STRINGSTRING
HDGF HDGF CFL1 CFL1 VDAC2 VDAC2 CLUL1 CLUL1 CTNNA2 CTNNA2 LOC100559227 LOC100559227 KCND2 KCND2 CNTF CNTF KCNK3 KCNK3 GAPDH GAPDH PSEN2 PSEN2 PARP1 PARP1 TPI1 TPI1 BCAN BCAN sod2 sod2 LOC100555140 LOC100555140 ARL3 ARL3 NOVA2 NOVA2 ptprm ptprm VLDLR VLDLR RTN3 RTN3 EGLN3 EGLN3 GRIA3 GRIA3 NPTX2 NPTX2 BACE1 BACE1 MTOR MTOR PCNA PCNA SNCA SNCA KCNE2 KCNE2 EGR1 EGR1 CACNG8 CACNG8 TGFB1 TGFB1 CKS2 CKS2 CTNNA1 CTNNA1 CCND1 CCND1 AURKA AURKA CD36 CD36 BDNF BDNF RTN1 RTN1 CTSB CTSB PCDH1 PCDH1 DGAT1 DGAT1 TIE1 TIE1 SYP SYP RTN4 RTN4 PDHB PDHB LOC100552932 LOC100552932 NEFL NEFL C9orf72 C9orf72 CLU CLU CTNNA3 CTNNA3 RICTOR RICTOR IDH1 IDH1 IDH2 IDH2 UCP3 UCP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDGFHeparin binding growth factor. (221 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
VDAC2Voltage dependent anion channel 2. (298 aa)
CLUL1Clusterin; Belongs to the clusterin family. (459 aa)
CTNNA2Uncharacterized protein. (554 aa)
LOC100559227Reticulon. (190 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
CNTFCiliary neurotrophic factor. (200 aa)
KCNK3Potassium two pore domain channel subfamily K member 3. (299 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (454 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
TPI1Triosephosphate isomerase. (248 aa)
BCANBrevican. (1179 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (226 aa)
LOC100555140Protein-tyrosine-phosphatase. (1719 aa)
ARL3ADP ribosylation factor like GTPase 3. (182 aa)
NOVA2NOVA alternative splicing regulator 2. (480 aa)
ptprmProtein tyrosine phosphatase receptor type M. (561 aa)
VLDLRVery low density lipoprotein receptor. (874 aa)
RTN3Reticulon. (975 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (160 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (717 aa)
NPTX2Neuronal pentraxin 2. (429 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (318 aa)
MTORSerine/threonine-protein kinase TOR. (2314 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (142 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (116 aa)
EGR1Early growth response 1. (275 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (368 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CTNNA1Catenin alpha 1. (905 aa)
CCND1Cyclin D1. (154 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (456 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (223 aa)
RTN1Reticulon. (743 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (338 aa)
PCDH1Protocadherin 1. (1197 aa)
DGAT1Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (379 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1134 aa)
SYPSynaptophysin. (313 aa)
RTN4Reticulon. (975 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (363 aa)
LOC100552932CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (258 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (572 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
CLUClusterin; Belongs to the clusterin family. (467 aa)
CTNNA3Uncharacterized protein. (462 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1731 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (449 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (310 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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