC103282487 LOC103282487 H9GQ09_ANOCA H9GQ09_ANOCA NFRKB NFRKB EYA3 EYA3 BCLAF1 BCLAF1 EYA2 EYA2 TIMELESS TIMELESS RNF168 RNF168 TRRAP TRRAP PBK PBK mrnip mrnip TFPT TFPT SKIL SKIL SPRED1 SPRED1 FOXM1 FOXM1 SPIRE2 SPIRE2 VPS72 VPS72 EYA1 EYA1 KMT5B KMT5B DMAP1 DMAP1 FAM168A FAM168A CEBPG CEBPG brca1 brca1 SLF1 SLF1 PNKP PNKP RUVBL2 RUVBL2 PLA2R1 PLA2R1 UBE2V2 UBE2V2 PRKDC PRKDC SPIDR SPIDR ACTR8 ACTR8 HIC1 HIC1 ERCC6 ERCC6 PARP3 PARP3 zcwpw1 zcwpw1 POGZ POGZ BCL7A BCL7A ABRAXAS1 ABRAXAS1 SIRT6 SIRT6 FANCB FANCB SIRT1 SIRT1 EYA4 EYA4 mcrs1 mcrs1 MYC MYC G1KJZ5_ANOCA G1KJZ5_ANOCA INO80E INO80E FH FH DTX3L DTX3L PARP9 PARP9 BABAM2 BABAM2 WDR48 WDR48 smchd1 smchd1 ERCC8 ERCC8 G1KWK2_ANOCA G1KWK2_ANOCA H9GRZ9_ANOCA H9GRZ9_ANOCA DDX11 DDX11 PCNA PCNA BRCC3 BRCC3 LOC100567827 LOC100567827 H9G467_ANOCA H9G467_ANOCA ddx5 ddx5 HDGFL2 HDGFL2 RNF8 RNF8 MMS19 MMS19 ACTR2 ACTR2 rps3 rps3 MBTD1 MBTD1 ARID2 ARID2 LOC100554464 LOC100554464 FBH1 FBH1 LOC100556408 LOC100556408 eef1e1 eef1e1 WRAP53 WRAP53 EPC2 EPC2 NSMCE1 NSMCE1 INO80 INO80 slf2 slf2 FXR1 FXR1 INO80D INO80D xrcc1 xrcc1 LOC100565669 LOC100565669 MFSD11 MFSD11 MGMT MGMT YEATS4 YEATS4 ACTL6A ACTL6A ATR ATR DHX9 DHX9 atm atm UIMC1 UIMC1 MAP3K20 MAP3K20 PARP1 PARP1 BRD8 BRD8 EPC1 EPC1 UCHL5 UCHL5 FMR1 FMR1 ANKRD1 ANKRD1 RBBP8 RBBP8 BCL7C BCL7C ZNF385A ZNF385A RUVBL1 RUVBL1 R4GDA8_ANOCA R4GDA8_ANOCA R4GDH7_ANOCA R4GDH7_ANOCA LOC100559058 LOC100559058 ankle1 ankle1 R4G943_ANOCA R4G943_ANOCA KMT5C KMT5C HELQ HELQ LOC100559702 LOC100559702 LOC100567829 LOC100567829 G1KY24_ANOCA G1KY24_ANOCA RIF1 RIF1 G1KVX5_ANOCA G1KVX5_ANOCA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H9GVW7_ANOCAReverse transcriptase domain-containing protein. (356 aa)
R4G9N3_ANOCAReverse transcriptase domain-containing protein. (295 aa)
FAM178BFamily with sequence similarity 178 member B. (461 aa)
ENSACAP00000022017annotation not available (305 aa)
MRGBPMRG domain binding protein. (240 aa)
R4GAZ5_ANOCAReverse transcriptase domain-containing protein. (767 aa)
R4GCF9_ANOCAReverse transcriptase domain-containing protein. (771 aa)
R4GCI0_ANOCAReverse transcriptase domain-containing protein. (300 aa)
R4GCV3_ANOCAReverse transcriptase domain-containing protein. (933 aa)
G1KVT4_ANOCAReverse transcriptase domain-containing protein. (399 aa)
PIAS4Protein inhibitor of activated STAT 4. (212 aa)
LOC103282487FAM35_C domain-containing protein. (146 aa)
H9GQ09_ANOCAFAM35_C domain-containing protein. (867 aa)
NFRKBNuclear factor related to kappaB binding protein. (1335 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (570 aa)
BCLAF1BCL2 associated transcription factor 1. (918 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (533 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (577 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3856 aa)
PBKProtein kinase domain-containing protein. (329 aa)
mrnipUncharacterized protein. (120 aa)
TFPTTCF3 fusion partner. (245 aa)
SKILSKI like proto-oncogene. (690 aa)
SPRED1Sprouty related EVH1 domain containing 1. (448 aa)
FOXM1Forkhead box M1. (754 aa)
SPIRE2Spire type actin nucleation factor 2. (486 aa)
VPS72Vacuolar protein sorting 72 homolog. (329 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (570 aa)
KMT5BLysine methyltransferase 5B. (888 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (465 aa)
FAM168AFamily with sequence similarity 168 member A. (235 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
brca1Uncharacterized protein. (772 aa)
SLF1SMC5-SMC6 complex localization factor 1. (938 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (568 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
PLA2R1Phospholipase A2 receptor 1. (1473 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (147 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4100 aa)
SPIDRScaffold protein involved in DNA repair. (990 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (641 aa)
HIC1HIC ZBTB transcriptional repressor 1. (637 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1440 aa)
