21 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDK2	Protein-serine/threonine kinase. (408 aa)
	BCKDK	Protein-serine/threonine kinase. (414 aa)
	PDK3	Protein-serine/threonine kinase. (413 aa)
	morc2	CW-type domain-containing protein. (1031 aa)
	MLH1	MutL homolog 1. (746 aa)
	morc3	CW-type domain-containing protein. (932 aa)
	TRAP1	TNF receptor associated protein 1. (674 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (846 aa)
	PDK4	Protein-serine/threonine kinase. (492 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (727 aa)
	PDK1	Protein-serine/threonine kinase. (410 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (795 aa)
	MLH3	MutL homolog 3. (1385 aa)
	G1KXW1_ANOCA	Morc6_S5 domain-containing protein. (479 aa)
	MORC1	MORC family CW-type zinc finger 1. (964 aa)
	LOC100565669	Uncharacterized protein. (1422 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1638 aa)
	hsp90aa1	HATPase_c domain-containing protein. (728 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1559 aa)
	SACS	Sacsin molecular chaperone. (4592 aa)
	PMS1	PMS1 homolog 1, mismatch repair system component. (943 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSP90AB1	HSP90B1	ENSACAP00000014598	ENSACAP00000015990	Heat shock protein 90 alpha family class B member 1.	Heat shock protein 90 beta family member 1.	0.924
HSP90AB1	hsp90aa1	ENSACAP00000014598	ENSACAP00000000156	Heat shock protein 90 alpha family class B member 1.	HATPase_c domain-containing protein.	0.900
HSP90B1	HSP90AB1	ENSACAP00000015990	ENSACAP00000014598	Heat shock protein 90 beta family member 1.	Heat shock protein 90 alpha family class B member 1.	0.924
HSP90B1	hsp90aa1	ENSACAP00000015990	ENSACAP00000000156	Heat shock protein 90 beta family member 1.	HATPase_c domain-containing protein.	0.925
MLH1	MLH3	ENSACAP00000009935	ENSACAP00000016565	MutL homolog 1.	MutL homolog 3.	0.998
MLH1	PMS1	ENSACAP00000009935	ENSACAP00000004073	MutL homolog 1.	PMS1 homolog 1, mismatch repair system component.	0.993
MLH1	PMS2	ENSACAP00000009935	ENSACAP00000013064	MutL homolog 1.	PMS1 homolog 2, mismatch repair system component.	0.999
MLH1	TOP2A	ENSACAP00000009935	ENSACAP00000002284	MutL homolog 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.403
MLH1	TOP2B	ENSACAP00000009935	ENSACAP00000009044	MutL homolog 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.403
MLH3	MLH1	ENSACAP00000016565	ENSACAP00000009935	MutL homolog 3.	MutL homolog 1.	0.998
MLH3	PMS1	ENSACAP00000016565	ENSACAP00000004073	MutL homolog 3.	PMS1 homolog 1, mismatch repair system component.	0.856
MLH3	PMS2	ENSACAP00000016565	ENSACAP00000013064	MutL homolog 3.	PMS1 homolog 2, mismatch repair system component.	0.863
MORC1	morc2	ENSACAP00000007826	ENSACAP00000009822	MORC family CW-type zinc finger 1.	CW-type domain-containing protein.	0.419
PMS1	MLH1	ENSACAP00000004073	ENSACAP00000009935	PMS1 homolog 1, mismatch repair system component.	MutL homolog 1.	0.993
PMS1	MLH3	ENSACAP00000004073	ENSACAP00000016565	PMS1 homolog 1, mismatch repair system component.	MutL homolog 3.	0.856
PMS1	PMS2	ENSACAP00000004073	ENSACAP00000013064	PMS1 homolog 1, mismatch repair system component.	PMS1 homolog 2, mismatch repair system component.	0.883
PMS2	MLH1	ENSACAP00000013064	ENSACAP00000009935	PMS1 homolog 2, mismatch repair system component.	MutL homolog 1.	0.999
PMS2	MLH3	ENSACAP00000013064	ENSACAP00000016565	PMS1 homolog 2, mismatch repair system component.	MutL homolog 3.	0.863
PMS2	PMS1	ENSACAP00000013064	ENSACAP00000004073	PMS1 homolog 2, mismatch repair system component.	PMS1 homolog 1, mismatch repair system component.	0.883
TOP2A	MLH1	ENSACAP00000002284	ENSACAP00000009935	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	MutL homolog 1.	0.403