STRINGSTRING
GNG2 GNG2 hsp90aa1 hsp90aa1 polr2j polr2j GREB1 GREB1 LOC103282369 LOC103282369 TBPL1 TBPL1 NCOA1 NCOA1 tbpl2 tbpl2 POLR2G POLR2G ZC3H12C ZC3H12C ddx5 ddx5 NRIP1 NRIP1 FOXA1 FOXA1 GNG4 GNG4 CXXC5 CXXC5 POLR2B POLR2B KANK1 KANK1 EBAG9 EBAG9 XPO1 XPO1 tbp tbp POLR2H POLR2H AKT2 AKT2 NRAS NRAS GTF2A2 GTF2A2 LOC100566534 LOC100566534 CSDE1 CSDE1 LOC100556472 LOC100556472 LOC100556079 LOC100556079 G1KBW3_ANOCA G1KBW3_ANOCA Wdr64 Wdr64 PDPK1 PDPK1 LOC100562262 LOC100562262 LOC100552683 LOC100552683 HIST1H4J HIST1H4J LOC100553081 LOC100553081 Kank2 Kank2 LOC100553870 LOC100553870 GNB4 GNB4 ELK1 ELK1 PRMT1 PRMT1 PIK3CA PIK3CA LOC103278423 LOC103278423 EP300 EP300 GNB1 GNB1 POLR2D POLR2D LOC100561800 LOC100561800 GNG5 GNG5 GNB3 GNB3 H2AZ2 H2AZ2 esr1 esr1 CAV1 CAV1 CAV2 CAV2 AKT3 AKT3 CDK9 CDK9 ZC3H12D ZC3H12D polr2c polr2c KANK4 KANK4 GREB1L GREB1L GNG8 GNG8 CCNT1 CCNT1 GATA3 GATA3 PTGES3 PTGES3 PRMT8 PRMT8 CREB1 CREB1 MYB MYB EGF EGF USF2 USF2 Pik3r2 Pik3r2 H9GGQ9_ANOCA H9GGQ9_ANOCA GNB5 GNB5 TRPS1 TRPS1 EREG EREG AKT1 AKT1 LOC100562999 LOC100562999 CAV3 CAV3 STRN4 STRN4 LOC100567364 LOC100567364 H2AZ1 H2AZ1 LOC100553835 LOC100553835 GNG10 GNG10 CREBBP CREBBP ZNF217 ZNF217 pik3r2 pik3r2 CBFB CBFB GNG11 GNG11 YY1 YY1 aarsd1 aarsd1 ZC3H12B ZC3H12B PGR PGR ZDHHC7 ZDHHC7 POLR2A POLR2A HSP90AB1 HSP90AB1 HRAS HRAS STRN3 STRN3 NCOA2 NCOA2 FKBP4 FKBP4 LOC100557042 LOC100557042 POLR2F POLR2F LOC100557833 LOC100557833 LOC100558030 LOC100558030 CARM1 CARM1 LOC100558489 LOC100558489 ENSACAP00000015206 ENSACAP00000015206 POLR2L POLR2L GTF2F1 GTF2F1 ESR2 ESR2 pik3r3 pik3r3 PIK3R1 PIK3R1 LOC100566791 LOC100566791 NCOA3 NCOA3 PPID PPID S1PR3 S1PR3 G1KSV5_ANOCA G1KSV5_ANOCA PPP5C PPP5C KRAS KRAS KDM1A KDM1A FKBP5 FKBP5 ZC3H12A ZC3H12A LOC100559807 LOC100559807 GTF2A1 GTF2A1 ZDHHC21 ZDHHC21 LOC100559083 LOC100559083 POLR2K POLR2K LOC100556861 LOC100556861 LOC100553635 LOC100553635 EPGN EPGN ENSACAP00000019009 ENSACAP00000019009 ENSACAP00000019109 ENSACAP00000019109 H9GRZ9_ANOCA H9GRZ9_ANOCA H9GSU7_ANOCA H9GSU7_ANOCA H9GT67_ANOCA H9GT67_ANOCA H9GUD4_ANOCA H9GUD4_ANOCA GNGT2 GNGT2 G1KYA2_ANOCA G1KYA2_ANOCA G1KZ53_ANOCA G1KZ53_ANOCA H9GVQ7_ANOCA H9GVQ7_ANOCA LOC100557254 LOC100557254 H9GVV6_ANOCA H9GVV6_ANOCA HBEGF HBEGF GTF2F2 GTF2F2 AREG AREG STRN STRN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
hsp90aa1HATPase_c domain-containing protein. (728 aa)
polr2jRNA polymerase II subunit J. (117 aa)
GREB1Uncharacterized protein. (1933 aa)
LOC103282369PG_binding_1 domain-containing protein. (128 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
NCOA1Nuclear receptor coactivator. (1466 aa)
tbpl2Uncharacterized protein. (192 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (905 aa)
ddx5Uncharacterized protein; Belongs to the DEAD box helicase family. (600 aa)
NRIP1Nuclear receptor interacting protein 1. (1170 aa)
FOXA1Forkhead box A1. (487 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CXXC5CXXC finger protein 5. (275 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
KANK1KN motif and ankyrin repeat domains 1. (1344 aa)
EBAG9Estrogen receptor binding site associated antigen 9; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
XPO1Exportin 1. (1071 aa)
tbpUncharacterized protein. (300 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NRASNRAS proto-oncogene, GTPase. (194 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (88 aa)
LOC100566534CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (453 aa)
CSDE1Cold shock domain containing E1. (796 aa)
LOC100556472Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100556079Histone H2B; Belongs to the histone H2B family. (126 aa)
G1KBW3_ANOCAWD_REPEATS_REGION domain-containing protein. (462 aa)
Wdr64Uncharacterized protein. (363 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (546 aa)
LOC100562262WD_REPEATS_REGION domain-containing protein. (203 aa)
LOC100552683Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST1H4JHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100553081Histone H2B 5-like. (126 aa)
Kank2ANK_REP_REGION domain-containing protein. (89 aa)
LOC100553870Histone H4. (103 aa)
GNB4G protein subunit beta 4. (340 aa)
ELK1ETS transcription factor ELK1. (439 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (370 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC103278423WD_REPEATS_REGION domain-containing protein. (146 aa)
