(52 nodes) Regulation of double-strand break repair network (Capitella teleta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R7U4A7_CAPTE	DUF4502 domain-containing protein. (505 aa)
	R7UE45_CAPTE	Uncharacterized protein. (59 aa)
	R7UEP4_CAPTE	ANK_REP_REGION domain-containing protein. (137 aa)
	R7UFJ4_CAPTE	Uncharacterized protein. (59 aa)
	R7UFL7_CAPTE	Poly [ADP-ribose] polymerase. (129 aa)
	R7UG42_CAPTE	Deacetylase sirtuin-type domain-containing protein. (925 aa)
	R7UI37_CAPTE	Uncharacterized protein. (777 aa)
	R7UIH0_CAPTE	Uncharacterized protein. (930 aa)
	R7UJL8_CAPTE	Uncharacterized protein. (421 aa)
	R7URF6_CAPTE	Uncharacterized protein. (238 aa)
	R7UT90_CAPTE	Uncharacterized protein. (677 aa)
	R7UX97_CAPTE	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3965 aa)
	R7V282_CAPTE	SMC hinge domain-containing protein. (1868 aa)
	R7V2Q8_CAPTE	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (622 aa)
	R7V3C5_CAPTE	Fork-head domain-containing protein. (108 aa)
	R7T347_CAPTE	Helicase ATP-binding domain-containing protein. (1021 aa)
	R7T3J9_CAPTE	Uncharacterized protein. (62 aa)
	R7T4Z7_CAPTE	Poly [ADP-ribose] polymerase. (471 aa)
	R7T564_CAPTE	Myb_DNA-bind_2 domain-containing protein. (612 aa)
	R7TBT3_CAPTE	C2H2-type domain-containing protein. (616 aa)
	R7TDP5_CAPTE	Uncharacterized protein. (836 aa)
	R7TFE7_CAPTE	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (200 aa)
	R7TG72_CAPTE	Uncharacterized protein. (2617 aa)
	R7TGN2_CAPTE	FATC domain-containing protein. (49 aa)
	R7TIX1_CAPTE	DUF3715 domain-containing protein. (915 aa)
	R7TJH5_CAPTE	Enhancer of polycomb-like protein. (223 aa)
	R7TPE7_CAPTE	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (837 aa)
	R7TPW9_CAPTE	Uncharacterized protein. (91 aa)
	R7TRD6_CAPTE	Uncharacterized protein. (1019 aa)
	R7TRI0_CAPTE	Uncharacterized protein. (108 aa)
	R7TVE5_CAPTE	RING-type domain-containing protein. (83 aa)
	R7U372_CAPTE	Bromo domain-containing protein. (847 aa)
	R7U5K1_CAPTE	ENDO3c domain-containing protein. (300 aa)
	R7V5N9_CAPTE	DUF3715 domain-containing protein. (556 aa)
	R7UBK7_CAPTE	Telo_bind domain-containing protein. (671 aa)
	R7UBY1_CAPTE	YL1_C domain-containing protein. (378 aa)
	R7UCR7_CAPTE	WD_REPEATS_REGION domain-containing protein. (385 aa)
	R7V6Y5_CAPTE	UvrD-like helicase C-terminal domain-containing protein. (405 aa)
	R7V756_CAPTE	RAD51_interact domain-containing protein. (384 aa)
	R7V7U7_CAPTE	Uncharacterized protein. (290 aa)
	R7V7W0_CAPTE	DEK_C domain-containing protein. (214 aa)
	R7V819_CAPTE	Poly [ADP-ribose] polymerase. (541 aa)
	R7V8E5_CAPTE	Uncharacterized protein. (822 aa)
	R7V9M0_CAPTE	ARID domain-containing protein. (72 aa)
	R7VFV5_CAPTE	F-box domain-containing protein. (764 aa)
	R7VG07_CAPTE	Uncharacterized protein. (1640 aa)
	R7VG19_CAPTE	SAP domain-containing protein. (184 aa)
	R7VIK2_CAPTE	Uncharacterized protein. (73 aa)
	R7VJQ4_CAPTE	RECA_2 domain-containing protein. (138 aa)
	R7VLD9_CAPTE	Uncharacterized protein. (115 aa)
	R7VM94_CAPTE	Uncharacterized protein. (654 aa)
	R7VMB1_CAPTE	RECA_2 domain-containing protein. (146 aa)

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T347_CAPTE	R7T4Z7_CAPTE	R7T347	R7T4Z7	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7T564_CAPTE	R7T347	R7T564	Helicase ATP-binding domain-containing protein.	Myb_DNA-bind_2 domain-containing protein.	0.589
R7T347_CAPTE	R7TRD6_CAPTE	R7T347	R7TRD6	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.839
R7T347_CAPTE	R7UBK7_CAPTE	R7T347	R7UBK7	Helicase ATP-binding domain-containing protein.	Telo_bind domain-containing protein.	0.637
R7T347_CAPTE	R7UCR7_CAPTE	R7T347	R7UCR7	Helicase ATP-binding domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.700
R7T347_CAPTE	R7UEP4_CAPTE	R7T347	R7UEP4	Helicase ATP-binding domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.917
R7T347_CAPTE	R7UFL7_CAPTE	R7T347	R7UFL7	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7UI37_CAPTE	R7T347	R7UI37	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.439
R7T347_CAPTE	R7UJL8_CAPTE	R7T347	R7UJL8	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.439
R7T347_CAPTE	R7V2Q8_CAPTE	R7T347	R7V2Q8	Helicase ATP-binding domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.606
R7T347_CAPTE	R7V6Y5_CAPTE	R7T347	R7V6Y5	Helicase ATP-binding domain-containing protein.	UvrD-like helicase C-terminal domain-containing protein.	0.436
R7T347_CAPTE	R7V756_CAPTE	R7T347	R7V756	Helicase ATP-binding domain-containing protein.	RAD51_interact domain-containing protein.	0.601
R7T347_CAPTE	R7V819_CAPTE	R7T347	R7V819	Helicase ATP-binding domain-containing protein.	Poly [ADP-ribose] polymerase.	0.553
R7T347_CAPTE	R7VFV5_CAPTE	R7T347	R7VFV5	Helicase ATP-binding domain-containing protein.	F-box domain-containing protein.	0.436
R7T347_CAPTE	R7VJQ4_CAPTE	R7T347	R7VJQ4	Helicase ATP-binding domain-containing protein.	RECA_2 domain-containing protein.	0.727
R7T347_CAPTE	R7VMB1_CAPTE	R7T347	R7VMB1	Helicase ATP-binding domain-containing protein.	RECA_2 domain-containing protein.	0.727
R7T4Z7_CAPTE	R7T347_CAPTE	R7T4Z7	R7T347	Poly [ADP-ribose] polymerase.	Helicase ATP-binding domain-containing protein.	0.553
R7T4Z7_CAPTE	R7TFE7_CAPTE	R7T4Z7	R7TFE7	Poly [ADP-ribose] polymerase.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.408
R7T4Z7_CAPTE	R7TGN2_CAPTE	R7T4Z7	R7TGN2	Poly [ADP-ribose] polymerase.	FATC domain-containing protein.	0.408
R7T4Z7_CAPTE	R7TPE7_CAPTE	R7T4Z7	R7TPE7	Poly [ADP-ribose] polymerase.	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.	0.553

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