STRINGSTRING
map2k2 map2k2 DAB2IP DAB2IP diablo diablo H9G4L9_ANOCA H9G4L9_ANOCA LOC100559751 LOC100559751 LOC100564288 LOC100564288 CAPN11 CAPN11 MAPK1 MAPK1 CASP10 CASP10 CFLAR CFLAR PARP4 PARP4 nfkbia nfkbia EIF2AK3 EIF2AK3 LOC100567848 LOC100567848 SPTAN1 SPTAN1 LMNB1 LMNB1 LOC100556408 LOC100556408 AKT2 AKT2 NRAS NRAS PIK3CB PIK3CB NGF NGF PDPK1 PDPK1 CAPN2 CAPN2 Fadd Fadd RELA RELA PIK3CA PIK3CA Tuba1c Tuba1c atm atm EIF2S1 EIF2S1 PARP1 PARP1 AKT3 AKT3 CASP2 CASP2 JUN JUN LOC100555021 LOC100555021 ATF4 ATF4 LOC100561730 LOC100561730 DFFB DFFB PARP2 PARP2 LOC103279556 LOC103279556 HTRA2 HTRA2 CTSS CTSS MCL1 MCL1 CTSK CTSK AIFM1 AIFM1 ctsd ctsd LOC100558982 LOC100558982 CASP7 CASP7 ITPR1 ITPR1 Pik3r2 Pik3r2 H9GGH2_ANOCA H9GGH2_ANOCA BCL2L1 BCL2L1 XIAP XIAP MAPK8 MAPK8 AKT1 AKT1 PARP3 PARP3 GADD45A GADD45A DFFA DFFA MAPK10 MAPK10 LOC100567364 LOC100567364 PTPN13 PTPN13 ITPR2 ITPR2 GADD45G GADD45G CHUK CHUK LOC100554621 LOC100554621 LOC100564389 LOC100564389 Bid Bid birc2 birc2 CASP6 CASP6 IKBKB IKBKB LOC100560655 LOC100560655 APAF1 APAF1 PIK3CD PIK3CD ctsl ctsl LOC100561542 LOC100561542 TUBA4B TUBA4B LOC100563259 LOC100563259 LOC103283025 LOC103283025 HRAS HRAS NTRK1 NTRK1 CTSB CTSB MAPK3 MAPK3 CTSC CTSC actg1 actg1 TUBA1A TUBA1A CTSH CTSH pik3r3 pik3r3 CASP9 CASP9 csf2rb csf2rb PIK3R1 PIK3R1 TNFSF10 TNFSF10 ITPR3 ITPR3 MAP3K14 MAP3K14 BAK1 BAK1 CAPN1 CAPN1 BIRC5 BIRC5 MAPK9 MAPK9 ERN1 ERN1 CTSO CTSO KRAS KRAS MAP3K5 MAP3K5 lmna lmna LOC100566904 LOC100566904 LOC100559807 LOC100559807 BAX BAX tubal3 tubal3 RIPK1 RIPK1 LOC100559158 LOC100559158 LOC100561101 LOC100561101 TRADD TRADD FASLG FASLG PIDD1 PIDD1 RAF1 RAF1 LOC100559769 LOC100559769 LOC100561388 LOC100561388 LOC100559887 LOC100559887 LOC103278072 LOC103278072
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
map2k2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
DAB2IPDAB2 interacting protein. (765 aa)
diabloUncharacterized protein. (242 aa)
H9G4L9_ANOCAPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (280 aa)
LOC100559751Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (309 aa)
LOC100564288Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (309 aa)
CAPN11Calpain 11; Belongs to the peptidase C2 family. (705 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (528 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (470 aa)
PARP4Poly [ADP-ribose] polymerase. (1783 aa)
nfkbiaANK_REP_REGION domain-containing protein. (310 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1026 aa)
LOC100567848Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (1330 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (591 aa)
LOC100556408FAT domain-containing protein. (2448 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NRASNRAS proto-oncogene, GTPase. (194 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa)
NGFNerve growth factor beta polypeptide; Belongs to the NGF-beta family. (194 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (546 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
FaddDeath domain-containing protein. (110 aa)
RELARELA proto-oncogene, NF-kB subunit. (243 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Tuba1cTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (324 aa)
atmUncharacterized protein; Belongs to the PI3/PI4-kinase family. (423 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1006 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (446 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
LOC100555021Uncharacterized protein. (567 aa)
ATF4Activating transcription factor 4. (360 aa)
LOC100561730Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (257 aa)
DFFBDNA fragmentation factor subunit beta. (340 aa)
PARP2Poly [ADP-ribose] polymerase. (566 aa)
LOC103279556Uncharacterized protein. (585 aa)
HTRA2HtrA serine peptidase 2. (362 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (333 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (329 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (289 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
ctsdPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (399 aa)
LOC100558982Protein kinase domain-containing protein. (173 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (305 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2695 aa)
Pik3r2Uncharacterized protein. (215 aa)
H9GGH2_ANOCAMATH domain-containing protein. (185 aa)
BCL2L1BCL2 like 1. (209 aa)
XIAPX-linked inhibitor of apoptosis. (568 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PARP3Poly [ADP-ribose] polymerase. (542 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (160 aa)
DFFADNA fragmentation factor subunit alpha. (320 aa)
MAPK10Mitogen-activated protein kinase. (442 aa)
LOC100567364Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1072 aa)
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2466 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (170 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (679 aa)
LOC100554621Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (483 aa)
LOC100564389Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (186 aa)
birc2Uncharacterized protein. (603 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (309 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (761 aa)
LOC100560655Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1253 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1047 aa)
ctslUncharacterized protein; Belongs to the peptidase C1 family. (372 aa)
LOC100561542Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
TUBA4BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC100563259Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (479 aa)
LOC103283025Inhibitor_I29 domain-containing protein. (125 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NTRK1Tyrosine-protein kinase receptor. (800 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (338 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (467 aa)
actg1Actin gamma 1. (374 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (285 aa)
pik3r3Uncharacterized protein. (473 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (342 aa)
csf2rbUncharacterized protein. (882 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (301 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2659 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (933 aa)
BAK1BCL2 antagonist/killer 1. (214 aa)
CAPN1Calpain 1; Belongs to the peptidase C2 family. (714 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (975 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (280 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1185 aa)
lmnaLamin A/C; Belongs to the intermediate filament family. (604 aa)
LOC100566904MATH domain-containing protein. (307 aa)
LOC100559807Uncharacterized protein. (186 aa)
BAXBCL2 associated X, apoptosis regulator. (207 aa)
tubal3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (699 aa)
LOC100559158Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
LOC100561101TNF_2 domain-containing protein. (234 aa)
TRADDTNFRSF1A associated via death domain. (327 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (261 aa)
PIDD1P53-induced death domain protein 1. (885 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (649 aa)
LOC100559769Uncharacterized protein. (340 aa)
LOC100561388Uncharacterized protein. (206 aa)
LOC100559887Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC103278072TNF_2 domain-containing protein. (239 aa)
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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