STRINGSTRING
PRL PRL IRS1 IRS1 SREBF2 SREBF2 FGFR4 FGFR4 GPER1 GPER1 esr1 esr1 MAF MAF MYF6 MYF6 pou3f3 pou3f3 SMAD2 SMAD2 RPS9 RPS9 DOCK2 DOCK2 RAC2 RAC2 Rpl7a Rpl7a TRIM25 TRIM25 GATA3 GATA3 Hsd3b1 Hsd3b1 RNF144A RNF144A ITGB1 ITGB1 P4HA1 P4HA1 NEUROG1 NEUROG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRLProlactin. (229 aa)
IRS1Insulin receptor substrate 1. (1168 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1116 aa)
FGFR4Fibroblast growth factor receptor. (808 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (642 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (386 aa)
MYF6Myogenic factor. (268 aa)
pou3f3POU domain protein. (454 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
RPS9Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1831 aa)
RAC2Rac family small GTPase 2. (192 aa)
Rpl7aUncharacterized protein. (42 aa)
TRIM25Tripartite motif containing 25. (642 aa)
GATA3GATA binding protein 3. (365 aa)
Hsd3b13Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (384 aa)
RNF144ARBR-type E3 ubiquitin transferase. (320 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha 1. (542 aa)
NEUROG1Neurogenin 1. (228 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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