STRINGSTRING
ACE2 ACE2 ADAMTS3 ADAMTS3 ace ace PLAT PLAT VEGFD VEGFD FAT4 FAT4 pdgfra pdgfra HDGF HDGF ADAMTS14 ADAMTS14 CCBE1 CCBE1 NRP1 NRP1 VEGFC VEGFC FURIN FURIN PLG PLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACE2Angiotensin-converting enzyme. (814 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1203 aa)
aceAngiotensin-converting enzyme. (1305 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (555 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
pdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
HDGFHeparin binding growth factor. (221 aa)
ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif 14. (1096 aa)
CCBE1Collagen and calcium binding EGF domains 1. (381 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (912 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (424 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (885 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (801 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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