STRINGSTRING
yihI yihI IL0030 IL0030 IL0223 IL0223 IL0249 IL0249 IL0351 IL0351 mshI_1 mshI_1 mshI_2 mshI_2 mshJ mshJ mshK mshK mshL mshL mshM mshM mshN mshN mshE mshE mshG mshG IL0372 IL0372 mshB mshB mshA mshA mshC mshC mshD mshD mshO mshO mshP mshP mshQ mshQ IL0380 IL0380 mreB mreB mreC mreC mreD mreD maf_1 maf_1 cafA cafA IL0386 IL0386 IL0387 IL0387 tldD tldD yacG yacG zapD zapD coaE coaE pulO pulO pulF pulF pulE pulE pppD pppD ampD ampD ampE ampE pdhR pdhR aceE aceE aceF aceF pepO pepO IL0462 IL0462 IL0479 IL0479 ordL ordL IL0484 IL0484 ahcY ahcY gsk gsk cbiB cbiB IL0488 IL0488 IL0490 IL0490 IL0501 IL0501 mutH mutH IL0624 IL0624 IL0677 IL0677 IL0678 IL0678 IL0688 IL0688 IL0712 IL0712 IL0715 IL0715 IL0717 IL0717 IL0771 IL0771 IL0849 IL0849 IL0850 IL0850 IL0851 IL0851 IL0852 IL0852 IL0853 IL0853 syd syd IL0856 IL0856 IL0857 IL0857 IL0859 IL0859 IL0860 IL0860 IL0916 IL0916 IL0962 IL0962 IL0963 IL0963 astB astB IL1023 IL1023 IL1072 IL1072 IL1076 IL1076 IL1153 IL1153 IL1154 IL1154 IL1169 IL1169 IL1170 IL1170 IL1258 IL1258 IL1259 IL1259 IL1260 IL1260 IL1261 IL1261 IL1262 IL1262 IL1265 IL1265 zapC zapC rlmL rlmL IL1283 IL1283 IL1284 IL1284 IL1285 IL1285 rmf rmf IL1401 IL1401 IL1403 IL1403 IL1452 IL1452 IL1465 IL1465 wrbA wrbA IL1467 IL1467 seqA seqA IL1474 IL1474 IL1519 IL1519 IL1521 IL1521 IL1538 IL1538 astE astE IL1692 IL1692 cysB cysB IL1711 IL1711 sUI1 sUI1 motY motY fadR_2 fadR_2 dsbB dsbB priC priC IL1861 IL1861 IL1862 IL1862 IL1875 IL1875 IL1962 IL1962 IL1963 IL1963 exeB exeB exeA exeA cca cca motX motX IL2015 IL2015 pulN pulN pulM pulM pulL pulL pulK pulK pulJ pulJ IL2021 IL2021 pulH pulH pulG pulG pulF-2 pulF-2 pulE-2 pulE-2 pulD pulD pulC pulC IL2028 IL2028 hslO hslO IL2102 IL2102 IL2132 IL2132 IL2225 IL2225 IL2274 IL2274 IL2278 IL2278 IL2279 IL2279 IL2294 IL2294 IL2295 IL2295 comJ comJ IL2314 IL2314 IL2315 IL2315 astD astD IL2317 IL2317 IL2319 IL2319 IL2320 IL2320 IL2345 IL2345 IL2428 IL2428 IL2439 IL2439 IL2440 IL2440 acrR acrR metJ metJ dsbA dsbA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yihIUncharacterized conserved protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (137 aa)
IL0030Uncharacterized conserved secreted protein. (152 aa)
IL0223Uncharacterized conserved protein. (202 aa)
IL0249Uncharacterized conserved secreted protein; Contains internal repeats. (461 aa)
IL0351Uncharacterized periplasmic binding protein. (263 aa)
mshI_1Type II secretory pathway component. (303 aa)
mshI_2Type II secretory pathway component. (202 aa)
mshJType II secretory pathway component. (211 aa)
mshKType II secretory pathway component. (113 aa)
mshLType II secretory pathway; PulD-like. (557 aa)
mshMGeneral secretion pathway protein, ATPase. (302 aa)
mshNMembrane associated TPR repeats containing protein. (357 aa)
mshEType II secretory pathway, ATPase; MshE-like. (571 aa)
mshGType II secretory pathway; PulF-like. (412 aa)
IL0372Predicted Type II secretory pathway component. (149 aa)
mshBPilin protein. (201 aa)
mshAType II secretory pathway, pseudopilin; PulG-like. (170 aa)
mshCType II secretory pathway component; PilE-like protein. (144 aa)
mshDPilin protein. (173 aa)
mshOTfp-like pilus assembly protein; PilW-like protein. (272 aa)
mshPType II secretory pathway component. (143 aa)
mshQType II secretory pathway component; Component PulK. (1431 aa)
IL0380Secreted protein with uncharacterized domain; Possibly involved in signal transduction. (619 aa)
mreBActin-like ATPase; Involved in cell morphogenesis. (347 aa)
mreCRod shape-determining protein; Involved in formation and maintenance of cell shape. (285 aa)
mreDRod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (161 aa)
maf_1Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (198 aa)
cafARNase G. (489 aa)
IL0386Uncharacterized conserved membrane protein. (1289 aa)
IL0387Predicted amidohydrolase, nitrilase family. (265 aa)
tldDPredicted Zn-dependent protease; TldD. (473 aa)
yacGUncharacterized zinc finger protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (64 aa)
zapDUncharacterized conserved membrane protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (254 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)
