(56 nodes) Mixed, incl. Base-excision repair, and Non-homologous end-joining network (Capitella teleta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R7T3J4_CAPTE	Reverse transcriptase domain-containing protein. (289 aa)
	R7T4X8_CAPTE	Endo/exonuclease/phosphatase domain-containing protein. (319 aa)
	R7T4Z7_CAPTE	Poly [ADP-ribose] polymerase. (471 aa)
	R7T774_CAPTE	zf-CCHH domain-containing protein. (396 aa)
	R7T7U7_CAPTE	Uncharacterized protein. (538 aa)
	R7TBX3_CAPTE	Uncharacterized protein. (374 aa)
	R7TFE7_CAPTE	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (200 aa)
	R7TI88_CAPTE	Poly [ADP-ribose] polymerase. (994 aa)
	R7TL86_CAPTE	Uncharacterized protein. (256 aa)
	R7TLU1_CAPTE	Uncharacterized protein. (649 aa)
	R7TPP6_CAPTE	RNase H domain-containing protein. (364 aa)
	R7TPZ3_CAPTE	BRCT domain-containing protein. (400 aa)
	R7TRV9_CAPTE	Uncharacterized protein. (265 aa)
	R7TS64_CAPTE	PHD domain-containing protein. (529 aa)
	R7TVN5_CAPTE	Uncharacterized protein. (200 aa)
	R7U0C3_CAPTE	Uncharacterized protein. (604 aa)
	R7U0C7_CAPTE	Ubiquitin carboxyl-terminal hydrolase. (687 aa)
	R7U218_CAPTE	Uncharacterized protein. (165 aa)
	R7U2Y1_CAPTE	Uncharacterized protein. (247 aa)
	R7U5K1_CAPTE	ENDO3c domain-containing protein. (300 aa)
	R7U7E5_CAPTE	DNA_binding_1 domain-containing protein. (115 aa)
	R7U809_CAPTE	Uncharacterized protein. (236 aa)
	R7U8D2_CAPTE	DNA_binding_1 domain-containing protein. (147 aa)
	R7UBT8_CAPTE	ENDO3c domain-containing protein. (212 aa)
	R7UED7_CAPTE	HATPase_c domain-containing protein. (321 aa)
	R7UFL7_CAPTE	Poly [ADP-ribose] polymerase. (129 aa)
	R7UGN2_CAPTE	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (307 aa)
	R7UGR3_CAPTE	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (757 aa)
	R7UJ60_CAPTE	AP_endonuc_2 domain-containing protein. (359 aa)
	R7UJC6_CAPTE	Poly [ADP-ribose] polymerase. (2146 aa)
	R7UJL9_CAPTE	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (486 aa)
	R7UK86_CAPTE	Endo/exonuclease/phosphatase domain-containing protein. (115 aa)
	R7UKA9_CAPTE	Enkurin domain-containing protein. (339 aa)
	R7ULL3_CAPTE	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (312 aa)
	R7UMK0_CAPTE	Uncharacterized protein. (853 aa)
	R7UN65_CAPTE	Uncharacterized protein. (65 aa)
	R7UP83_CAPTE	DNA ligase. (841 aa)
	R7UQ52_CAPTE	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
	R7UR54_CAPTE	ENDO3c domain-containing protein. (231 aa)
	R7UVV7_CAPTE	DNA ligase. (905 aa)
	R7UWK5_CAPTE	UDG domain-containing protein. (224 aa)
	R7UZ60_CAPTE	Uncharacterized protein. (680 aa)
	R7V0Z7_CAPTE	Ku domain-containing protein. (553 aa)
	R7V1N6_CAPTE	DNA_binding_1 domain-containing protein. (135 aa)
	R7V1P1_CAPTE	BRCT domain-containing protein. (110 aa)
	R7V4H1_CAPTE	HHH_8 domain-containing protein. (102 aa)
	R7V789_CAPTE	Poly [ADP-ribose] polymerase. (499 aa)
	R7V819_CAPTE	Poly [ADP-ribose] polymerase. (541 aa)
	R7V8Y8_CAPTE	Ku_N domain-containing protein. (118 aa)
