(64 nodes) Telomere maintenance network (Capitella teleta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R7UMZ1_CAPTE	Uncharacterized protein. (132 aa)
	R7UFL7_CAPTE	Poly [ADP-ribose] polymerase. (129 aa)
	R7UEN0_CAPTE	Uncharacterized protein. (1407 aa)
	R7UE54_CAPTE	Uncharacterized protein. (140 aa)
	R7UDA2_CAPTE	Uncharacterized protein. (210 aa)
	R7UCR7_CAPTE	WD_REPEATS_REGION domain-containing protein. (385 aa)
	R7UBK7_CAPTE	Telo_bind domain-containing protein. (671 aa)
	R7UB68_CAPTE	Checkpoint protein; Belongs to the HUS1 family. (278 aa)
	R7U3A2_CAPTE	G-patch domain-containing protein. (254 aa)
	R7TZE7_CAPTE	F-box domain-containing protein. (313 aa)
	R7TZD6_CAPTE	Uncharacterized protein. (98 aa)
	R7VMB1_CAPTE	RECA_2 domain-containing protein. (146 aa)
	R7VLF7_CAPTE	Uncharacterized protein. (983 aa)
	R7VJU8_CAPTE	NFRKB_winged domain-containing protein. (780 aa)
	R7VJQ4_CAPTE	RECA_2 domain-containing protein. (138 aa)
	R7VJA8_CAPTE	Uncharacterized protein. (359 aa)
	R7VHL3_CAPTE	Uncharacterized protein. (57 aa)
	R7VGU1_CAPTE	Uncharacterized protein. (1958 aa)
	R7VG46_CAPTE	Uncharacterized protein. (67 aa)
	R7VEJ9_CAPTE	Uncharacterized protein. (853 aa)
	R7VD88_CAPTE	Telomere_reg-2 domain-containing protein. (728 aa)
	R7VCC8_CAPTE	Uncharacterized protein. (261 aa)
	R7VC05_CAPTE	Uncharacterized protein. (1262 aa)
	R7VBG2_CAPTE	Uncharacterized protein. (157 aa)
	R7VB93_CAPTE	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (179 aa)
	R7V9I5_CAPTE	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (599 aa)
	R7V8Y8_CAPTE	Ku_N domain-containing protein. (118 aa)
	R7V819_CAPTE	Poly [ADP-ribose] polymerase. (541 aa)
	R7V7P4_CAPTE	Uncharacterized protein. (71 aa)
	R7V5A4_CAPTE	AAA_23 domain-containing protein. (219 aa)
	R7TYF0_CAPTE	SMC_N domain-containing protein. (745 aa)
	R7TWQ0_CAPTE	Lactamase_B domain-containing protein. (465 aa)
	R7TVE5_CAPTE	RING-type domain-containing protein. (83 aa)
	R7TU09_CAPTE	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1501 aa)
	R7TSH5_CAPTE	FHA domain-containing protein. (318 aa)
	R7TRV9_CAPTE	Uncharacterized protein. (265 aa)
	R7TPE7_CAPTE	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (837 aa)
	R7TP90_CAPTE	Uncharacterized protein. (1211 aa)
	R7TNH9_CAPTE	Uncharacterized protein. (71 aa)
	R7TLU1_CAPTE	Uncharacterized protein. (649 aa)
	R7TH21_CAPTE	Uncharacterized protein. (260 aa)
	R7TGN2_CAPTE	FATC domain-containing protein. (49 aa)
	R7TFS6_CAPTE	FHA domain-containing protein. (484 aa)
	R7TFE7_CAPTE	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (200 aa)
	R7T7A6_CAPTE	Uncharacterized protein. (286 aa)
	R7T564_CAPTE	Myb_DNA-bind_2 domain-containing protein. (612 aa)
	R7T4Z7_CAPTE	Poly [ADP-ribose] polymerase. (471 aa)
	R7T410_CAPTE	Lactamase_B domain-containing protein. (657 aa)
	R7T3D0_CAPTE	Uncharacterized protein. (101 aa)
	R7T347_CAPTE	Helicase ATP-binding domain-containing protein. (1021 aa)
	R7V2Y0_CAPTE	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (747 aa)
	R7V2L9_CAPTE	Uncharacterized protein. (106 aa)
	R7V2A0_CAPTE	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (608 aa)
	R7V0Z7_CAPTE	Ku domain-containing protein. (553 aa)
	R7UX97_CAPTE	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3965 aa)
	R7UR47_CAPTE	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (818 aa)
	R7UQE7_CAPTE	Uncharacterized protein. (305 aa)
	R7UQ52_CAPTE	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
	R7UPJ1_CAPTE	Uncharacterized protein. (2396 aa)
	R7UL48_CAPTE	Uncharacterized protein. (98 aa)
	R7UK06_CAPTE	AAA_23 domain-containing protein. (159 aa)
	R7UIT5_CAPTE	Mre11_DNA_bind domain-containing protein. (543 aa)
	R7UGK4_CAPTE	Uncharacterized protein. (98 aa)
	R7UFU2_CAPTE	ATP-dependent DNA helicase; Belongs to the helicase family. (92 aa)

