STRINGSTRING
TRAF3 TRAF3 atf7 atf7 MAPK1 MAPK1 MAP2K3 MAP2K3 CREB5 CREB5 MAPKAPK3 MAPKAPK3 TAB3 TAB3 FOSB FOSB TONSL TONSL TAB1 TAB1 MAPK7 MAPK7 MAPKAPK2 MAPKAPK2 VWC2 VWC2 USP14 USP14 LOC100563741 LOC100563741 LOC103282606 LOC103282606 FNBP4 FNBP4 FOSL2 FOSL2 NFKBIB NFKBIB CREB1 CREB1 MAP2K7 MAP2K7 RPS6KA5 RPS6KA5 NAIP NAIP LRRC45 LRRC45 RIPK2 RIPK2 PPP2R1A PPP2R1A LRRC14 LRRC14 LRRC74B LRRC74B NKIRAS1 NKIRAS1 map2k6 map2k6 LOC100563825 LOC100563825 MAP3K7 MAP3K7 H9GUF0_ANOCA H9GUF0_ANOCA MAPK15 MAPK15 LOC103279342 LOC103279342 UBA52 UBA52 LOC103280697 LOC103280697 UBE2V1 UBE2V1 TANK TANK H9GRS7_ANOCA H9GRS7_ANOCA LRRC74A LRRC74A CCDC71L CCDC71L JUND JUND H9GQH1_ANOCA H9GQH1_ANOCA ubc ubc RIPK1 RIPK1 LOC100552241 LOC100552241 MAP2K4 MAP2K4 ATF1 ATF1 MAPK14 MAPK14 FOS FOS NKIRAS2 NKIRAS2 MAPK9 MAPK9 TRAF5 TRAF5 LRRC31 LRRC31 LRRC34 LRRC34 LRRC71 LRRC71 RPS6KA4 RPS6KA4 nlrc5 nlrc5 RPS6KA2 RPS6KA2 VWC2L VWC2L vrk3 vrk3 MAPK3 MAPK3 IRAK2 IRAK2 APP APP LOC100556649 LOC100556649 IRF3 IRF3 TLR4 TLR4 H9GK63_ANOCA H9GK63_ANOCA IKBKE IKBKE Ly96 Ly96 cd14 cd14 IKBKB IKBKB LOC103278612 LOC103278612 birc2 birc2 IKBKG IKBKG ube2n ube2n IRAK1 IRAK1 usp18 usp18 CHUK CHUK SARM1 SARM1 MAPK10 MAPK10 DUSP6 DUSP6 RELCH RELCH MAPK8 MAPK8 LOC100564881 LOC100564881 ATF2 ATF2 nfkbia nfkbia MAPK11 MAPK11 UBE2D2 UBE2D2 NLRX1 NLRX1 PPP2CA PPP2CA NOD1 NOD1 PTPN11 PTPN11 PPP2CB PPP2CB rps27a rps27a TBK1 TBK1 PPP4R1 PPP4R1 Fadd Fadd PPP4R4 PPP4R4 UBE2D1 UBE2D1 ELK1 ELK1 dusp3 dusp3 TRAF6 TRAF6 BIRC7 BIRC7 N4BP1 N4BP1 NFKB2 NFKB2 MAP3K20 MAP3K20 DUSP7 DUSP7 TAB2 TAB2 JUN JUN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (621 aa)
atf7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (478 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (500 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (695 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (163 aa)
TONSLTonsoku like, DNA repair protein. (1236 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (535 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (801 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (398 aa)
VWC2Von Willebrand factor C domain containing 2. (333 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (495 aa)
LOC100563741RNase_Zc3h12a domain-containing protein. (872 aa)
LOC103282606Protein kinase domain-containing protein. (316 aa)
FNBP4Formin binding protein 4. (961 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (325 aa)
NFKBIBNFKB inhibitor beta. (295 aa)
CREB1cAMP responsive element binding protein 1. (349 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (521 aa)
RPS6KA5Ribosomal protein S6 kinase. (838 aa)
NAIPNLR family apoptosis inhibitory protein. (1352 aa)
LRRC45Leucine rich repeat containing 45. (676 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (560 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (614 aa)
LRRC14Uncharacterized protein. (529 aa)
LRRC74BLeucine rich repeat containing 74B. (407 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (191 aa)
map2k6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
LOC100563825BZIP domain-containing protein. (341 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (615 aa)
H9GUF0_ANOCAProtein kinase domain-containing protein. (347 aa)
MAPK15Mitogen-activated protein kinase 15. (500 aa)
LOC103279342Uncharacterized protein. (553 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (69 aa)
LOC103280697NACHT domain-containing protein. (775 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (146 aa)
TANKTRAF family member associated NFKB activator. (480 aa)
H9GRS7_ANOCAUbiquitin-like domain-containing protein. (33 aa)
LRRC74ALeucine rich repeat containing 74A. (469 aa)
CCDC71LCoiled-coil domain containing 71 like. (217 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (116 aa)
H9GQH1_ANOCANACHT domain-containing protein. (619 aa)
ubcUncharacterized protein. (381 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (699 aa)
LOC100552241NACHT domain-containing protein. (1071 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (426 aa)
ATF1Activating transcription factor 1. (280 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (392 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (215 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
LRRC31Leucine rich repeat containing 31. (614 aa)
LRRC34Leucine rich repeat containing 34. (427 aa)
LRRC71Leucine rich repeat containing 71. (535 aa)
RPS6KA4Ribosomal protein S6 kinase. (766 aa)
nlrc5NACHT domain-containing protein. (531 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (141 aa)
vrk3Protein kinase domain-containing protein. (183 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (692 aa)
APPAmyloid beta precursor protein. (776 aa)
LOC100556649WRNPLPNID domain-containing protein. (938 aa)
IRF3Interferon regulatory factor 3. (450 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (841 aa)
H9GK63_ANOCAUncharacterized protein. (304 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (717 aa)
Ly96Uncharacterized protein. (47 aa)
cd14Uncharacterized protein. (456 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (761 aa)
LOC103278612Uncharacterized protein. (435 aa)
birc2Uncharacterized protein. (603 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (395 aa)
ube2nUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (679 aa)
usp18USP domain-containing protein; Belongs to the peptidase C19 family. (387 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (679 aa)
SARM1Sterile alpha and TIR motif containing 1. (708 aa)
MAPK10Mitogen-activated protein kinase. (442 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (425 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1051 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC100564881Uncharacterized protein. (549 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)
nfkbiaANK_REP_REGION domain-containing protein. (310 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
NLRX1NLR family member X1. (984 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (513 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
rps27aUbiquitin-like domain-containing protein. (156 aa)
TBK1TANK binding kinase 1. (729 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (953 aa)
FaddDeath domain-containing protein. (110 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (765 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ELK1ETS transcription factor ELK1. (439 aa)
dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (548 aa)
BIRC7Baculoviral IAP repeat containing 7. (443 aa)
N4BP1NEDD4 binding protein 1. (887 aa)
NFKB2Nuclear factor kappa B subunit 2. (924 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (937 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (400 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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