(78 nodes) Tyrosine-specific protein phosphatases domain network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPN21	Protein tyrosine phosphatase non-receptor type 21. (1190 aa)
	PTPRT	Protein tyrosine phosphatase receptor type T. (1442 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1781 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1218 aa)
	dusp14	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (199 aa)
	PTPRQ	Protein tyrosine phosphatase receptor type Q. (2301 aa)
	RNGTT	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (575 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (404 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (366 aa)
	CDKN3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
	LOC100552176	Uncharacterized protein. (512 aa)
	DUSP22	Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (206 aa)
	PTPN4	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (930 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (658 aa)
	cdc14b	Uncharacterized protein. (477 aa)
	H9GRD3_ANOCA	Uncharacterized protein. (444 aa)
	G1KWH5_ANOCA	Uncharacterized protein. (155 aa)
	MTMR1	Myotubularin related protein 1. (586 aa)
	DUSP8	Dual specificity phosphatase 8. (647 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (425 aa)
	PTPRN2	Protein tyrosine phosphatase receptor type N2. (1016 aa)
	LOC100564881	Uncharacterized protein. (549 aa)
	PTPN20	Protein tyrosine phosphatase non-receptor type 20. (316 aa)
	SSH1	Slingshot protein phosphatase 1. (830 aa)
	PTPRK	Protein tyrosine phosphatase receptor type K. (1479 aa)
	LOC100567223	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (191 aa)
	DUSP21	Dual specificity phosphatase 21; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
	DUSP27	Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1084 aa)
	TNS2	Tensin 2. (1329 aa)
	PTP4A1	Protein tyrosine phosphatase 4A1. (173 aa)
	DUSP9	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (358 aa)
	dupd1	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. (217 aa)
	DUSP13	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (209 aa)
	DUSP12	Dual specificity phosphatase 12. (311 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1902 aa)
	SSH3	Slingshot protein phosphatase 3. (615 aa)
	Ptpre	Uncharacterized protein. (383 aa)
	EPM2A	EPM2A glucan phosphatase, laforin. (220 aa)
	PTPN6	Protein tyrosine phosphatase non-receptor type 6. (369 aa)
	PTPN3	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (929 aa)
	PTPRZ1	Protein tyrosine phosphatase receptor type Z1. (2281 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (400 aa)
	STYX	Serine/threonine/tyrosine interacting protein. (219 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1269 aa)
	MTMR7	Myotubularin related protein 7. (657 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1186 aa)
	ptpn18	Uncharacterized protein. (546 aa)
	DUSP5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (407 aa)
	LOC100551628	Uncharacterized protein. (213 aa)
	PTPRD	Protein tyrosine phosphatase receptor type D. (1964 aa)
	dusp3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	DUSP16	Dual specificity phosphatase 16. (661 aa)
	LOC100555140	Protein-tyrosine-phosphatase. (1719 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (364 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (361 aa)
	ptprm	Protein tyrosine phosphatase receptor type M. (561 aa)
	CDC14A	Cell division cycle 14A. (611 aa)
	PTPN11	Protein tyrosine phosphatase non-receptor type 11. (513 aa)
	PTPRG	Protein tyrosine phosphatase receptor type G. (1213 aa)
	DUSP10	Dual specificity phosphatase 10. (482 aa)
	PTPMT1	Protein tyrosine phosphatase mitochondrial 1. (218 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2230 aa)
	DUSP11	Dual specificity phosphatase 11. (205 aa)
	styxl1	Tyrosine-protein phosphatase domain-containing protein. (332 aa)
	PTPRU	Protein tyrosine phosphatase receptor type U. (1368 aa)
	ptpn23	Uncharacterized protein. (1434 aa)
	DUSP26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
	PTP4A3	Protein tyrosine phosphatase 4A3. (173 aa)
	MTMR4	Myotubularin related protein 4. (555 aa)
	PTPDC1	Protein tyrosine phosphatase domain containing 1. (732 aa)
	DUSP23	Dual specificity phosphatase 23. (151 aa)
	PTPN22	Protein tyrosine phosphatase non-receptor type 22. (745 aa)
	ptprj	Uncharacterized protein. (1332 aa)
	PTPN5	Protein tyrosine phosphatase non-receptor type 5. (526 aa)
	MTMR2	Myotubularin related protein 2. (614 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2466 aa)
	SSH2	Slingshot protein phosphatase 2. (1361 aa)
	PTPRN	Protein tyrosine phosphatase receptor type N. (932 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC14A	cdc14b	ENSACAP00000003139	ENSACAP00000018406	Cell division cycle 14A.	Uncharacterized protein.	0.940
DUSP6	DUSP9	ENSACAP00000011637	ENSACAP00000008975	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.453
DUSP7	DUSP9	ENSACAP00000006727	ENSACAP00000008975	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.442
DUSP9	DUSP6	ENSACAP00000008975	ENSACAP00000011637	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.453
DUSP9	DUSP7	ENSACAP00000008975	ENSACAP00000006727	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.442
EPM2A	dusp3	ENSACAP00000007266	ENSACAP00000004668	EPM2A glucan phosphatase, laforin.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.405
G1KWH5_ANOCA	LOC100564881	ENSACAP00000019331	ENSACAP00000011347	Uncharacterized protein.	Uncharacterized protein.	0.454
G1KWH5_ANOCA	Ptpre	ENSACAP00000019331	ENSACAP00000007491	Uncharacterized protein.	Uncharacterized protein.	0.899
LOC100564881	G1KWH5_ANOCA	ENSACAP00000011347	ENSACAP00000019331	Uncharacterized protein.	Uncharacterized protein.	0.454
LOC100564881	PTPN6	ENSACAP00000011347	ENSACAP00000006989	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 6.	0.444
MTMR2	MTMR4	ENSACAP00000013382	ENSACAP00000000603	Myotubularin related protein 2.	Myotubularin related protein 4.	0.904
MTMR2	MTMR7	ENSACAP00000013382	ENSACAP00000006281	Myotubularin related protein 2.	Myotubularin related protein 7.	0.936
MTMR4	MTMR2	ENSACAP00000000603	ENSACAP00000013382	Myotubularin related protein 4.	Myotubularin related protein 2.	0.904
MTMR4	MTMR7	ENSACAP00000000603	ENSACAP00000006281	Myotubularin related protein 4.	Myotubularin related protein 7.	0.942
MTMR4	RNGTT	ENSACAP00000000603	ENSACAP00000014532	Myotubularin related protein 4.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.515
MTMR7	MTMR2	ENSACAP00000006281	ENSACAP00000013382	Myotubularin related protein 7.	Myotubularin related protein 2.	0.936
MTMR7	MTMR4	ENSACAP00000006281	ENSACAP00000000603	Myotubularin related protein 7.	Myotubularin related protein 4.	0.942
PTPN11	PTPN6	ENSACAP00000002937	ENSACAP00000006989	Protein tyrosine phosphatase non-receptor type 11.	Protein tyrosine phosphatase non-receptor type 6.	0.433
PTPN5	PTPN7	ENSACAP00000000066	ENSACAP00000004268	Protein tyrosine phosphatase non-receptor type 5.	Protein tyrosine phosphatase non-receptor type 7.	0.933
PTPN5	PTPRR	ENSACAP00000000066	ENSACAP00000017883	Protein tyrosine phosphatase non-receptor type 5.	Protein tyrosine phosphatase receptor type R.	0.930