STRINGSTRING
POLR2L POLR2L ERCC4 ERCC4 UBE2I UBE2I RCBTB2 RCBTB2 rps27a rps27a DDB2 DDB2 bivm bivm LOC107982244 LOC107982244 POLR2H POLR2H PPIE PPIE LOC100554464 LOC100554464 POLR2B POLR2B LOC103282877 LOC103282877 RPAP3 RPAP3 TCEANC TCEANC AQR AQR POLR2G POLR2G POLE2 POLE2 RFC2 RFC2 CCNH CCNH ino80b ino80b WBP1 WBP1 PCNA PCNA CUL4A CUL4A polr2j polr2j CETN3 CETN3 GTF2H1 GTF2H1 MNAT1 MNAT1 tcea2 tcea2 PARP1 PARP1 sumo2 sumo2 MEIOB MEIOB KCTD2 KCTD2 COPS7A COPS7A USP7 USP7 Nfatc2ip Nfatc2ip HMGN1 HMGN1 POLR2D POLR2D RBX1 RBX1 EP300 EP300 SUMO1 SUMO1 TCEA3 TCEA3 GTF2H5 GTF2H5 COPS3 COPS3 XPA XPA xrcc1 xrcc1 INO80D INO80D RFC3 RFC3 RAD23B RAD23B INO80 INO80 RNF111 RNF111 NFRKB NFRKB CHD1L CHD1L DDB1 DDB1 PRPF19 PRPF19 TCEA1 TCEA1 ubc ubc hmgn2 hmgn2 POLR2K POLR2K COPS7B COPS7B UBE2V2 UBE2V2 cops6 cops6 ube2n ube2n RPA3 RPA3 isy1 isy1 YY1 YY1 XPC XPC H9GK63_ANOCA H9GK63_ANOCA PIAS3 PIAS3 RCBTB1 RCBTB1 TCEANC2 TCEANC2 ACTR5 ACTR5 pold3 pold3 NRDE2 NRDE2 RPA1 RPA1 POLR2A POLR2A RUVBL1 RUVBL1 polr2c polr2c RFC1 RFC1 RFC4 RFC4 LOC100567089 LOC100567089 SUMO3 SUMO3 PARP2 PARP2 H9GRS7_ANOCA H9GRS7_ANOCA UBA52 UBA52 ATAD5 ATAD5 LOC100561391 LOC100561391 H9GT41_ANOCA H9GT41_ANOCA H9GT97_ANOCA H9GT97_ANOCA POLD1 POLD1 LOC100559702 LOC100559702 H9GUD4_ANOCA H9GUD4_ANOCA spocd1 spocd1 G1KZ53_ANOCA G1KZ53_ANOCA H9GVV6_ANOCA H9GVV6_ANOCA ercc1 ercc1 XAB2 XAB2 rad23a rad23a H9GNG7_ANOCA H9GNG7_ANOCA RFC5 RFC5 CDK7 CDK7 PPP1R42 PPP1R42 COPS5 COPS5 TFPT TFPT COPS2 COPS2 wdr76 wdr76 POLR2F POLR2F GTF2H3 GTF2H3 POLK POLK VWA5B2 VWA5B2 ERCC8 ERCC8 PHF3 PHF3 ZNF830 ZNF830 USP40 USP40 INO80C INO80C ERCC3 ERCC3 GPS1 GPS1 uvssa uvssa LOC100558064 LOC100558064 INO80E INO80E PIAS1 PIAS1 GTF2H4 GTF2H4 mcrs1 mcrs1 USP45 USP45 COPS8 COPS8 POLE POLE COPS4 COPS4 CUL4B CUL4B LIG1 LIG1 PARP3 PARP3 ERCC6 ERCC6 POLD2 POLD2 ACTR8 ACTR8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2LRNA polymerase II subunit L. (67 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (842 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (554 aa)
rps27aUbiquitin-like domain-containing protein. (156 aa)
DDB2Damage specific DNA binding protein 2. (552 aa)
bivmUncharacterized protein. (501 aa)
LOC107982244Uncharacterized protein. (1108 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
LOC100554464FHA domain-containing protein. (118 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
LOC103282877Uncharacterized protein. (228 aa)
RPAP3RNA polymerase II associated protein 3. (739 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (309 aa)
AQRAquarius intron-binding spliceosomal factor. (1482 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
RFC2Replication factor C subunit 2. (318 aa)
CCNHCyclin H; Belongs to the cyclin family. (318 aa)
ino80bPAPA-1 domain-containing protein. (311 aa)
WBP1WW domain binding protein 1. (341 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CUL4ACullin 4A; Belongs to the cullin family. (765 aa)
polr2jRNA polymerase II subunit J. (117 aa)
CETN3Centrin 3. (167 aa)
GTF2H1General transcription factor IIH subunit 1. (571 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
tcea2Uncharacterized protein. (302 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
KCTD2Potassium channel tetramerization domain containing 2. (241 aa)
COPS7ACOP9 signalosome subunit 7A. (303 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1094 aa)
Nfatc2ipUbiquitin-like domain-containing protein. (126 aa)
HMGN1High mobility group nucleosome binding domain 1. (98 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
RBX1Ring-box 1. (108 aa)
EP300E1A binding protein p300. (2484 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
TCEA3Transcription elongation factor A3. (329 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
COPS3COP9 signalosome subunit 3. (451 aa)
XPAXPA, DNA damage recognition and repair factor. (280 aa)
xrcc1Uncharacterized protein. (656 aa)
INO80DINO80 complex subunit D. (1042 aa)
RFC3Replication factor C subunit 3. (356 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (425 aa)
