STRINGSTRING
RTF1 RTF1 polr2j polr2j SUPT5H SUPT5H CCNH CCNH NELFCD NELFCD POLR2G POLR2G POLR2B POLR2B CCNT2 CCNT2 POLR2H POLR2H EAF1 EAF1 SUPT16H SUPT16H NCBP1 NCBP1 EAF2 EAF2 POLR2D POLR2D CDK9 CDK9 ELOB ELOB polr2c polr2c SSRP1 SSRP1 NELFA NELFA CCNT1 CCNT1 GTF2H4 GTF2H4 NELFE NELFE AFF1 AFF1 NELFB NELFB CCNK CCNK POLR2A POLR2A LOC100565538 LOC100565538 POLR2F POLR2F POLR2L POLR2L GTF2F1 GTF2F1 MLLT3 MLLT3 POLR2K POLR2K AFF4 AFF4 CTDP1 CTDP1 H9GUD4_ANOCA H9GUD4_ANOCA G1KZ53_ANOCA G1KZ53_ANOCA GTF2F2 GTF2F2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (668 aa)
polr2jRNA polymerase II subunit J. (117 aa)
SUPT5HTranscription elongation factor SPT5. (1081 aa)
CCNHCyclin H; Belongs to the cyclin family. (318 aa)
NELFCDNegative elongation factor complex member C/D. (582 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
CCNT2Cyclin T2. (586 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
EAF1ELL associated factor 1. (258 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1050 aa)
NCBP1Nuclear cap binding protein subunit 1. (918 aa)
EAF2ELL associated factor 2. (263 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
CDK9Cyclin dependent kinase 9. (197 aa)
ELOBElongin B. (119 aa)
polr2cRPOLD domain-containing protein. (275 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (705 aa)
NELFANegative elongation factor complex member A. (531 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (722 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
NELFENegative elongation factor complex member E. (359 aa)
AFF1AF4/FMR2 family member 1. (1210 aa)
NELFBNegative elongation factor complex member B. (577 aa)
CCNKCyclin K; Belongs to the cyclin family. (616 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
LOC100565538Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
MLLT3MLLT3 super elongation complex subunit. (577 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
AFF4AF4/FMR2 family member 4. (1173 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (958 aa)
H9GUD4_ANOCARPOLD domain-containing protein. (210 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
GTF2F2General transcription factor IIF subunit 2. (231 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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