STRINGSTRING
GTF2F2 GTF2F2 flrt1 flrt1 polr2j polr2j MKNK2 MKNK2 ANOS1 ANOS1 POLR2G POLR2G mknk1 mknk1 SPRED2 SPRED2 POLR2B POLR2B PPP2CA PPP2CA POLR2H POLR2H FRS3 FRS3 FGF9 FGF9 GAB1 GAB1 PTPN11 PTPN11 NRAS NRAS PPP2CB PPP2CB CSDE1 CSDE1 rps27a rps27a ESRP1 ESRP1 NCBP1 NCBP1 PIK3CA PIK3CA POLR2D POLR2D FGFR4 FGFR4 PTBP2 PTBP2 STIL STIL FGF20 FGF20 SOS1 SOS1 LOC100567025 LOC100567025 GRB2 GRB2 polr2c polr2c FLRT2 FLRT2 FGFBP3 FGFBP3 FGF16 FGF16 FGF23 FGF23 FGF6 FGF6 ESRP2 ESRP2 FGF5 FGF5 FGF10 FGF10 BRAF BRAF FGFRL1 FGFRL1 LOC100564881 LOC100564881 FGF2 FGF2 FGF8 FGF8 LOC100567364 LOC100567364 L7MZZ4_ANOCA L7MZZ4_ANOCA FGF1 FGF1 H9GK63_ANOCA H9GK63_ANOCA POLR2A POLR2A HRAS HRAS LOC100565538 LOC100565538 POLR2F POLR2F fndc3a fndc3a POLR2L POLR2L GTF2F1 GTF2F1 FGF7 FGF7 SPRED1 SPRED1 FGF19 FGF19 SPRY2 SPRY2 FGF4 FGF4 FNDC3B FNDC3B RBFOX2 RBFOX2 FLRT3 FLRT3 KRAS KRAS TIAL1 TIAL1 PTBP3 PTBP3 LOC100559807 LOC100559807 FGFR1 FGFR1 ubc ubc POLR2K POLR2K FRS2 FRS2 FGF3 FGF3 H9GRS7_ANOCA H9GRS7_ANOCA UBA52 UBA52 FGFR2 FGFR2 FGF18 FGF18 H9GUD4_ANOCA H9GUD4_ANOCA G1KZ53_ANOCA G1KZ53_ANOCA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2F2General transcription factor IIF subunit 2. (231 aa)
flrt1Fibronectin leucine rich transmembrane protein 1. (637 aa)
polr2jRNA polymerase II subunit J. (117 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (395 aa)
ANOS1Anosmin 1. (682 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
mknk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (466 aa)
SPRED2Sprouty related EVH1 domain containing 2. (421 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
FRS3Fibroblast growth factor receptor substrate 3. (503 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
GAB1GRB2 associated binding protein 1. (746 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (513 aa)
NRASNRAS proto-oncogene, GTPase. (194 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CSDE1Cold shock domain containing E1. (796 aa)
rps27aUbiquitin-like domain-containing protein. (156 aa)
ESRP1Epithelial splicing regulatory protein 1. (684 aa)
NCBP1Nuclear cap binding protein subunit 1. (918 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
FGFR4Fibroblast growth factor receptor. (808 aa)
PTBP2Polypyrimidine tract binding protein 2. (531 aa)
STILSTIL centriolar assembly protein. (1112 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1340 aa)
LOC100567025Ig-like domain-containing protein. (152 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
polr2cRPOLD domain-containing protein. (275 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (661 aa)
FGFBP3Fibroblast growth factor binding protein 3. (238 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (188 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
ESRP2Epithelial splicing regulatory protein 2. (718 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (262 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (136 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (807 aa)
FGFRL1Fibroblast growth factor receptor like 1. (489 aa)
LOC100564881Uncharacterized protein. (549 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
LOC100567364Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1072 aa)
L7MZZ4_ANOCAUncharacterized protein. (255 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
H9GK63_ANOCAUncharacterized protein. (304 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LOC100565538Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
fndc3aUncharacterized protein. (1202 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
SPRED1Sprouty related EVH1 domain containing 1. (448 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
FNDC3BFibronectin type III domain containing 3B. (1213 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (448 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (663 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (397 aa)
PTBP3Polypyrimidine tract binding protein 3. (551 aa)
LOC100559807Uncharacterized protein. (186 aa)
FGFR1Fibroblast growth factor receptor. (821 aa)
ubcUncharacterized protein. (381 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
FRS2Fibroblast growth factor receptor substrate 2. (520 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (148 aa)
H9GRS7_ANOCAUbiquitin-like domain-containing protein. (33 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (69 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
H9GUD4_ANOCARPOLD domain-containing protein. (210 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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