	R7V9V5_CAPTE	Uncharacterized protein. (234 aa)
	R7VAR0_CAPTE	FPG_CAT domain-containing protein. (268 aa)
	R7VAV7_CAPTE	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (299 aa)
	R7VD68_CAPTE	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (556 aa)
	R7VEF1_CAPTE	Uncharacterized protein. (1265 aa)
	R7VGS3_CAPTE	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (230 aa)
	R7VGT7_CAPTE	Uncharacterized protein. (197 aa)

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T3J4_CAPTE	R7T4Z7_CAPTE	R7T3J4	R7T4Z7	Reverse transcriptase domain-containing protein.	Poly [ADP-ribose] polymerase.	0.544
R7T3J4_CAPTE	R7T7U7_CAPTE	R7T3J4	R7T7U7	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.674
R7T3J4_CAPTE	R7TBX3_CAPTE	R7T3J4	R7TBX3	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.586
R7T3J4_CAPTE	R7TI88_CAPTE	R7T3J4	R7TI88	Reverse transcriptase domain-containing protein.	Poly [ADP-ribose] polymerase.	0.544
R7T3J4_CAPTE	R7TLU1_CAPTE	R7T3J4	R7TLU1	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.498
R7T3J4_CAPTE	R7TPP6_CAPTE	R7T3J4	R7TPP6	Reverse transcriptase domain-containing protein.	RNase H domain-containing protein.	0.646
R7T3J4_CAPTE	R7TPZ3_CAPTE	R7T3J4	R7TPZ3	Reverse transcriptase domain-containing protein.	BRCT domain-containing protein.	0.646
R7T3J4_CAPTE	R7TS64_CAPTE	R7T3J4	R7TS64	Reverse transcriptase domain-containing protein.	PHD domain-containing protein.	0.544
R7T3J4_CAPTE	R7U2Y1_CAPTE	R7T3J4	R7U2Y1	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.541
R7T3J4_CAPTE	R7U5K1_CAPTE	R7T3J4	R7U5K1	Reverse transcriptase domain-containing protein.	ENDO3c domain-containing protein.	0.845
R7T3J4_CAPTE	R7UBT8_CAPTE	R7T3J4	R7UBT8	Reverse transcriptase domain-containing protein.	ENDO3c domain-containing protein.	0.819
R7T3J4_CAPTE	R7UFL7_CAPTE	R7T3J4	R7UFL7	Reverse transcriptase domain-containing protein.	Poly [ADP-ribose] polymerase.	0.544
R7T3J4_CAPTE	R7UJ60_CAPTE	R7T3J4	R7UJ60	Reverse transcriptase domain-containing protein.	AP_endonuc_2 domain-containing protein.	0.949
R7T3J4_CAPTE	R7UJC6_CAPTE	R7T3J4	R7UJC6	Reverse transcriptase domain-containing protein.	Poly [ADP-ribose] polymerase.	0.544
R7T3J4_CAPTE	R7UKA9_CAPTE	R7T3J4	R7UKA9	Reverse transcriptase domain-containing protein.	Enkurin domain-containing protein.	0.646
R7T3J4_CAPTE	R7ULL3_CAPTE	R7T3J4	R7ULL3	Reverse transcriptase domain-containing protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.745
R7T3J4_CAPTE	R7UP83_CAPTE	R7T3J4	R7UP83	Reverse transcriptase domain-containing protein.	DNA ligase.	0.709
R7T3J4_CAPTE	R7UR54_CAPTE	R7T3J4	R7UR54	Reverse transcriptase domain-containing protein.	ENDO3c domain-containing protein.	0.819
R7T3J4_CAPTE	R7UVV7_CAPTE	R7T3J4	R7UVV7	Reverse transcriptase domain-containing protein.	DNA ligase.	0.674
R7T3J4_CAPTE	R7UWK5_CAPTE	R7T3J4	R7UWK5	Reverse transcriptase domain-containing protein.	UDG domain-containing protein.	0.765

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