82 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100559083	Histone H4. (103 aa)
	POLR2K	RNA polymerase II subunit K. (58 aa)
	LOC100556861	Histone H2B; Belongs to the histone H2B family. (126 aa)
	ENSACAP00000019009	annotation not available (103 aa)
	GTF2F2	General transcription factor IIF subunit 2. (231 aa)
	H9GVV6_ANOCA	Uncharacterized protein. (31 aa)
	LOC100557254	Histone H2B; Belongs to the histone H2B family. (126 aa)
	G1KZ53_ANOCA	Uncharacterized protein. (236 aa)
	G1KYA2_ANOCA	P-type domain-containing protein. (45 aa)
	H9GUD4_ANOCA	RPOLD domain-containing protein. (210 aa)
	H9GT67_ANOCA	Uncharacterized protein. (128 aa)
	H9GRZ9_ANOCA	Uncharacterized protein. (583 aa)
	MYB	MYB proto-oncogene, transcription factor. (641 aa)
	USF2	Upstream transcription factor 2, c-fos interacting. (346 aa)
	TRPS1	Transcriptional repressor GATA binding 1. (1281 aa)
	H2AZ1	Histone H2A; Belongs to the histone H2A family. (128 aa)
	CREBBP	CREB binding protein. (2444 aa)
	ZNF217	Zinc finger protein 217. (1054 aa)
	CBFB	Core-binding factor subunit beta. (187 aa)
	YY1	YY1 transcription factor. (189 aa)
	ZC3H12B	Zinc finger CCCH-type containing 12B. (835 aa)
	PGR	Progesterone receptor. (387 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (727 aa)
	NCOA2	Nuclear receptor coactivator. (1459 aa)
	FKBP4	Peptidylprolyl isomerase. (372 aa)
	ENSACAP00000019109	annotation not available (103 aa)
	LOC100557042	Histone H2B; Belongs to the histone H2B family. (126 aa)
	POLR2F	RNA polymerase II subunit F. (127 aa)
	LOC100557833	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC100558030	Histone H4. (103 aa)
	CARM1	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
	LOC100558489	Histone H4. (103 aa)
	ENSACAP00000015206	annotation not available (103 aa)
	POLR2L	RNA polymerase II subunit L. (67 aa)
	hsp90aa1	HATPase_c domain-containing protein. (728 aa)
	polr2j	RNA polymerase II subunit J. (117 aa)
	GREB1	Uncharacterized protein. (1933 aa)
	TBPL1	TATA-box binding protein like 1. (186 aa)
	NCOA1	Nuclear receptor coactivator. (1466 aa)
	tbpl2	Uncharacterized protein. (192 aa)
	POLR2G	RNA polymerase II subunit G. (172 aa)
	ZC3H12C	Zinc finger CCCH-type containing 12C. (905 aa)
	ddx5	Uncharacterized protein; Belongs to the DEAD box helicase family. (600 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1170 aa)
	FOXA1	Forkhead box A1. (487 aa)
	CXXC5	CXXC finger protein 5. (275 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1344 aa)
	EBAG9	Estrogen receptor binding site associated antigen 9; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
	tbp	Uncharacterized protein. (300 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (88 aa)
	LOC100566534	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (453 aa)
	LOC100556472	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC100556079	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC100552683	Histone H2B; Belongs to the histone H2B family. (126 aa)
	HIST1H4J	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	LOC100553081	Histone H2B 5-like. (126 aa)
	Kank2	ANK_REP_REGION domain-containing protein. (89 aa)
	LOC100553870	Histone H4. (103 aa)
	PRMT1	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (370 aa)
	EP300	E1A binding protein p300. (2484 aa)
	POLR2D	RNA polymerase II subunit D. (142 aa)
	H2AZ2	Histone H2A; Belongs to the histone H2A family. (128 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (642 aa)
	CDK9	Cyclin dependent kinase 9. (197 aa)
	ZC3H12D	Zinc finger CCCH-type containing 12D. (323 aa)
	polr2c	RPOLD domain-containing protein. (275 aa)
	KANK4	KN motif and ankyrin repeat domains 4. (1008 aa)
	GREB1L	GREB1 like retinoic acid receptor coactivator. (1970 aa)
	CCNT1	Cyclin T1; Belongs to the cyclin family. (722 aa)
	GATA3	GATA binding protein 3. (365 aa)
	PTGES3	Prostaglandin E synthase 3. (160 aa)
	PRMT8	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (395 aa)
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
	LOC100566791	Uncharacterized protein. (166 aa)
	NCOA3	Nuclear receptor coactivator. (1398 aa)
	G1KSV5_ANOCA	ANK_REP_REGION domain-containing protein. (1197 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (609 aa)
	GTF2A1	General transcription factor IIA subunit 1. (383 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARM1	CREBBP	ENSACAP00000015102	ENSACAP00000012418	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	CREB binding protein.	0.793
CARM1	EP300	ENSACAP00000015102	ENSACAP00000005074	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	E1A binding protein p300.	0.864
CARM1	FOXA1	ENSACAP00000015102	ENSACAP00000001204	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Forkhead box A1.	0.578
CARM1	GATA3	ENSACAP00000015102	ENSACAP00000008932	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 3.	0.449
CARM1	H9GRZ9_ANOCA	ENSACAP00000015102	ENSACAP00000019121	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.405
CARM1	Kank2	ENSACAP00000015102	ENSACAP00000004348	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	ANK_REP_REGION domain-containing protein.	0.432
CARM1	NCOA1	ENSACAP00000015102	ENSACAP00000000770	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.600
CARM1	NCOA2	ENSACAP00000015102	ENSACAP00000014888	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.600
CARM1	NCOA3	ENSACAP00000015102	ENSACAP00000016172	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.600
CARM1	PRMT1	ENSACAP00000015102	ENSACAP00000004792	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.748
CARM1	PRMT8	ENSACAP00000015102	ENSACAP00000009131	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.559
CARM1	ddx5	ENSACAP00000015102	ENSACAP00000001000	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.405
CARM1	esr1	ENSACAP00000015102	ENSACAP00000006106	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily.	0.508
CARM1	tbp	ENSACAP00000015102	ENSACAP00000002524	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.464
CBFB	CREBBP	ENSACAP00000012976	ENSACAP00000012418	Core-binding factor subunit beta.	CREB binding protein.	0.606
CBFB	EP300	ENSACAP00000012976	ENSACAP00000005074	Core-binding factor subunit beta.	E1A binding protein p300.	0.646
CBFB	GATA3	ENSACAP00000012976	ENSACAP00000008932	Core-binding factor subunit beta.	GATA binding protein 3.	0.680
CBFB	PRMT1	ENSACAP00000012976	ENSACAP00000004792	Core-binding factor subunit beta.	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.680
CBFB	PRMT8	ENSACAP00000012976	ENSACAP00000009131	Core-binding factor subunit beta.	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.587
CBFB	TRPS1	ENSACAP00000012976	ENSACAP00000010955	Core-binding factor subunit beta.	Transcriptional repressor GATA binding 1.	0.456