(13 nodes) GroEL-like apical domain superfamily network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TCP1	T-complex 1. (548 aa)
	CCT8L2	Chaperonin containing TCP1 subunit 8 like 2. (549 aa)
	CCT8	Chaperonin containing TCP1 subunit 8. (548 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	CCT7	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (498 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2125 aa)
	BBS10	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family. (695 aa)
	CCT5	Chaperonin containing TCP1 subunit 5. (541 aa)
	CCT3	T-complex protein 1 subunit gamma. (545 aa)
	BBS12	Bardet-Biedl syndrome 12. (608 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (677 aa)
	CCT4	T-complex protein 1 subunit delta. (544 aa)
	CCT2	Chaperonin containing TCP1 subunit 2. (534 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS10	BBS12	ENSACAP00000009907	ENSACAP00000020510	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Bardet-Biedl syndrome 12.	0.946
BBS10	CCT2	ENSACAP00000009907	ENSACAP00000004473	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Chaperonin containing TCP1 subunit 2.	0.977
BBS10	CCT3	ENSACAP00000009907	ENSACAP00000013023	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	T-complex protein 1 subunit gamma.	0.954
BBS10	CCT4	ENSACAP00000009907	ENSACAP00000005561	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	T-complex protein 1 subunit delta.	0.920
BBS10	CCT5	ENSACAP00000009907	ENSACAP00000010334	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Chaperonin containing TCP1 subunit 5.	0.974
BBS10	CCT7	ENSACAP00000009907	ENSACAP00000000560	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.973
BBS10	CCT8	ENSACAP00000009907	ENSACAP00000001856	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Chaperonin containing TCP1 subunit 8.	0.915
BBS10	CCT8L2	ENSACAP00000009907	ENSACAP00000009738	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Chaperonin containing TCP1 subunit 8 like 2.	0.972
BBS10	HSPD1	ENSACAP00000009907	ENSACAP00000009377	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family.	0.557
BBS10	MKKS	ENSACAP00000009907	ENSACAP00000001803	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	McKusick-Kaufman syndrome.	0.651
BBS10	TCP1	ENSACAP00000009907	ENSACAP00000004250	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	T-complex 1.	0.547
BBS12	BBS10	ENSACAP00000020510	ENSACAP00000009907	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 10; Belongs to the TCP-1 chaperonin family.	0.946
BBS12	CCT2	ENSACAP00000020510	ENSACAP00000004473	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1 subunit 2.	0.487
BBS12	CCT3	ENSACAP00000020510	ENSACAP00000013023	Bardet-Biedl syndrome 12.	T-complex protein 1 subunit gamma.	0.487
BBS12	CCT4	ENSACAP00000020510	ENSACAP00000005561	Bardet-Biedl syndrome 12.	T-complex protein 1 subunit delta.	0.487
BBS12	CCT5	ENSACAP00000020510	ENSACAP00000010334	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1 subunit 5.	0.487
BBS12	CCT8	ENSACAP00000020510	ENSACAP00000001856	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1 subunit 8.	0.575
BBS12	CCT8L2	ENSACAP00000020510	ENSACAP00000009738	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1 subunit 8 like 2.	0.475
BBS12	MKKS	ENSACAP00000020510	ENSACAP00000001803	Bardet-Biedl syndrome 12.	McKusick-Kaufman syndrome.	0.758
BBS12	TCP1	ENSACAP00000020510	ENSACAP00000004250	Bardet-Biedl syndrome 12.	T-complex 1.	0.625