(20 nodes) Phototransduction network (Anolis carolinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDE6B	Phosphodiesterase. (856 aa)
	RGS9	Regulator of G protein signaling 9. (556 aa)
	LOC100556029	Uncharacterized protein. (120 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	GRK7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (522 aa)
	GUCY2D	Guanylate cyclase. (1102 aa)
	GUCA1B	Uncharacterized protein. (209 aa)
	guca1a	Uncharacterized protein. (198 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (611 aa)
	GUCA1C	Guanylate cyclase activator 1C. (186 aa)
	GNAT1	G protein subunit alpha transducin 1. (350 aa)
	CALML4	Calmodulin like 4. (155 aa)
	LOC100556473	Guanylate cyclase. (859 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	LOC103279985	Uncharacterized protein. (204 aa)
	rho	Rhodopsin; Photoreceptor. Light-induced isomerization of 11-cis to all- trans retinal triggers a conformational change that activates signaling via G-proteins; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (352 aa)
	grk1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (552 aa)
	PDE6G	Phosphodiesterase 6G. (87 aa)
	RCVRN	Recoverin. (200 aa)
	rh2	Blue-sensitive opsin; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. This opsin uses a vitamin A2 chromophore; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (355 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM2	CALML4	ENSACAP00000004388	ENSACAP00000010061	Calmodulin 2; Belongs to the calmodulin family.	Calmodulin like 4.	0.905
CALM2	CNGA1	ENSACAP00000004388	ENSACAP00000006477	Calmodulin 2; Belongs to the calmodulin family.	Cyclic nucleotide gated channel subunit alpha 1.	0.920
CALML4	CALM2	ENSACAP00000010061	ENSACAP00000004388	Calmodulin like 4.	Calmodulin 2; Belongs to the calmodulin family.	0.905
CALML4	CNGA1	ENSACAP00000010061	ENSACAP00000006477	Calmodulin like 4.	Cyclic nucleotide gated channel subunit alpha 1.	0.916
CNGA1	CALM2	ENSACAP00000006477	ENSACAP00000004388	Cyclic nucleotide gated channel subunit alpha 1.	Calmodulin 2; Belongs to the calmodulin family.	0.920
CNGA1	CALML4	ENSACAP00000006477	ENSACAP00000010061	Cyclic nucleotide gated channel subunit alpha 1.	Calmodulin like 4.	0.916
CNGA1	GNAT1	ENSACAP00000006477	ENSACAP00000008933	Cyclic nucleotide gated channel subunit alpha 1.	G protein subunit alpha transducin 1.	0.435
CNGA1	GNAT2	ENSACAP00000006477	ENSACAP00000011296	Cyclic nucleotide gated channel subunit alpha 1.	G protein subunit alpha transducin 2.	0.435
CNGA1	GUCA1B	ENSACAP00000006477	ENSACAP00000005867	Cyclic nucleotide gated channel subunit alpha 1.	Uncharacterized protein.	0.679
CNGA1	GUCA1C	ENSACAP00000006477	ENSACAP00000007784	Cyclic nucleotide gated channel subunit alpha 1.	Guanylate cyclase activator 1C.	0.412
CNGA1	GUCY2D	ENSACAP00000006477	ENSACAP00000005469	Cyclic nucleotide gated channel subunit alpha 1.	Guanylate cyclase.	0.554
CNGA1	LOC100556029	ENSACAP00000006477	ENSACAP00000002082	Cyclic nucleotide gated channel subunit alpha 1.	Uncharacterized protein.	0.557
CNGA1	PDE6B	ENSACAP00000006477	ENSACAP00000001148	Cyclic nucleotide gated channel subunit alpha 1.	Phosphodiesterase.	0.769
CNGA1	PDE6G	ENSACAP00000006477	ENSACAP00000014818	Cyclic nucleotide gated channel subunit alpha 1.	Phosphodiesterase 6G.	0.468
CNGA1	RCVRN	ENSACAP00000006477	ENSACAP00000015717	Cyclic nucleotide gated channel subunit alpha 1.	Recoverin.	0.653
CNGA1	RGS9	ENSACAP00000006477	ENSACAP00000001764	Cyclic nucleotide gated channel subunit alpha 1.	Regulator of G protein signaling 9.	0.470
CNGA1	grk1	ENSACAP00000006477	ENSACAP00000014232	Cyclic nucleotide gated channel subunit alpha 1.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.629
CNGA1	guca1a	ENSACAP00000006477	ENSACAP00000005885	Cyclic nucleotide gated channel subunit alpha 1.	Uncharacterized protein.	0.557
CNGA1	rh2	ENSACAP00000006477	ENSACAP00000015846	Cyclic nucleotide gated channel subunit alpha 1.	Blue-sensitive opsin; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. This opsin uses a vitamin A2 chromophore; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.	0.437
CNGA1	rho	ENSACAP00000006477	ENSACAP00000014023	Cyclic nucleotide gated channel subunit alpha 1.	Rhodopsin; Photoreceptor. Light-induced isomerization of 11-cis to all- trans retinal triggers a conformational change that activates signaling via G-proteins; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.	0.437