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T347_CAPTE	R7T4Z7_CAPTE	R7T347	R7T4Z7	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7T564_CAPTE	R7T347	R7T564	Helicase ATP-binding domain-containing protein.	Myb_DNA-bind_2 domain-containing protein.	0.589
R7T347_CAPTE	R7TLU1_CAPTE	R7T347	R7TLU1	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.658
R7T347_CAPTE	R7TSH5_CAPTE	R7T347	R7TSH5	Helicase ATP-binding domain-containing protein.	FHA domain-containing protein.	0.924
R7T347_CAPTE	R7TU09_CAPTE	R7T347	R7TU09	Helicase ATP-binding domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.739
R7T347_CAPTE	R7UB68_CAPTE	R7T347	R7UB68	Helicase ATP-binding domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.619
R7T347_CAPTE	R7UBK7_CAPTE	R7T347	R7UBK7	Helicase ATP-binding domain-containing protein.	Telo_bind domain-containing protein.	0.637
R7T347_CAPTE	R7UCR7_CAPTE	R7T347	R7UCR7	Helicase ATP-binding domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.700
R7T347_CAPTE	R7UE54_CAPTE	R7T347	R7UE54	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.426
R7T347_CAPTE	R7UEN0_CAPTE	R7T347	R7UEN0	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.426
R7T347_CAPTE	R7UFL7_CAPTE	R7T347	R7UFL7	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7UFU2_CAPTE	R7T347	R7UFU2	Helicase ATP-binding domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family.	0.744
R7T347_CAPTE	R7UIT5_CAPTE	R7T347	R7UIT5	Helicase ATP-binding domain-containing protein.	Mre11_DNA_bind domain-containing protein.	0.879
R7T347_CAPTE	R7UPJ1_CAPTE	R7T347	R7UPJ1	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.676
R7T347_CAPTE	R7UR47_CAPTE	R7T347	R7UR47	Helicase ATP-binding domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.830
R7T347_CAPTE	R7V2A0_CAPTE	R7T347	R7V2A0	Helicase ATP-binding domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.732
R7T347_CAPTE	R7V2Y0_CAPTE	R7T347	R7V2Y0	Helicase ATP-binding domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.682
R7T347_CAPTE	R7V5A4_CAPTE	R7T347	R7V5A4	Helicase ATP-binding domain-containing protein.	AAA_23 domain-containing protein.	0.649
R7T347_CAPTE	R7V819_CAPTE	R7T347	R7V819	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7V9I5_CAPTE	R7T347	R7V9I5	Helicase ATP-binding domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.879

page 1 of 62

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About