88 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAB2	Protein kinase AMP-activated non-catalytic subunit beta 2. (274 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)
	TKTL2	Transketolase like 2. (667 aa)
	LOC100551795	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (245 aa)
	R4G930_ANOCA	PKS_KS domain-containing protein. (233 aa)
	fap	Uncharacterized protein; Belongs to the peptidase S9B family. (763 aa)
	H9GUK2_ANOCA	Uncharacterized protein. (133 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	H9GU47_ANOCA	Uncharacterized protein. (73 aa)
	LOC100556364	BHLH domain-containing protein. (794 aa)
	H9GT90_ANOCA	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	H9GSB3_ANOCA	Biotin carboxylation domain-containing protein. (193 aa)
	GNA11	G protein subunit alpha 11. (200 aa)
	GNA14	G protein subunit alpha 14. (390 aa)
	LOC100555417	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (205 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	SNX19	Sorting nexin 19. (999 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2659 aa)
	SLC2A2	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (499 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	G1KRS0_ANOCA	BTB domain-containing protein. (183 aa)
	ADRA2A	Adrenoceptor alpha 2A. (451 aa)
	TALDO1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (921 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (432 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1213 aa)
	GCG	Glucagon. (86 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (820 aa)
	MLX	MAX dimerization protein MLX. (246 aa)
	LOC100552434	Uncharacterized protein. (78 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2073 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (380 aa)
	CACNA2D1	Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1113 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	GNG10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	AGPAT1	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (272 aa)
	LOC103279522	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (223 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa)
	MARCKS	Myristoylated alanine rich protein kinase C substrate. (284 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (314 aa)
	THAP7	THAP domain containing 7. (301 aa)
	G1KLC7_ANOCA	Ca_chan_IQ domain-containing protein. (872 aa)
	Cacna1d	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1136 aa)
	mlxip	BHLH domain-containing protein. (779 aa)
	adcy5	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (794 aa)
	TKT	Transketolase. (627 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	G1KKH9_ANOCA	AC_N domain-containing protein. (356 aa)
	LOC100553366	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (279 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2695 aa)
	FFAR1	Free fatty acid receptor 1. (293 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1843 aa)
	FASN	Fatty acid synthase. (2510 aa)
	Prkaca	Uncharacterized protein. (172 aa)
	ACACB	Acetyl-CoA carboxylase beta. (2203 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	Mlxipl	BHLH domain-containing protein. (154 aa)
	CACNA2D2	Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (694 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (565 aa)
	LOC100555911	G_PROTEIN_RECEP_F1_2 domain-containing protein. (436 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (817 aa)
	gnaq	Uncharacterized protein. (359 aa)
	LOC100564437	Uncharacterized protein. (342 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	THAP1	THAP domain containing 1. (220 aa)
	GNB1	G protein subunit beta 1. (333 aa)
	Cnbd2	Cyclic nucleotide-binding domain-containing protein. (285 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (718 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	LOC100562262	WD_REPEATS_REGION domain-containing protein. (203 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1147 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor like 1. (491 aa)
	ADIPOR1	Adiponectin receptor 1. (375 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (252 aa)
	Acaca	Uncharacterized protein. (1273 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (490 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	KCNS3	Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (502 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	KCNG2	Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (521 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1604 aa)
	KCNJ11	Potassium voltage-gated channel subfamily J member 11. (393 aa)
	ADIPOR2	Adiponectin receptor 2. (384 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	KCNJ11	ENSACAP00000000047	ENSACAP00000000046	ATP binding cassette subfamily C member 8.	Potassium voltage-gated channel subfamily J member 11.	0.999
ABCC8	LOC103279522	ENSACAP00000000047	ENSACAP00000011991	ATP binding cassette subfamily C member 8.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.456
ABCC8	Prkaca	ENSACAP00000000047	ENSACAP00000009669	ATP binding cassette subfamily C member 8.	Uncharacterized protein.	0.456
ABCC8	RAPGEF3	ENSACAP00000000047	ENSACAP00000014792	ATP binding cassette subfamily C member 8.	Rap guanine nucleotide exchange factor 3.	0.700
ABCC8	RAPGEF4	ENSACAP00000000047	ENSACAP00000006135	ATP binding cassette subfamily C member 8.	Rap guanine nucleotide exchange factor 4.	0.855
ABCC8	SLC2A2	ENSACAP00000000047	ENSACAP00000015859	ATP binding cassette subfamily C member 8.	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.445
ABCC8	prkacb	ENSACAP00000000047	ENSACAP00000023193	ATP binding cassette subfamily C member 8.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.456
ACACB	Acaca	ENSACAP00000009205	ENSACAP00000002314	Acetyl-CoA carboxylase beta.	Uncharacterized protein.	0.901
ACACB	FASN	ENSACAP00000009205	ENSACAP00000009733	Acetyl-CoA carboxylase beta.	Fatty acid synthase.	0.943
ACACB	H9GUK2_ANOCA	ENSACAP00000009205	ENSACAP00000020758	Acetyl-CoA carboxylase beta.	Uncharacterized protein.	0.896
ACACB	PRKAA2	ENSACAP00000009205	ENSACAP00000006688	Acetyl-CoA carboxylase beta.	Non-specific serine/threonine protein kinase.	0.920
ACACB	PRKAB2	ENSACAP00000009205	ENSACAP00000012971	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit beta 2.	0.910
ACACB	R4G930_ANOCA	ENSACAP00000009205	ENSACAP00000021710	Acetyl-CoA carboxylase beta.	PKS_KS domain-containing protein.	0.460
ACACB	RAPGEFL1	ENSACAP00000009205	ENSACAP00000002559	Acetyl-CoA carboxylase beta.	Rap guanine nucleotide exchange factor like 1.	0.429
ACSL4	FASN	ENSACAP00000012627	ENSACAP00000009733	Acyl-CoA synthetase long chain family member 4.	Fatty acid synthase.	0.921
ADCY6	GNB4	ENSACAP00000008442	ENSACAP00000004567	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 4.	0.751
ADCY6	GNB5	ENSACAP00000008442	ENSACAP00000010742	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.802
ADCY6	GNG10	ENSACAP00000008442	ENSACAP00000012393	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.795
ADCY6	GNG11	ENSACAP00000008442	ENSACAP00000013032	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.786
ADCY6	GNG2	ENSACAP00000008442	ENSACAP00000017613	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.765