pulOType II pili prepilin peptidase PilD/XcpA; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (286 aa)
pulFType II secretory pathway, PulF-like. (392 aa)
pulEType II secretory pathway, ATPase PulE. (437 aa)
pppDPilin protein PilA. (160 aa)
ampDN-acetyl-anhydromuramyl-L-alanine amidase. (168 aa)
ampEMembrane protein required for beta-lactamase induction. (274 aa)
pdhRProbable transcriptional regulator for pyruvate dehydrogenase complex. (227 aa)
aceEPyruvate dehydrogenase (decarboxylase component, E1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
aceFPyruvate dehydrogenase (dihydrolipoyltransacetylase component, E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (591 aa)
pepOSecreted zinc metalloproteinase. (689 aa)
IL0462Hypothetical protein. (91 aa)
IL0479Uncharacterized conserved secreted protein. (124 aa)
ordLD-amino acid oxidase family protein (deaminating). (439 aa)
IL0484Acetyltransferase, GNAT family. (189 aa)
ahcYS-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (459 aa)
gskSugar kinase, ribokinase family. (336 aa)
cbiBCobalamin biosynthesis membrane protein. (318 aa)
IL0488Uncharacterized conserved secreted protein. (183 aa)
IL0490HPt domain. (116 aa)
IL0501Uncharacterized conserved membrane protein. (220 aa)
mutHDNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (224 aa)
IL0624Uncharacterized conserved protein. (216 aa)
IL0677Nucleoid-associated protein. (347 aa)
IL0678Membrane-associated hydrolase of alkaline phosphatase superfamily. (544 aa)
IL0688Uncharacterized periplasmic substrate-binding protein. (280 aa)
IL0712Uncharacterized conserved secreted protein. (100 aa)
IL0715Uncharacterized conserved secreted protein. (146 aa)
IL0717Predicted membrane serine peptidase, rhomboid homolog. (189 aa)
IL0771Uncharacterized conserved protein. (225 aa)
IL0849Predicted pseudouridylate synthase, Rlu family. (236 aa)
IL0850Uncharacterized conserved protein. (114 aa)
IL0851Uncharacterized conserved protein. (343 aa)
IL0852Uncharacterized conserved secreted protein. (103 aa)
IL0853Predicted acetyltransferase, GNAT family. (226 aa)
sydSyd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (183 aa)
IL0856Aminopeptidase N family protein, contains PDZ domain. (601 aa)
IL0857Signaling protein with a sensor domain and GGDEF domain. (507 aa)
IL0859SmpA /OmlA family lipoprotein. (128 aa)
IL0860Hypothetical protein. (507 aa)
IL0916Carboxyl-terminal protease. (447 aa)
IL0962Predicted extracellular metal-dependent peptidase. (385 aa)
IL0963NlpI-like lipoprotein; May be involved in cell division. (294 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (449 aa)
IL1023Uncharacterized conserved protein. (98 aa)
IL1072Predicted glycosyltransferase. (637 aa)
IL1076IS4-like transposase. (441 aa)
IL1153Uncharacterized conserved secreted protein. (159 aa)
IL1154Uncharacterized conserved secreted protein. (387 aa)
IL1169Uncharacterized conserved secreted protein. (199 aa)
IL1170Uncharacterized conserved secreted protein. (188 aa)
IL1258Aminopeptidase N family protein, contains PDZ domain. (589 aa)
IL1259Predicted glycosyltransferase. (229 aa)
IL1260Signal transduction ATPase, FimS family. (364 aa)
IL1261Response regulator of the LytR/AlgR family. (272 aa)
IL1262Uncharacterized conserved secreted protein. (281 aa)
IL1265Uncharacterized conserved protein. (251 aa)
zapCUncharacterized conserved protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (184 aa)
rlmLN6-adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (704 aa)
IL1283Thioredoxin related protein. (79 aa)
IL1284ATPase component of ABC transporters with duplicated ATPase domains. (648 aa)
IL1285Uncharacterized conserved secreted or membrane protein. (581 aa)
rmfRibosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family. (58 aa)
IL1401Zn-ribbon protein. (69 aa)
IL1403Uncharacterized conserved secreted protein. (344 aa)
IL1452Uncharacterized conserved protein. (144 aa)
IL1465Glutaredoxin family protein. (115 aa)
wrbAMultimeric flavodoxin WrbA. (185 aa)
IL1467Uncharacterized conserved membrane protein. (129 aa)
seqANegative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. (160 aa)
