(39 nodes) Notch signaling pathway network (Capitella teleta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R7TYM7_CAPTE	Ncstrn_small domain-containing protein. (685 aa)
	R7TDD0_CAPTE	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (543 aa)
	R7TE15_CAPTE	Uncharacterized protein. (413 aa)
	R7TE48_CAPTE	Uncharacterized protein. (1826 aa)
	R7TEK1_CAPTE	Hairy protein. (114 aa)
	R7TLW0_CAPTE	Uncharacterized protein. (793 aa)
	R7TSJ5_CAPTE	N-acetyltransferase domain-containing protein. (109 aa)
	R7TW63_CAPTE	Uncharacterized protein. (456 aa)
	R7TY88_CAPTE	SKIP_SNW domain-containing protein. (464 aa)
	R7U162_CAPTE	AXH domain-containing protein. (171 aa)
	R7U573_CAPTE	Uncharacterized protein. (207 aa)
	R7U585_CAPTE	Ncstrn_small domain-containing protein. (730 aa)
	R7U8V5_CAPTE	BHLH domain-containing protein. (496 aa)
	R7UB93_CAPTE	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (389 aa)
	R7UEH4_CAPTE	Uncharacterized protein. (101 aa)
	R7UGL5_CAPTE	Cir_N domain-containing protein. (303 aa)
	R7UKW9_CAPTE	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (431 aa)
	R7UM85_CAPTE	Uncharacterized protein. (620 aa)
	R7US05_CAPTE	Uncharacterized protein. (273 aa)
	R7USG1_CAPTE	Uncharacterized protein. (671 aa)
	R7USZ4_CAPTE	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (424 aa)
	R7UUL5_CAPTE	Uncharacterized protein. (773 aa)
	R7UWD3_CAPTE	PID domain-containing protein. (390 aa)
	R7UWR6_CAPTE	Uncharacterized protein. (105 aa)
	R7UWS1_CAPTE	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (468 aa)
	R7UWW0_CAPTE	Uncharacterized protein. (346 aa)
	R7UY18_CAPTE	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (412 aa)
	R7UY62_CAPTE	HES3. (218 aa)
	R7UZ33_CAPTE	Uncharacterized protein. (197 aa)
	R7UZI1_CAPTE	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (412 aa)
	R7UZW6_CAPTE	HESR2. (300 aa)
	R7V1F1_CAPTE	EGF_CA domain-containing protein. (78 aa)
	R7V1S0_CAPTE	Bromo domain-containing protein. (126 aa)
	R7V4B2_CAPTE	Uncharacterized protein. (614 aa)
	R7V4W4_CAPTE	HES2. (198 aa)
	R7V4Z9_CAPTE	Uncharacterized protein. (2250 aa)
	R7V606_CAPTE	Uncharacterized protein. (589 aa)
	R7V908_CAPTE	Uncharacterized protein. (249 aa)
	R7VL64_CAPTE	Uncharacterized protein. (609 aa)

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7TDD0_CAPTE	R7TLW0_CAPTE	R7TDD0	R7TLW0	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.907
R7TDD0_CAPTE	R7TSJ5_CAPTE	R7TDD0	R7TSJ5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	N-acetyltransferase domain-containing protein.	0.648
R7TDD0_CAPTE	R7TW63_CAPTE	R7TDD0	R7TW63	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.854
R7TDD0_CAPTE	R7TY88_CAPTE	R7TDD0	R7TY88	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	SKIP_SNW domain-containing protein.	0.694
R7TDD0_CAPTE	R7UGL5_CAPTE	R7TDD0	R7UGL5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Cir_N domain-containing protein.	0.783
R7TDD0_CAPTE	R7USZ4_CAPTE	R7TDD0	R7USZ4	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.891
R7TDD0_CAPTE	R7UUL5_CAPTE	R7TDD0	R7UUL5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.648
R7TDD0_CAPTE	R7V1S0_CAPTE	R7TDD0	R7V1S0	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Bromo domain-containing protein.	0.648
R7TDD0_CAPTE	R7V4Z9_CAPTE	R7TDD0	R7V4Z9	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.883
R7TE15_CAPTE	R7TE48_CAPTE	R7TE15	R7TE48	Uncharacterized protein.	Uncharacterized protein.	0.952
R7TE15_CAPTE	R7V4Z9_CAPTE	R7TE15	R7V4Z9	Uncharacterized protein.	Uncharacterized protein.	0.691
R7TE48_CAPTE	R7TE15_CAPTE	R7TE48	R7TE15	Uncharacterized protein.	Uncharacterized protein.	0.952
R7TE48_CAPTE	R7V4Z9_CAPTE	R7TE48	R7V4Z9	Uncharacterized protein.	Uncharacterized protein.	0.691
R7TEK1_CAPTE	R7TLW0_CAPTE	R7TEK1	R7TLW0	Hairy protein.	Uncharacterized protein.	0.773
R7TEK1_CAPTE	R7TW63_CAPTE	R7TEK1	R7TW63	Hairy protein.	Uncharacterized protein.	0.737
R7TLW0_CAPTE	R7TDD0_CAPTE	R7TLW0	R7TDD0	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.907
R7TLW0_CAPTE	R7TEK1_CAPTE	R7TLW0	R7TEK1	Uncharacterized protein.	Hairy protein.	0.773
R7TLW0_CAPTE	R7TW63_CAPTE	R7TLW0	R7TW63	Uncharacterized protein.	Uncharacterized protein.	0.878
R7TLW0_CAPTE	R7TYM7_CAPTE	R7TLW0	R7TYM7	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.424
R7TLW0_CAPTE	R7U585_CAPTE	R7TLW0	R7U585	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.424

page 1 of 12

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About