node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | R7TPP6_CAPTE | R7V1L7 | R7TPP6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RNase H domain-containing protein. | 0.758 |
FEN1 | R7TPZ3_CAPTE | R7V1L7 | R7TPZ3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | BRCT domain-containing protein. | 0.758 |
FEN1 | R7TRV9_CAPTE | R7V1L7 | R7TRV9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.452 |
FEN1 | R7UIT5_CAPTE | R7V1L7 | R7UIT5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Mre11_DNA_bind domain-containing protein. | 0.980 |
FEN1 | R7UKA9_CAPTE | R7V1L7 | R7UKA9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Enkurin domain-containing protein. | 0.758 |
FEN1 | R7UQ52_CAPTE | R7V1L7 | R7UQ52 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. | 0.691 |
FEN1 | R7UVV7_CAPTE | R7V1L7 | R7UVV7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.852 |
FEN1 | R7V0Z7_CAPTE | R7V1L7 | R7V0Z7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ku domain-containing protein. | 0.680 |
FEN1 | R7V5A4_CAPTE | R7V1L7 | R7V5A4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AAA_23 domain-containing protein. | 0.936 |
FEN1 | R7V8Y8_CAPTE | R7V1L7 | R7V8Y8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ku_N domain-containing protein. | 0.680 |
FEN1 | R7V9I5_CAPTE | R7V1L7 | R7V9I5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.980 |
FEN1 | R7VBG2_CAPTE | R7V1L7 | R7VBG2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.936 |
R7TFE7_CAPTE | R7TGN2_CAPTE | R7TFE7 | R7TGN2 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | FATC domain-containing protein. | 0.438 |
R7TFE7_CAPTE | R7TL86_CAPTE | R7TFE7 | R7TL86 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.730 |
R7TFE7_CAPTE | R7TPP6_CAPTE | R7TFE7 | R7TPP6 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | RNase H domain-containing protein. | 0.613 |
R7TFE7_CAPTE | R7TPZ3_CAPTE | R7TFE7 | R7TPZ3 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | BRCT domain-containing protein. | 0.613 |
R7TFE7_CAPTE | R7TRV9_CAPTE | R7TFE7 | R7TRV9 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.974 |
R7TFE7_CAPTE | R7UIT5_CAPTE | R7TFE7 | R7UIT5 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | Mre11_DNA_bind domain-containing protein. | 0.694 |
R7TFE7_CAPTE | R7UQ52_CAPTE | R7TFE7 | R7UQ52 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. | 0.978 |
R7TFE7_CAPTE | R7UVV7_CAPTE | R7TFE7 | R7UVV7 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. | DNA ligase. | 0.935 |