INO80INO80 complex ATPase subunit. (1421 aa)
RNF111Ring finger protein 111. (509 aa)
NFRKBNuclear factor related to kappaB binding protein. (1335 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (904 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
TCEA1Transcription elongation factor A1. (305 aa)
ubcUncharacterized protein. (381 aa)
hmgn2Uncharacterized protein. (90 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
COPS7BCOP9 signalosome subunit 7B. (264 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (147 aa)
cops6MitMem_reg domain-containing protein. (150 aa)
ube2nUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RPA3Replication protein A3. (121 aa)
isy1Uncharacterized protein. (257 aa)
YY1YY1 transcription factor. (189 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (960 aa)
H9GK63_ANOCAUncharacterized protein. (304 aa)
PIAS3Protein inhibitor of activated STAT 3. (703 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (530 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (208 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (619 aa)
pold3Uncharacterized protein. (428 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1165 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
polr2cRPOLD domain-containing protein. (275 aa)
RFC1Replication factor C subunit 1. (1146 aa)
RFC4Replication factor C subunit 4. (364 aa)
LOC100567089Uncharacterized protein. (817 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
PARP2Poly [ADP-ribose] polymerase. (566 aa)
H9GRS7_ANOCAUbiquitin-like domain-containing protein. (33 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (69 aa)
ATAD5ATPase family AAA domain containing 5. (1748 aa)
LOC100561391WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (434 aa)
H9GT41_ANOCAUncharacterized protein. (189 aa)
H9GT97_ANOCAUncharacterized protein. (182 aa)
POLD1DNA polymerase. (1113 aa)
LOC100559702Uncharacterized protein. (117 aa)
H9GUD4_ANOCARPOLD domain-containing protein. (210 aa)
spocd1TFIIS central domain-containing protein. (541 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
H9GVV6_ANOCAUncharacterized protein. (31 aa)
ercc1Uncharacterized protein. (297 aa)
XAB2XPA binding protein 2. (922 aa)
rad23aUncharacterized protein. (365 aa)
H9GNG7_ANOCAMitMem_reg domain-containing protein. (229 aa)
RFC5Replication factor C subunit 5. (342 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (345 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (376 aa)
COPS5COP9 signalosome subunit 5. (293 aa)
TFPTTCF3 fusion partner. (245 aa)
COPS2COP9 signalosome subunit 2. (507 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (466 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
GTF2H3General transcription factor IIH subunit 3. (311 aa)
POLKDNA polymerase kappa. (838 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1279 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (354 aa)
PHF3PHD finger protein 3. (2036 aa)
ZNF830Zinc finger protein 830. (376 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1234 aa)
INO80CINO80 complex subunit C. (191 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (719 aa)
GPS1G protein pathway suppressor 1. (527 aa)
uvssaUncharacterized protein. (735 aa)
LOC100558064General transcription factor IIH subunit. (392 aa)
INO80EINO80 complex subunit E. (253 aa)
PIAS1Protein inhibitor of activated STAT 1. (661 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
mcrs1FHA domain-containing protein. (449 aa)
USP45Ubiquitin carboxyl-terminal hydrolase. (813 aa)
COPS8COP9 signalosome subunit 8. (212 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2291 aa)
COPS4COP9 signalosome subunit 4. (194 aa)
CUL4BCullin 4B; Belongs to the cullin family. (898 aa)
LIG1DNA ligase. (913 aa)
PARP3Poly [ADP-ribose] polymerase. (542 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1440 aa)
POLD2DNA polymerase delta 2, accessory subunit. (473 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (641 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (16%) [HD]