30 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	exosc7	RNase_PH domain-containing protein. (168 aa)
	hsp90aa1	HATPase_c domain-containing protein. (728 aa)
	MRPS5	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (407 aa)
	IMPACT	Impact RWD domain protein. (318 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1559 aa)
	FCSK	Fucose kinase. (1099 aa)
	RPS2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (298 aa)
	EXOSC5	Exosome component 5. (223 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (792 aa)
	EXOSC4	Exosome component 4. (191 aa)
	GFM2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (778 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1638 aa)
	MLH1	MutL homolog 1. (746 aa)
	EFL1	Elongation factor like GTPase 1. (1127 aa)
	MRPS9	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (368 aa)
	EEF2	Eukaryotic translation elongation factor 2. (859 aa)
	EXOSC9	Exosome component 9. (439 aa)
	TRAP1	TNF receptor associated protein 1. (674 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (846 aa)
	RPS16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	LONP2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (852 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (727 aa)
	GALK2	Galactokinase 2. (458 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (795 aa)
	MLH3	MutL homolog 3. (1385 aa)
	PMS1	PMS1 homolog 1, mismatch repair system component. (943 aa)
	MVD	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (405 aa)
	GFM1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (739 aa)
	GALK1	Galactokinase 1. (394 aa)
	EFTUD2	Elongation factor Tu GTP binding domain containing 2. (972 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF2	HSP90AB1	ENSACAP00000012138	ENSACAP00000014598	Eukaryotic translation elongation factor 2.	Heat shock protein 90 alpha family class B member 1.	0.556
EEF2	HSP90B1	ENSACAP00000012138	ENSACAP00000015990	Eukaryotic translation elongation factor 2.	Heat shock protein 90 beta family member 1.	0.492
EEF2	MRPS5	ENSACAP00000012138	ENSACAP00000000806	Eukaryotic translation elongation factor 2.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.827
EEF2	MRPS9	ENSACAP00000012138	ENSACAP00000011105	Eukaryotic translation elongation factor 2.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.932
EEF2	PNPT1	ENSACAP00000012138	ENSACAP00000003735	Eukaryotic translation elongation factor 2.	Polyribonucleotide nucleotidyltransferase 1.	0.616
EEF2	RPS16	ENSACAP00000012138	ENSACAP00000013921	Eukaryotic translation elongation factor 2.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.999
EEF2	RPS2	ENSACAP00000012138	ENSACAP00000002477	Eukaryotic translation elongation factor 2.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.999
EEF2	TOP2A	ENSACAP00000012138	ENSACAP00000002284	Eukaryotic translation elongation factor 2.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.547
EEF2	TOP2B	ENSACAP00000012138	ENSACAP00000009044	Eukaryotic translation elongation factor 2.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.724
EEF2	TRAP1	ENSACAP00000012138	ENSACAP00000012640	Eukaryotic translation elongation factor 2.	TNF receptor associated protein 1.	0.499
EEF2	hsp90aa1	ENSACAP00000012138	ENSACAP00000000156	Eukaryotic translation elongation factor 2.	HATPase_c domain-containing protein.	0.556
EFL1	MRPS5	ENSACAP00000010836	ENSACAP00000000806	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.827
EFL1	MRPS9	ENSACAP00000010836	ENSACAP00000011105	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.932
EFL1	PNPT1	ENSACAP00000010836	ENSACAP00000003735	Elongation factor like GTPase 1.	Polyribonucleotide nucleotidyltransferase 1.	0.616
EFL1	RPS16	ENSACAP00000010836	ENSACAP00000013921	Elongation factor like GTPase 1.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.783
EFL1	RPS2	ENSACAP00000010836	ENSACAP00000002477	Elongation factor like GTPase 1.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.827
EFL1	TOP2A	ENSACAP00000010836	ENSACAP00000002284	Elongation factor like GTPase 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.519
EFL1	TOP2B	ENSACAP00000010836	ENSACAP00000009044	Elongation factor like GTPase 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.519
EFTUD2	MRPS5	ENSACAP00000007670	ENSACAP00000000806	Elongation factor Tu GTP binding domain containing 2.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.827
EFTUD2	MRPS9	ENSACAP00000007670	ENSACAP00000011105	Elongation factor Tu GTP binding domain containing 2.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.932