STRINGSTRING
CBX4 CBX4 CETN3 CETN3 SMC5 SMC5 SMC6 SMC6 RNF2 RNF2 UBE2I UBE2I NSMCE1 NSMCE1 phc2 phc2 SUMO1 SUMO1 Nfatc2ip Nfatc2ip KCTD2 KCTD2 MEIOB MEIOB sumo2 sumo2 PARP1 PARP1 SUMO3 SUMO3 RING1 RING1 NSMCE2 NSMCE2 RECQL4 RECQL4 LOC100567594 LOC100567594 CBX2 CBX2 PIAS4 PIAS4 SEH1L SEH1L PCGF2 PCGF2 PIAS2 PIAS2 SCML2 SCML2 XRCC4 XRCC4 PHC1 PHC1 NSMCE4A NSMCE4A SCMH1 SCMH1 TDG TDG CBX8 CBX8 PHC3 PHC3 RPA1 RPA1 RNF169 RNF169 BLM BLM NUP42 NUP42 brca1 brca1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBX4Chromobox 4. (513 aa)
CETN3Centrin 3. (167 aa)
SMC5Structural maintenance of chromosomes 5. (1079 aa)
SMC6Structural maintenance of chromosomes 6. (1117 aa)
RNF2Ring finger protein 2. (336 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (232 aa)
phc2Uncharacterized protein. (291 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
Nfatc2ipUbiquitin-like domain-containing protein. (126 aa)
KCTD2Potassium channel tetramerization domain containing 2. (241 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
RING1Ring finger protein 1. (346 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (239 aa)
RECQL4RecQ like helicase 4. (1239 aa)
LOC100567594RING-type domain-containing protein. (323 aa)
CBX2Chromobox 2. (551 aa)
PIAS4Protein inhibitor of activated STAT 4. (212 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (324 aa)
PCGF2Polycomb group ring finger 2. (357 aa)
PIAS2Protein inhibitor of activated STAT 2. (601 aa)
SCML2Scm polycomb group protein like 2. (731 aa)
XRCC4X-ray repair cross complementing 4. (331 aa)
PHC1Polyhomeotic homolog 1. (1005 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (346 aa)
SCMH1Scm polycomb group protein homolog 1. (670 aa)
TDGThymine DNA glycosylase. (405 aa)
CBX8Chromobox 8. (365 aa)
PHC3Polyhomeotic homolog 3. (986 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
RNF169Ring finger protein 169. (592 aa)
BLMBLM RecQ like helicase. (1396 aa)
NUP42Nucleoporin 42. (362 aa)
brca1Uncharacterized protein. (772 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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