(22 nodes) Regulation of double-strand break repair via nonhomologous end joining network (Anolis carolinensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100568010	Uncharacterized protein. (266 aa)
	POT1	Protection of telomeres 1. (774 aa)
	DEK	DEK proto-oncogene. (380 aa)
	WRAP53	WD repeat containing antisense to TP53. (383 aa)
	hmga2	Uncharacterized protein. (72 aa)
	NSD2	Nuclear receptor binding SET domain protein 2. (1217 aa)
	LOC100565669	Uncharacterized protein. (1422 aa)
	smchd1	SMC hinge domain-containing protein. (508 aa)
	PARP9	Poly [ADP-ribose] polymerase. (803 aa)
	DTX3L	Deltex E3 ubiquitin ligase 3L. (759 aa)
	FH	Fumarate hydratase. (467 aa)
	G1KJZ5_ANOCA	Uncharacterized protein. (266 aa)
	SIRT7	Sirtuin 7. (334 aa)
	PARP3	Poly [ADP-ribose] polymerase. (542 aa)
	ERCC6	ERCC excision repair 6, chromatin remodeling factor. (1440 aa)
	PRKDC	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4100 aa)
	PNKP	Polynucleotide kinase 3'-phosphatase. (568 aa)
	KMT5B	Lysine methyltransferase 5B. (888 aa)
	mrnip	Uncharacterized protein. (120 aa)
	LOC103282487	FAM35_C domain-containing protein. (146 aa)
	KMT5C	Lysine methyltransferase 5C. (472 aa)
	RIF1	Replication timing regulatory factor 1. (2361 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEK	ERCC6	ENSACAP00000003164	ENSACAP00000011492	DEK proto-oncogene.	ERCC excision repair 6, chromatin remodeling factor.	0.668
DTX3L	PARP9	ENSACAP00000009525	ENSACAP00000009516	Deltex E3 ubiquitin ligase 3L.	Poly [ADP-ribose] polymerase.	0.984
ERCC6	DEK	ENSACAP00000011492	ENSACAP00000003164	ERCC excision repair 6, chromatin remodeling factor.	DEK proto-oncogene.	0.668
KMT5C	NSD2	ENSACAP00000019798	ENSACAP00000007827	Lysine methyltransferase 5C.	Nuclear receptor binding SET domain protein 2.	0.509
LOC100565669	smchd1	ENSACAP00000008677	ENSACAP00000008864	Uncharacterized protein.	SMC hinge domain-containing protein.	0.948
NSD2	KMT5C	ENSACAP00000007827	ENSACAP00000019798	Nuclear receptor binding SET domain protein 2.	Lysine methyltransferase 5C.	0.509
NSD2	PRKDC	ENSACAP00000007827	ENSACAP00000011890	Nuclear receptor binding SET domain protein 2.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.601
NSD2	RIF1	ENSACAP00000007827	ENSACAP00000020609	Nuclear receptor binding SET domain protein 2.	Replication timing regulatory factor 1.	0.560
PARP3	PARP9	ENSACAP00000011424	ENSACAP00000009516	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.548
PARP3	PRKDC	ENSACAP00000011424	ENSACAP00000011890	Poly [ADP-ribose] polymerase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.436
PARP9	DTX3L	ENSACAP00000009516	ENSACAP00000009525	Poly [ADP-ribose] polymerase.	Deltex E3 ubiquitin ligase 3L.	0.984
PARP9	PARP3	ENSACAP00000009516	ENSACAP00000011424	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.548
PNKP	PRKDC	ENSACAP00000012550	ENSACAP00000011890	Polynucleotide kinase 3'-phosphatase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.586
POT1	WRAP53	ENSACAP00000001233	ENSACAP00000003181	Protection of telomeres 1.	WD repeat containing antisense to TP53.	0.653
PRKDC	NSD2	ENSACAP00000011890	ENSACAP00000007827	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Nuclear receptor binding SET domain protein 2.	0.601
PRKDC	PARP3	ENSACAP00000011890	ENSACAP00000011424	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Poly [ADP-ribose] polymerase.	0.436
PRKDC	PNKP	ENSACAP00000011890	ENSACAP00000012550	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Polynucleotide kinase 3'-phosphatase.	0.586
PRKDC	RIF1	ENSACAP00000011890	ENSACAP00000020609	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Replication timing regulatory factor 1.	0.589
RIF1	NSD2	ENSACAP00000020609	ENSACAP00000007827	Replication timing regulatory factor 1.	Nuclear receptor binding SET domain protein 2.	0.560
RIF1	PRKDC	ENSACAP00000020609	ENSACAP00000011890	Replication timing regulatory factor 1.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.589