PARP3Poly [ADP-ribose] polymerase. (542 aa)
zcwpw1Uncharacterized protein. (211 aa)
POGZPogo transposable element derived with ZNF domain. (1447 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (180 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (404 aa)
SIRT6Sirtuin 6. (176 aa)
FANCBFA complementation group B. (836 aa)
SIRT1Sirtuin 1. (634 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (640 aa)
mcrs1FHA domain-containing protein. (449 aa)
MYCTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (443 aa)
G1KJZ5_ANOCAUncharacterized protein. (266 aa)
INO80EINO80 complex subunit E. (253 aa)
FHFumarate hydratase. (467 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (759 aa)
PARP9Poly [ADP-ribose] polymerase. (803 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
WDR48WD repeat domain 48. (692 aa)
smchd1SMC hinge domain-containing protein. (508 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (354 aa)
G1KWK2_ANOCAReverse transcriptase domain-containing protein. (294 aa)
H9GRZ9_ANOCAUncharacterized protein. (583 aa)
DDX11DEAD/H-box helicase 11. (914 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (261 aa)
LOC100567827Uncharacterized protein; Belongs to the actin family. (366 aa)
H9G467_ANOCAUncharacterized protein. (586 aa)
ddx5Uncharacterized protein; Belongs to the DEAD box helicase family. (600 aa)
HDGFL2HDGF like 2. (420 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (958 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (414 aa)
rps3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
MBTD1Mbt domain containing 1. (622 aa)
ARID2AT-rich interaction domain 2. (1840 aa)
LOC100554464FHA domain-containing protein. (118 aa)
FBH1F-box DNA helicase 1. (1043 aa)
LOC100556408FAT domain-containing protein. (2448 aa)
eef1e1GST C-terminal domain-containing protein. (180 aa)
WRAP53WD repeat containing antisense to TP53. (383 aa)
EPC2Enhancer of polycomb homolog. (806 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (232 aa)
INO80INO80 complex ATPase subunit. (1421 aa)
slf2Uncharacterized protein. (1187 aa)
FXR1FMR1 autosomal homolog 1. (665 aa)
INO80DINO80 complex subunit D. (1042 aa)
xrcc1Uncharacterized protein. (656 aa)
LOC100565669Uncharacterized protein. (1422 aa)
MFSD11Major facilitator superfamily domain containing 11. (396 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (118 aa)
YEATS4YEATS domain containing 4. (227 aa)
ACTL6AActin like 6A; Belongs to the actin family. (486 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2649 aa)
DHX9DExH-box helicase 9. (1261 aa)
atmUncharacterized protein; Belongs to the PI3/PI4-kinase family. (423 aa)
UIMC1Ubiquitin interaction motif containing 1. (714 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (937 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
BRD8Bromodomain containing 8. (1252 aa)
EPC1Enhancer of polycomb homolog. (742 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (331 aa)
FMR1Fragile X mental retardation 1. (618 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
RBBP8RB binding protein 8, endonuclease. (897 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (226 aa)
ZNF385AZinc finger protein 385A. (376 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
R4GDA8_ANOCAReverse transcriptase domain-containing protein. (1252 aa)
R4GDH7_ANOCAUncharacterized protein. (271 aa)
LOC100559058KIND domain-containing protein. (350 aa)
ankle1Uncharacterized protein. (470 aa)
R4G943_ANOCAReverse transcriptase domain-containing protein. (305 aa)
KMT5CLysine methyltransferase 5C. (472 aa)
HELQHelicase, POLQ like. (1045 aa)
LOC100559702Uncharacterized protein. (117 aa)
LOC100567829Uncharacterized protein. (201 aa)
G1KY24_ANOCAReverse transcriptase domain-containing protein. (317 aa)
RIF1Replication timing regulatory factor 1. (2361 aa)
G1KVX5_ANOCAProtein kinase domain-containing protein. (147 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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