IL1474Uncharacterized conserved membrane protein. (71 aa)
IL1519Uncharacterized conserved protein. (209 aa)
IL1521Uncharacterized conserved secreted protein. (365 aa)
IL15382OG-Fe(II) oxygenase family enzyme. (231 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (343 aa)
IL1692Uncharacterized conserved protein. (406 aa)
cysBProbable positive transcriptional regulator for cysteine regulon; Belongs to the LysR transcriptional regulatory family. (324 aa)
IL1711Uncharacterized conserved secreted or membrane protein. (252 aa)
sUI1Possible translation initiation factor, Sui1 family. (111 aa)
motYSodium-type flagellar protein motY precursor; Polar flagellum motor protein. (298 aa)
fadR_2Negative regulator for fad regulon; Multifunctional regulator of fatty acid metabolism. (236 aa)
dsbBDisulfide bond formation protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (181 aa)
priCPrimosomal replication protein C. (176 aa)
IL1861Histone deacetylase/AcuC/AphA family protein. (311 aa)
IL1862Uncharacterized conserved protein. (91 aa)
IL1875Uncharacterized conserved protein. (834 aa)
IL1962Predicted membrane protein. (145 aa)
IL1963Acyl-CoA dehydrogenase family protein. (594 aa)
exeBGeneral secretion pathway protein B. (236 aa)
exeAGeneral secretion pathway protein, ATPase. (472 aa)
ccatRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. (370 aa)
motXNa+-type flagellar protein, contains TPR repeats. (208 aa)
IL2015Small-conductance mechanosensitive channel. (272 aa)
pulNType II secretory pathway, component PulN. (248 aa)
pulMType II secretory pathway, component PulM; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (172 aa)
pulLType II secretory pathway, component PulL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (406 aa)
pulKType II secretory pathway, component PulK. (328 aa)
pulJType II secretory pathway, component PulJ. (227 aa)
IL2021Type II secretory pathway, pseudopilin PulG-like. (130 aa)
pulHType II secretory pathway, component PulH. (183 aa)
pulGType II secretory pathway, pseudopilin PulG. (145 aa)
pulF-2Type II secretory pathway, component PulF. (408 aa)
pulE-2Type II secretory pathway, ATPase PulE-like; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (494 aa)
pulDType II secretory pathway, component PulD. (708 aa)
pulCType II secretory pathway, component PulC. (291 aa)
IL2028Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit; Belongs to the HSP15 family. (133 aa)
hslORedox-responsive chaperonin Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. (274 aa)
IL21025-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (195 aa)
IL2132Uncharacterized conserved membrane protein, VanZ family. (110 aa)
IL2225Uncharacterized conserved secreted protein. (261 aa)
IL2274MerC-like membrane protein; Possibly involved in mercury resistance. (134 aa)
IL2278Uncharacterized conserved protein. (106 aa)
IL2279Uncharacterized conserved protein. (168 aa)
IL2294Uncharacterized conserved protein. (121 aa)
IL2295Probable lipoprotein. (331 aa)
comJTransformation competence-related protein ComJ; Specifically methylates the adenine in position 2030 of 23S rRNA. (283 aa)
IL2314OsmC-like predicted redox protein; Regulator of disulfide bond formation. (143 aa)
IL2315Uncharacterized conserved protein. (116 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (489 aa)
IL2317Arginine N-succinyltransferase. (340 aa)
IL2319Predicted glycosyltransferase. (234 aa)
IL2320Predicted HD-hydrolase family enzyme. (390 aa)
IL2345Uncharacterized conserved secreted protein. (167 aa)
IL2428Secreted protein related to cyanophycinase CphE. (558 aa)
IL2439Hemolysin III-like protein; Predicted membrane protein. (222 aa)
IL2440Uncharacterized conserved protein. (93 aa)
acrRAcrAB operon repressor. (204 aa)
metJTranscriptional regulator of met regulon (repressor); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. (107 aa)
dsbAProbable disulfide isomerase. (204 aa)
Your Current Organism:
Idiomarina loihiensis
NCBI taxonomy Id: 283942
Other names: I. loihiensis L2TR, Idiomarina loihiensis L2TR, Idiomarina loihiensis str. L2TR, Idiomarina loihiensis strain L2TR
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