STRINGSTRING
LOC100565538 LOC100565538 POLR2K POLR2K CDK7 CDK7 GTF2F1 GTF2F1 POLR2L POLR2L POLR2F POLR2F GTF2H3 GTF2H3 POLR2A POLR2A NELFB NELFB polr2j polr2j GTF2H1 GTF2H1 SUPT5H SUPT5H CCNH CCNH NELFCD NELFCD POLR2G POLR2G POLR2B POLR2B POLR2H POLR2H GTF2H4 GTF2H4 NELFE NELFE LOC100558064 LOC100558064 ERCC3 ERCC3 NELFA NELFA polr2c polr2c MNAT1 MNAT1 POLR2D POLR2D GTF2H5 GTF2H5 NCBP1 NCBP1 GTF2F2 GTF2F2 H9GVV6_ANOCA H9GVV6_ANOCA G1KZ53_ANOCA G1KZ53_ANOCA H9GUD4_ANOCA H9GUD4_ANOCA CTDP1 CTDP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100565538Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (345 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
GTF2H3General transcription factor IIH subunit 3. (311 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
NELFBNegative elongation factor complex member B. (577 aa)
polr2jRNA polymerase II subunit J. (117 aa)
GTF2H1General transcription factor IIH subunit 1. (571 aa)
SUPT5HTranscription elongation factor SPT5. (1081 aa)
CCNHCyclin H; Belongs to the cyclin family. (318 aa)
NELFCDNegative elongation factor complex member C/D. (582 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
NELFENegative elongation factor complex member E. (359 aa)
LOC100558064General transcription factor IIH subunit. (392 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (719 aa)
NELFANegative elongation factor complex member A. (531 aa)
polr2cRPOLD domain-containing protein. (275 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
NCBP1Nuclear cap binding protein subunit 1. (918 aa)
GTF2F2General transcription factor IIF subunit 2. (231 aa)
H9GVV6_ANOCAUncharacterized protein. (31 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
H9GUD4_ANOCARPOLD domain-containing protein. (210 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (958 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.