EP300E1A binding protein p300. (2484 aa)
GNB1G protein subunit beta 1. (333 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
LOC100561800Protein kinase domain-containing protein. (252 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GNB3G protein subunit beta 3. (340 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (642 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CDK9Cyclin dependent kinase 9. (197 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (323 aa)
polr2cRPOLD domain-containing protein. (275 aa)
KANK4KN motif and ankyrin repeat domains 4. (1008 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1970 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (722 aa)
GATA3GATA binding protein 3. (365 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (395 aa)
CREB1cAMP responsive element binding protein 1. (349 aa)
MYBMYB proto-oncogene, transcription factor. (641 aa)
EGFEpidermal growth factor. (1049 aa)
USF2Upstream transcription factor 2, c-fos interacting. (346 aa)
Pik3r2Uncharacterized protein. (215 aa)
H9GGQ9_ANOCAUncharacterized protein. (95 aa)
GNB5G protein subunit beta 5. (395 aa)
TRPS1Transcriptional repressor GATA binding 1. (1281 aa)
EREGEpiregulin. (167 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC100562999Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (157 aa)
STRN4Striatin 4. (754 aa)
LOC100567364Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1072 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC100553835ZnMc domain-containing protein. (265 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREBBPCREB binding protein. (2444 aa)
ZNF217Zinc finger protein 217. (1054 aa)
pik3r2Uncharacterized protein. (305 aa)
CBFBCore-binding factor subunit beta. (187 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
YY1YY1 transcription factor. (189 aa)
aarsd1Uncharacterized protein. (542 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (835 aa)
PGRProgesterone receptor. (387 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (727 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
STRN3Striatin 3. (814 aa)
NCOA2Nuclear receptor coactivator. (1459 aa)
FKBP4Peptidylprolyl isomerase. (372 aa)
LOC100557042Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
LOC100557833Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100558030Histone H4. (103 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
LOC100558489Histone H4. (103 aa)
ENSACAP00000015206annotation not available (103 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
ESR2Estrogen receptor 2. (555 aa)
pik3r3Uncharacterized protein. (473 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC100566791Uncharacterized protein. (166 aa)
NCOA3Nuclear receptor coactivator. (1398 aa)
PPIDPeptidylprolyl isomerase D. (374 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (371 aa)
G1KSV5_ANOCAANK_REP_REGION domain-containing protein. (1197 aa)
PPP5CSerine/threonine-protein phosphatase. (503 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
FKBP5Peptidylprolyl isomerase. (456 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (609 aa)
LOC100559807Uncharacterized protein. (186 aa)
GTF2A1General transcription factor IIA subunit 1. (383 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
LOC100559083Histone H4. (103 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
LOC100556861Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100553635ZnMc domain-containing protein. (256 aa)
EPGNEpithelial mitogen. (153 aa)
ENSACAP00000019009annotation not available (103 aa)
ENSACAP00000019109annotation not available (103 aa)
H9GRZ9_ANOCAUncharacterized protein. (583 aa)
H9GSU7_ANOCARRM domain-containing protein. (392 aa)
H9GT67_ANOCAUncharacterized protein. (128 aa)
H9GUD4_ANOCARPOLD domain-containing protein. (210 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
G1KYA2_ANOCAP-type domain-containing protein. (45 aa)
G1KZ53_ANOCAUncharacterized protein. (236 aa)
H9GVQ7_ANOCAWD_REPEATS_REGION domain-containing protein. (92 aa)
LOC100557254Histone H2B; Belongs to the histone H2B family. (126 aa)
H9GVV6_ANOCAUncharacterized protein. (31 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
GTF2F2General transcription factor IIF subunit 2. (231 aa)
AREGAmphiregulin. (175 aa)
STRNStriatin. (843 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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