(92 nodes) Oocyte meiosis network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP2R5C	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (579 aa)
	YWHAQ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	CDC16	Cell division cycle 16. (625 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (828 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	YWHAG	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (219 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (397 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	SLK	STE20 like kinase. (1185 aa)
	RBX1	Ring-box 1. (108 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (299 aa)
	PPP2R5D	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (618 aa)
	FBXO5	F-box protein 5. (389 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1945 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (677 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2218 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (574 aa)
	CDC23	Cell division cycle 23. (593 aa)
	CDC25C	Cell division cycle 25C. (516 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1366 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (245 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
	ar	Androgen receptor. (232 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
	LOC100558982	Protein kinase domain-containing protein. (173 aa)
	Prkaca	Uncharacterized protein. (172 aa)
	LOC100563850	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (565 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1122 aa)
	CALML4	Calmodulin like 4. (155 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2695 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (723 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (614 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1227 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (511 aa)
	adcy5	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (794 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (313 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (628 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	camk2a	Protein kinase domain-containing protein. (504 aa)
	Cpeb2	Uncharacterized protein. (305 aa)
	PLK1	Polo like kinase 1. (416 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	RPS6KA3	Non-specific serine/threonine protein kinase. (711 aa)
	LOC100553094	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (349 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1056 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	CDC20	Cell division cycle 20. (505 aa)
	PGR	Progesterone receptor. (387 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (799 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (398 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1236 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (704 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	CDC26	Cell division cycle 26. (85 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	SMC3	Structural maintenance of chromosomes protein. (1215 aa)
	FBXW11	F-box and WD repeat domain containing 11. (444 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (456 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (563 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (408 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2659 aa)
	IGF1	Insulin like growth factor 1. (166 aa)
	rps6ka1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (468 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	CDC27	Cell division cycle 27. (834 aa)
	LOC100555994	Phosphoinositide phospholipase C. (463 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (350 aa)
	pttg1	Uncharacterized protein. (198 aa)
	rec8	Rad21_Rec8 domain-containing protein. (295 aa)
	cpeb1	Uncharacterized protein. (543 aa)
	FBXO43	F-box protein 43. (693 aa)
	PPP2R5A	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (499 aa)
	LOC100558870	Phosphoinositide phospholipase C. (631 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSACAP00000007882	ENSACAP00000009989	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY1	ADCY4	ENSACAP00000007882	ENSACAP00000009399	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY1	ADCY6	ENSACAP00000007882	ENSACAP00000008442	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.442
ADCY1	ADCY7	ENSACAP00000007882	ENSACAP00000013999	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.469
ADCY1	ADCY8	ENSACAP00000007882	ENSACAP00000010472	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.955
ADCY1	ADCY9	ENSACAP00000007882	ENSACAP00000016127	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.668
ADCY1	CALM2	ENSACAP00000007882	ENSACAP00000004388	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2; Belongs to the calmodulin family.	0.954
ADCY1	CALML4	ENSACAP00000007882	ENSACAP00000010061	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.942
ADCY1	Prkaca	ENSACAP00000007882	ENSACAP00000009669	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.923
ADCY1	adcy5	ENSACAP00000007882	ENSACAP00000010795	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.436
ADCY1	prkacb	ENSACAP00000007882	ENSACAP00000023193	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.923
ADCY2	ADCY1	ENSACAP00000009989	ENSACAP00000007882	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY2	ADCY6	ENSACAP00000009989	ENSACAP00000008442	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.582
ADCY2	ADCY8	ENSACAP00000009989	ENSACAP00000010472	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.454
ADCY2	ADCY9	ENSACAP00000009989	ENSACAP00000016127	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.574
ADCY2	Prkaca	ENSACAP00000009989	ENSACAP00000009669	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.917
ADCY2	adcy5	ENSACAP00000009989	ENSACAP00000010795	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.576
ADCY2	prkacb	ENSACAP00000009989	ENSACAP00000023193	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.917
ADCY4	ADCY1	ENSACAP00000009399	ENSACAP00000007882	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY4	ADCY6	ENSACAP00000009399	ENSACAP00000008442	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.588