(42 nodes) Recognition of DNA damage by PCNA-containing replication complex network (Capitella teleta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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Your Input:
	R7U4I2_CAPTE	WD_REPEATS_REGION domain-containing protein. (708 aa)
	R7T5N4_CAPTE	REPA_OB_2 domain-containing protein. (418 aa)
	R7TA07_CAPTE	Uncharacterized protein. (679 aa)
	R7TGI4_CAPTE	DNA polymerase. (1052 aa)
	R7TJR2_CAPTE	Uncharacterized protein. (457 aa)
	R7TKF0_CAPTE	CULLIN_2 domain-containing protein; Belongs to the cullin family. (133 aa)
	R7TLY6_CAPTE	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	R7TQV3_CAPTE	Ubiquitin-like domain-containing protein. (51 aa)
	R7TRS2_CAPTE	Uncharacterized protein. (469 aa)
	R7TUP1_CAPTE	Uncharacterized protein. (1483 aa)
	R7TVC4_CAPTE	Uncharacterized protein. (180 aa)
	R7TVV9_CAPTE	CBFD_NFYB_HMF domain-containing protein. (150 aa)
	R7TYJ8_CAPTE	Ubiquitin-like domain-containing protein. (93 aa)
	R7U1V4_CAPTE	Uncharacterized protein. (367 aa)
	R7U3M5_CAPTE	BTB domain-containing protein. (453 aa)
	R7U5X9_CAPTE	AAA domain-containing protein. (358 aa)
	R7U9D6_CAPTE	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	R7UDK8_CAPTE	USP domain-containing protein. (476 aa)
	R7UDQ3_CAPTE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (706 aa)
	R7UIH1_CAPTE	CPSF_A domain-containing protein. (1084 aa)
	R7ULZ2_CAPTE	AAA domain-containing protein. (333 aa)
	R7UNY3_CAPTE	CBFD_NFYB_HMF domain-containing protein. (112 aa)
	R7UQ01_CAPTE	AAA domain-containing protein. (214 aa)
	R7UQU5_CAPTE	KxDL domain-containing protein. (151 aa)
	R7US71_CAPTE	Uncharacterized protein. (231 aa)
	R7UW60_CAPTE	WD_REPEATS_REGION domain-containing protein. (689 aa)
	R7UWH7_CAPTE	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
	R7UY52_CAPTE	RING-type domain-containing protein. (108 aa)
	R7UY95_CAPTE	Ubiquitin-like domain-containing protein. (50 aa)
	R7UZN3_CAPTE	AAA domain-containing protein. (343 aa)
	R7V2A0_CAPTE	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (608 aa)
	R7V2K8_CAPTE	Uncharacterized protein. (229 aa)
	R7V3G1_CAPTE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2273 aa)
	R7V700_CAPTE	Ubiquitin-like domain-containing protein. (99 aa)
	R7V9M6_CAPTE	Uncharacterized protein. (124 aa)
	R7VA93_CAPTE	Uncharacterized protein. (112 aa)
	R7VAJ1_CAPTE	Uncharacterized protein. (188 aa)
	R7VAU2_CAPTE	BRCT domain-containing protein. (730 aa)
	R7VEN2_CAPTE	Uncharacterized protein. (409 aa)
	R7VFZ8_CAPTE	AAA domain-containing protein. (1709 aa)
	R7VH85_CAPTE	Ubiquitin-like domain-containing protein. (93 aa)
	R7VKU2_CAPTE	AAA domain-containing protein. (340 aa)

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T5N4_CAPTE	R7TA07_CAPTE	R7T5N4	R7TA07	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.800
R7T5N4_CAPTE	R7TGI4_CAPTE	R7T5N4	R7TGI4	REPA_OB_2 domain-containing protein.	DNA polymerase.	0.810
R7T5N4_CAPTE	R7TJR2_CAPTE	R7T5N4	R7TJR2	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.491
R7T5N4_CAPTE	R7TQV3_CAPTE	R7T5N4	R7TQV3	REPA_OB_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.491
R7T5N4_CAPTE	R7TRS2_CAPTE	R7T5N4	R7TRS2	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.729
R7T5N4_CAPTE	R7TVC4_CAPTE	R7T5N4	R7TVC4	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.491
R7T5N4_CAPTE	R7TVV9_CAPTE	R7T5N4	R7TVV9	REPA_OB_2 domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.679
R7T5N4_CAPTE	R7TYJ8_CAPTE	R7T5N4	R7TYJ8	REPA_OB_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.491
R7T5N4_CAPTE	R7U1V4_CAPTE	R7T5N4	R7U1V4	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.585
R7T5N4_CAPTE	R7U4I2_CAPTE	R7T5N4	R7U4I2	REPA_OB_2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.635
R7T5N4_CAPTE	R7U5X9_CAPTE	R7T5N4	R7U5X9	REPA_OB_2 domain-containing protein.	AAA domain-containing protein.	0.867
R7T5N4_CAPTE	R7U9D6_CAPTE	R7T5N4	R7U9D6	REPA_OB_2 domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.955
R7T5N4_CAPTE	R7UDQ3_CAPTE	R7T5N4	R7UDQ3	REPA_OB_2 domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.790
R7T5N4_CAPTE	R7UIH1_CAPTE	R7T5N4	R7UIH1	REPA_OB_2 domain-containing protein.	CPSF_A domain-containing protein.	0.658
R7T5N4_CAPTE	R7ULZ2_CAPTE	R7T5N4	R7ULZ2	REPA_OB_2 domain-containing protein.	AAA domain-containing protein.	0.860
R7T5N4_CAPTE	R7UQ01_CAPTE	R7T5N4	R7UQ01	REPA_OB_2 domain-containing protein.	AAA domain-containing protein.	0.855
R7T5N4_CAPTE	R7US71_CAPTE	R7T5N4	R7US71	REPA_OB_2 domain-containing protein.	Uncharacterized protein.	0.491
R7T5N4_CAPTE	R7UW60_CAPTE	R7T5N4	R7UW60	REPA_OB_2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.585
R7T5N4_CAPTE	R7UWH7_CAPTE	R7T5N4	R7UWH7	REPA_OB_2 domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.789
R7T5N4_CAPTE	R7UY95_CAPTE	R7T5N4	R7UY95	REPA_OB_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.491

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