STRINGSTRING
SHH SHH CCND1 CCND1 GLI3 GLI3 SMO SMO FOXO6 FOXO6 GLI2 GLI2 HDAC6 HDAC6 FOXJ1 FOXJ1 PTCH1 PTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
CCND1Cyclin D1. (154 aa)
GLI3GLI family zinc finger 3. (1489 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
FOXO6Forkhead box O6. (484 aa)
GLI2GLI family zinc finger 2. (1284 aa)
HDAC6Histone deacetylase 6. (1204 aa)
FOXJ1Forkhead box J1. (427 aa)
PTCH1Patched 1. (1047 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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