68 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100556675	Sema domain-containing protein; Belongs to the semaphorin family. (432 aa)
	hsp90aa1	HATPase_c domain-containing protein. (728 aa)
	LOC100561479	Uncharacterized protein; Belongs to the semaphorin family. (590 aa)
	ROCK2	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1412 aa)
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1064 aa)
	PLXNB2	Plexin B2. (1830 aa)
	pak1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	gsk3a	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1357 aa)
	DPYSL5	Dihydropyrimidinase like 5. (564 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1026 aa)
	RHOA	Ras homolog family member A. (193 aa)
	PLXNB3	Plexin B3. (1917 aa)
	LOC103281035	C-type lectin domain-containing protein. (254 aa)
	LOC100559647	Amidohydro-rel domain-containing protein. (478 aa)
	PLXNA2	Plexin A2. (1951 aa)
	LOC103280809	Sema domain-containing protein. (148 aa)
	cdk5r1	Cyclin-dependent kinase 5 activator. (328 aa)
	LOC100554656	CRIB domain-containing protein. (101 aa)
	H9GV29_ANOCA	Sema domain-containing protein. (205 aa)
	RND1	Rho family GTPase 1. (164 aa)
	LOC103283020	Sema domain-containing protein; Belongs to the semaphorin family. (263 aa)
	H9GT67_ANOCA	Uncharacterized protein. (128 aa)
	LOC100557728	Sema domain-containing protein; Belongs to the semaphorin family. (238 aa)
	H9GSC1_ANOCA	C-type lectin domain-containing protein. (368 aa)
	H9GR26_ANOCA	Uncharacterized protein. (170 aa)
	H9GQX5_ANOCA	Uncharacterized protein. (56 aa)
	H9GQ96_ANOCA	I/LWEQ domain-containing protein. (149 aa)
	rhoc	Uncharacterized protein. (193 aa)
	sema4d	Uncharacterized protein; Belongs to the semaphorin family. (722 aa)
	sema6b	PSI domain-containing protein. (372 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (776 aa)
	PAK2	Non-specific serine/threonine protein kinase. (527 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (775 aa)
	CRMP1	Collapsin response mediator protein 1. (681 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (727 aa)
	DPYSL3	Dihydropyrimidinase like 3. (682 aa)
	PLXND1	Plexin D1. (1465 aa)
	plxna4	Plexin A4. (1378 aa)
	LOC100562787	Protein kinase domain-containing protein. (304 aa)
	PAK3	Non-specific serine/threonine protein kinase. (557 aa)
	PLXNC1	Plexin C1. (680 aa)
	SEMA3G	Semaphorin 3G; Belongs to the semaphorin family. (762 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1504 aa)
	TLNRD1	Talin rod domain containing 1. (352 aa)
	TLN1	Talin 1. (2356 aa)
	RHOB	Ras homolog family member B. (197 aa)
	PLXNB1	Plexin B1. (2199 aa)
	DPYS	Dihydropyrimidinase. (505 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (762 aa)
	CFL1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1383 aa)
	SEMA4B	Uncharacterized protein. (435 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
	Sema6d	Uncharacterized protein. (435 aa)
	Cdk5r2	Uncharacterized protein. (79 aa)
	G1KDT1_ANOCA	Uncharacterized protein. (54 aa)
	LOC100552508	Uncharacterized protein. (191 aa)
	PLXNA3	Plexin A3. (1909 aa)
	DPYSL2	Dihydropyrimidinase like 2. (572 aa)
	SEMA6C	Semaphorin 6C; Belongs to the semaphorin family. (432 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1269 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (912 aa)
	LIMK1	LIM domain kinase 1. (557 aa)
	plxna1	Plexin A1. (1886 aa)
	DPYSL4	Dihydropyrimidinase like 4. (672 aa)
	TLN2	Uncharacterized protein. (2256 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	LOC100552508	ENSACAP00000011409	ENSACAP00000005135	Rho GTPase activating protein 35.	Uncharacterized protein.	0.754
ARHGAP35	LOC103280809	ENSACAP00000011409	ENSACAP00000021489	Rho GTPase activating protein 35.	Sema domain-containing protein.	0.445
ARHGAP35	MET	ENSACAP00000011409	ENSACAP00000008564	Rho GTPase activating protein 35.	MET proto-oncogene, receptor tyrosine kinase.	0.700
ARHGAP35	PLXNB1	ENSACAP00000011409	ENSACAP00000010358	Rho GTPase activating protein 35.	Plexin B1.	0.424
ARHGAP35	PLXNB2	ENSACAP00000011409	ENSACAP00000001690	Rho GTPase activating protein 35.	Plexin B2.	0.424
ARHGAP35	PLXNB3	ENSACAP00000011409	ENSACAP00000008335	Rho GTPase activating protein 35.	Plexin B3.	0.424
ARHGAP35	RHOA	ENSACAP00000011409	ENSACAP00000008136	Rho GTPase activating protein 35.	Ras homolog family member A.	0.974
ARHGAP35	RHOB	ENSACAP00000011409	ENSACAP00000010462	Rho GTPase activating protein 35.	Ras homolog family member B.	0.754
ARHGAP35	RND1	ENSACAP00000011409	ENSACAP00000020819	Rho GTPase activating protein 35.	Rho family GTPase 1.	0.856
ARHGAP35	ROCK1	ENSACAP00000011409	ENSACAP00000008028	Rho GTPase activating protein 35.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.402
ARHGAP35	rhoc	ENSACAP00000011409	ENSACAP00000017665	Rho GTPase activating protein 35.	Uncharacterized protein.	0.754
ARHGAP35	sema4d	ENSACAP00000011409	ENSACAP00000016373	Rho GTPase activating protein 35.	Uncharacterized protein; Belongs to the semaphorin family.	0.445
CFL1	CFL2	ENSACAP00000008582	ENSACAP00000002287	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.404
CFL1	LIMK1	ENSACAP00000008582	ENSACAP00000007341	Cofilin 1; Belongs to the actin-binding proteins ADF family.	LIM domain kinase 1.	0.936
CFL1	LOC100562787	ENSACAP00000008582	ENSACAP00000013059	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Protein kinase domain-containing protein.	0.712
CFL2	CFL1	ENSACAP00000002287	ENSACAP00000008582	Cofilin 2; Belongs to the actin-binding proteins ADF family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.404
CFL2	LIMK1	ENSACAP00000002287	ENSACAP00000007341	Cofilin 2; Belongs to the actin-binding proteins ADF family.	LIM domain kinase 1.	0.991
CFL2	LOC100562787	ENSACAP00000002287	ENSACAP00000013059	Cofilin 2; Belongs to the actin-binding proteins ADF family.	Protein kinase domain-containing protein.	0.712
CFL2	RHOA	ENSACAP00000002287	ENSACAP00000008136	Cofilin 2; Belongs to the actin-binding proteins ADF family.	Ras homolog family member A.	0.482
CFL2	ROCK1	ENSACAP00000002287	ENSACAP00000008028	Cofilin 2; Belongs to the actin-binding proteins ADF family.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.501