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| | CENPK | Centromere protein K. (285 aa) |
| | bod1 | Uncharacterized protein. (193 aa) |
| | kif2c | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (719 aa) |
| | KMT5B | Lysine methyltransferase 5B. (888 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (382 aa) |
| | bub1b | BUB1 N-terminal domain-containing protein. (1062 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (570 aa) |
| | CBX5 | Chromobox 5. (188 aa) |
| | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1056 aa) |
| | G1KN42_ANOCA | CENP-C_C domain-containing protein. (239 aa) |
| | CBX3 | Chromobox 3. (184 aa) |
| | H9GHQ1_ANOCA | Uncharacterized protein. (755 aa) |
| | SKA2 | Spindle and kinetochore associated complex subunit 2. (130 aa) |
| | SIRT6 | Sirtuin 6. (176 aa) |
| | RECQL4 | RecQ like helicase 4. (1239 aa) |
| | WDSUB1 | WD repeat, sterile alpha motif and U-box domain containing 1. (495 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (761 aa) |
| | mis12 | Uncharacterized protein. (204 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1065 aa) |
| | ska1 | Uncharacterized protein. (253 aa) |
| | ZWILCH | Zwilch kinetochore protein. (600 aa) |
| | G1KJ64_ANOCA | Uncharacterized protein. (311 aa) |
| | H9GVX0_ANOCA | Uncharacterized protein. (179 aa) |
| | LOC100562004 | F-box domain-containing protein. (173 aa) |
| | spc24 | Uncharacterized protein. (199 aa) |
| | LOC100553961 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa) |
| | LOC100561388 | Uncharacterized protein. (206 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (344 aa) |
| | CKAP5 | Cytoskeleton associated protein 5. (2057 aa) |
| | hjurp | Uncharacterized protein. (836 aa) |
| | cenpq | Centromere protein Q. (249 aa) |
| | HELLS | Helicase, lymphoid specific. (750 aa) |
| | itgb3bp | Integrin subunit beta 3 binding protein. (196 aa) |
| | BOD1L1 | Biorientation of chromosomes in cell division 1 like 1. (3013 aa) |
| | DCLRE1B | DNA cross-link repair 1B. (309 aa) |
| | DMRT2 | Doublesex and mab-3 related transcription factor 2. (542 aa) |
| | Ska3 | Uncharacterized protein. (52 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1286 aa) |
| | WRN | WRN RecQ like helicase. (1315 aa) |
| | TERF2 | Telomeric repeat binding factor 2. (696 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (232 aa) |
| | Tinf2 | TINF2_N domain-containing protein. (223 aa) |
| | dsn1 | Uncharacterized protein. (281 aa) |
| | NUF2 | NUF2 component of NDC80 kinetochore complex. (459 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (361 aa) |
| | ZW10 | Zw10 kinetochore protein. (809 aa) |
| | CENPN | Centromere protein N. (372 aa) |
| | NDC80 | NDC80 kinetochore complex component. (645 aa) |
| | atrx | Uncharacterized protein. (2338 aa) |
| | rcc2 | Uncharacterized protein. (444 aa) |
| | GPATCH11 | G-patch domain containing 11. (188 aa) |
| | IKZF1 | IKAROS family zinc finger 1. (585 aa) |
| | CENPI | Centromere protein I. (738 aa) |
| | FBXO28 | Uncharacterized protein. (131 aa) |
| | LOC100558393 | Uncharacterized protein. (289 aa) |
| | ten1 | Uncharacterized protein. (125 aa) |
| | H9GCY1_ANOCA | Rap1_C domain-containing protein. (116 aa) |
| | G1KGW4_ANOCA | FHA domain-containing protein. (1533 aa) |
| | H9GBT6_ANOCA | TOG domain-containing protein. (754 aa) |
| | CBX1 | Chromobox 1. (189 aa) |
| | LOC100554279 | Uncharacterized protein. (211 aa) |
| | NSL1 | NSL1 component of MIS12 kinetochore complex. (268 aa) |
| | ZBTB48 | Zinc finger and BTB domain containing 48. (281 aa) |
| | CENPF | Centromere protein F. (2167 aa) |
| | CENPL | Centromere protein L. (353 aa) |
| | SGO1 | Shugoshin 1. (534 aa) |
| | CENPO | Centromere protein O. (320 aa) |
| | SMC5 | Structural maintenance of chromosomes 5. (1079 aa) |
| | NCAPD3 | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1494 aa) |
| | ZNF618 | Zinc finger protein 618. (884 aa) |
| | SPC25 | SPC25 component of NDC80 kinetochore complex. (215 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (111 aa) |
| | POT1 | Protection of telomeres 1. (774 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) |
| | Cenpt | CENP-T_C domain-containing protein. (70 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1334 aa) |
| | CHAMP1 | Chromosome alignment maintaining phosphoprotein 1. (812 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa) |
| | KNTC1 | Kinetochore associated 1. (2143 aa) |
| | NDE1 | NudE neurodevelopment protein 1. (174 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2361 aa) |
| | LOC103283027 | Uncharacterized protein. (264 aa) |
| | TERB1 | Telomere repeat binding bouquet formation protein 1. (774 aa) |
| | ZNF827 | Zinc finger protein 827. (763 aa) |
| | KMT5C | Lysine methyltransferase 5C. (472 aa) |
| | MTBP | MDM2 binding protein. (922 aa) |
| | DHX36 | DEAH-box helicase 36. (981 aa) |
| | H9GSH6_ANOCA | Uncharacterized protein. (248 aa) |
| | LOC103282595 | Uncharacterized protein. (126 aa) |
| | G1KVB7_ANOCA | Uncharacterized protein. (163 aa) |
| | H9GQL3_ANOCA | Uncharacterized protein. (672 aa) |
| | RPA2 | Replication protein A2. (268 aa) |
| | TTK | TTK protein kinase. (883 aa) |
| | SAPCD1 | Suppressor APC domain containing 1. (119 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (346 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (172 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (139 aa) |
| | CENPH | Centromere protein H. (237 aa) |
| | NEK2 | NIMA related kinase 2. (446 aa) |
| | SPDL1 | Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (629 aa) |
