72 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	H9G6Z0_ANOCA	PDE4_UCR domain-containing protein. (155 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	PDE1A	Phosphodiesterase. (630 aa)
	LRBA	LPS responsive beige-like anchor protein. (2829 aa)
	THAP1	THAP domain containing 1. (220 aa)
	LOC100562262	WD_REPEATS_REGION domain-containing protein. (203 aa)
	nbea	Uncharacterized protein. (792 aa)
	Nbea	Uncharacterized protein. (837 aa)
	G1KCP9_ANOCA	Protein kinase domain-containing protein. (368 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	Cnbd2	Cyclic nucleotide-binding domain-containing protein. (285 aa)
	GNB1	G protein subunit beta 1. (333 aa)
	OPRM1	Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	LOC100553750	PDEase_I_N domain-containing protein. (123 aa)
	LOC103282364	Uncharacterized protein. (108 aa)
	ADCY3	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (734 aa)
	GNA11	G protein subunit alpha 11. (200 aa)
	GNA14	G protein subunit alpha 14. (390 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	SNX19	Sorting nexin 19. (999 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (432 aa)
	pde1b	Phosphodiesterase. (631 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1213 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (380 aa)
	G1KNF9_ANOCA	Phosphodiesterase. (502 aa)
	GNG10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC103279522	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (223 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (314 aa)
	THAP7	THAP domain containing 7. (301 aa)
	PDYN	Prodynorphin. (275 aa)
	POMC	Proopiomelanocortin. (240 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	PDE4B	Phosphodiesterase. (664 aa)
	adcy5	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (794 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	G1KKH9_ANOCA	AC_N domain-containing protein. (356 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1227 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (614 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
	Prkaca	Uncharacterized protein. (172 aa)
	PDE1C	Phosphodiesterase. (718 aa)
	LOC100564355	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (307 aa)
	gnai2	Uncharacterized protein. (333 aa)
	PDE4D	Phosphodiesterase. (701 aa)
	G1KIF1_ANOCA	Uncharacterized protein. (140 aa)
	PDE4A	Phosphodiesterase. (664 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (415 aa)
	GNAO1	G protein subunit alpha o1. (254 aa)
	CAMKK1	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily. (259 aa)
	gnaq	Uncharacterized protein. (359 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	prkx	Uncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	LOC103281581	Uncharacterized protein. (118 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	PLA2G4A	Phospholipase A2. (743 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1202 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1147 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSACAP00000007882	ENSACAP00000009989	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY1	ADCY3	ENSACAP00000007882	ENSACAP00000019460	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.578
ADCY1	ADCY4	ENSACAP00000007882	ENSACAP00000009399	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY1	ADCY6	ENSACAP00000007882	ENSACAP00000008442	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.442
ADCY1	ADCY7	ENSACAP00000007882	ENSACAP00000013999	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.469
ADCY1	ADCY8	ENSACAP00000007882	ENSACAP00000010472	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.955
ADCY1	ADCY9	ENSACAP00000007882	ENSACAP00000016127	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.668
ADCY1	G1KKH9_ANOCA	ENSACAP00000007882	ENSACAP00000010568	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AC_N domain-containing protein.	0.416
ADCY1	GNAI1	ENSACAP00000007882	ENSACAP00000015866	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.792
ADCY1	GNAI3	ENSACAP00000007882	ENSACAP00000010978	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.792
ADCY1	GNAO1	ENSACAP00000007882	ENSACAP00000007078	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha o1.	0.430
ADCY1	GNB1	ENSACAP00000007882	ENSACAP00000005114	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 1.	0.419
ADCY1	GNB3	ENSACAP00000007882	ENSACAP00000005693	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.785
ADCY1	GNB4	ENSACAP00000007882	ENSACAP00000004567	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 4.	0.788
ADCY1	GNB5	ENSACAP00000007882	ENSACAP00000010742	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.851
ADCY1	GNG10	ENSACAP00000007882	ENSACAP00000012393	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.845
ADCY1	GNG11	ENSACAP00000007882	ENSACAP00000013032	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.860
ADCY1	GNG2	ENSACAP00000007882	ENSACAP00000017613	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.812
ADCY1	GNG4	ENSACAP00000007882	ENSACAP00000001582	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.812
ADCY1	GNG5	ENSACAP00000007882	ENSACAP00000005611	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.845