49 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	POLR2F	RNA polymerase II subunit F. (127 aa)
	SNRNP35	Small nuclear ribonucleoprotein U11/U12 subunit 35. (260 aa)
	POLR2L	RNA polymerase II subunit L. (67 aa)
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
	SNRNP25	Small nuclear ribonucleoprotein U11/U12 subunit 25. (151 aa)
	SNRPD2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	ZRSR2	Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (463 aa)
	POLR2K	RNA polymerase II subunit K. (58 aa)
	H9GUD4_ANOCA	RPOLD domain-containing protein. (210 aa)
	DDX23	DEAD-box helicase 23. (851 aa)
	G1KZ53_ANOCA	Uncharacterized protein. (236 aa)
	GTF2F2	General transcription factor IIF subunit 2. (231 aa)
	LOC100551580	Thioredoxin-like protein 4A. (142 aa)
	LOC100565538	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa)
	PRPF8	Pre-mRNA processing factor 8. (1941 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
	SNRPF	Small nuclear ribonucleoprotein polypeptide F. (87 aa)
	SF3B6	Splicing factor 3b subunit 6. (125 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	SF3B4	Splicing factor 3b subunit 4. (417 aa)
	SF3B1	Splicing factor 3b subunit 1. (1302 aa)
	SF3B2	Splicing factor 3b subunit 2. (886 aa)
	SF3B5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	SNRPG	Small nuclear ribonucleoprotein G. (76 aa)
	EFTUD2	Elongation factor Tu GTP binding domain containing 2. (972 aa)
	polr2c	RPOLD domain-containing protein. (275 aa)
	PRPF6	Pre-mRNA processing factor 6. (988 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	SRSF7	Serine and arginine rich splicing factor 7. (235 aa)
	srsf1	Uncharacterized protein. (247 aa)
	POLR2D	RNA polymerase II subunit D. (142 aa)
	PDCD7	Programmed cell death 7. (244 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (918 aa)
	DDX42	DEAD-box helicase 42. (933 aa)
	SNRPD3	Small nuclear ribonucleoprotein D3 polypeptide. (94 aa)
	ZCRB1	Zinc finger CCHC-type and RNA binding motif containing 1. (216 aa)
	polr2j	RNA polymerase II subunit J. (117 aa)
	SNRNP200	Small nuclear ribonucleoprotein U5 subunit 200. (1718 aa)
	SNRNP40	Small nuclear ribonucleoprotein U5 subunit 40. (359 aa)
	ZMAT5	Zinc finger matrin-type 5. (131 aa)
	LOC103282740	Y-box binding protein 2. (165 aa)
	POLR2G	RNA polymerase II subunit G. (172 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	SF3B3	Splicing factor 3b subunit 3. (1217 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein. (232 aa)
	RNPC3	RNA binding region (RNP1, RRM) containing 3. (506 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	SNRNP48	Small nuclear ribonucleoprotein U11/U12 subunit 48. (317 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX23	EFTUD2	ENSACAP00000021105	ENSACAP00000007670	DEAD-box helicase 23.	Elongation factor Tu GTP binding domain containing 2.	0.997
DDX23	LOC100551580	ENSACAP00000021105	ENSACAP00000022714	DEAD-box helicase 23.	Thioredoxin-like protein 4A.	0.950
DDX23	LOC100565538	ENSACAP00000021105	ENSACAP00000014847	DEAD-box helicase 23.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.521
DDX23	NCBP1	ENSACAP00000021105	ENSACAP00000004405	DEAD-box helicase 23.	Nuclear cap binding protein subunit 1.	0.591
DDX23	PRPF6	ENSACAP00000021105	ENSACAP00000006435	DEAD-box helicase 23.	Pre-mRNA processing factor 6.	0.996
DDX23	PRPF8	ENSACAP00000021105	ENSACAP00000014503	DEAD-box helicase 23.	Pre-mRNA processing factor 8.	0.999
DDX23	RNPC3	ENSACAP00000021105	ENSACAP00000002052	DEAD-box helicase 23.	RNA binding region (RNP1, RRM) containing 3.	0.569
DDX23	SF3B1	ENSACAP00000021105	ENSACAP00000009477	DEAD-box helicase 23.	Splicing factor 3b subunit 1.	0.876
DDX23	SF3B2	ENSACAP00000021105	ENSACAP00000008437	DEAD-box helicase 23.	Splicing factor 3b subunit 2.	0.842
DDX23	SF3B3	ENSACAP00000021105	ENSACAP00000001863	DEAD-box helicase 23.	Splicing factor 3b subunit 3.	0.851
DDX23	SF3B4	ENSACAP00000021105	ENSACAP00000009831	DEAD-box helicase 23.	Splicing factor 3b subunit 4.	0.801
DDX23	SF3B5	ENSACAP00000021105	ENSACAP00000007768	DEAD-box helicase 23.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.693
DDX23	SF3B6	ENSACAP00000021105	ENSACAP00000011406	DEAD-box helicase 23.	Splicing factor 3b subunit 6.	0.630
DDX23	SNRNP200	ENSACAP00000021105	ENSACAP00000000445	DEAD-box helicase 23.	Small nuclear ribonucleoprotein U5 subunit 200.	0.991
DDX23	SNRNP35	ENSACAP00000021105	ENSACAP00000015140	DEAD-box helicase 23.	Small nuclear ribonucleoprotein U11/U12 subunit 35.	0.833
DDX23	SNRNP40	ENSACAP00000021105	ENSACAP00000000505	DEAD-box helicase 23.	Small nuclear ribonucleoprotein U5 subunit 40.	0.993
DDX23	SNRPB	ENSACAP00000021105	ENSACAP00000002014	DEAD-box helicase 23.	Small nuclear ribonucleoprotein-associated protein.	0.930
DDX23	SNRPD1	ENSACAP00000021105	ENSACAP00000006209	DEAD-box helicase 23.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.979
DDX23	SNRPD2	ENSACAP00000021105	ENSACAP00000016502	DEAD-box helicase 23.	Small nuclear ribonucleoprotein Sm D2.	0.990
DDX23	SNRPD3	ENSACAP00000021105	ENSACAP00000003218	DEAD-box helicase 23.	Small nuclear ribonucleoprotein D3 polypeptide.	0.986