STRINGSTRING
rpl39e rpl39e rpl31e rpl31e eif6 eif6 rpl18a rpl18a ftsY ftsY srp54 srp54 prf1 prf1 argS argS rps19e rps19e SDW05185.1 SDW05185.1 SDW05213.1 SDW05213.1 hisS hisS pan pan infB infB SDW05879.1 SDW05879.1 SDW06710.1 SDW06710.1 SDW06753.1 SDW06753.1 SDW06780.1 SDW06780.1 SDW06831.1 SDW06831.1 SDW08397.1 SDW08397.1 dnaJ dnaJ dnaK dnaK grpE grpE truB truB cmk cmk gatD gatD thrS thrS nop10 nop10 eif2a eif2a rps27e rps27e rpl44e rpl44e pan-2 pan-2 gatE gatE SDW16011.1 SDW16011.1 srp19 srp19 SDW24493.1 SDW24493.1 rpl10e rpl10e SDW26901.1 SDW26901.1 engB engB rps10 rps10 tuf tuf SDW27136.1 SDW27136.1 fusA fusA rps7 rps7 rps12 rps12 SDW27911.1 SDW27911.1 eif1a eif1a SDW28512.1 SDW28512.1 SDW28587.1 SDW28587.1 rps24e rps24e rps27ae rps27ae alaS alaS ileS ileS SDW32575.1 SDW32575.1 rps6e rps6e SDW40626.1 SDW40626.1 SDW40648.1 SDW40648.1 eif5a eif5a SDW43652.1 SDW43652.1 SDW38652.1 SDW38652.1 rpl15e rpl15e secE secE rps10-2 rps10-2 glpK glpK flpA flpA SDW50418.1 SDW50418.1 SDW50698.1 SDW50698.1 SDW51098.1 SDW51098.1 SDW51338.1 SDW51338.1 secY secY rpl15 rpl15 SDW63642.1 SDW63642.1 rpl30 rpl30 valS valS rps5 rps5 rpl18 rpl18 truD truD rpl19e rpl19e psmB psmB psmA psmA rpl32e rpl32e rpl6 rpl6 metG metG rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rps19p rps19p rpl2 rpl2 rpl23 rpl23 rpl4 rpl4 rpl3 rpl3 SDW61213.1 SDW61213.1 SDW61350.1 SDW61350.1 gatB gatB aspS aspS rpl37ae rpl37ae proS proS SDW74097.1 SDW74097.1 rps17e rps17e rps13 rps13 rps4 rps4 rps11 rps11 rpl21e rpl21e ef1b ef1b SDW76565.1 SDW76565.1 rpl18e rpl18e rpl13 rpl13 rps9 rps9 SDW77417.1 SDW77417.1 rps2 rps2 gltX gltX tmcA tmcA rpl7ae rpl7ae rps28e rps28e rpl24e rpl24e ndk ndk SDW73198.1 SDW73198.1 eif2g eif2g SDW82526.1 SDW82526.1 rlmE rlmE trm1 trm1 rpl40e rpl40e serS serS SDW87485.1 SDW87485.1 eif2b eif2b psmA-2 psmA-2 SDW90519.1 SDW90519.1 SDW94313.1 SDW94313.1 tyrS tyrS SDW95241.1 SDW95241.1 pelA pelA SDW98896.1 SDW98896.1 rps3ae rps3ae rps15 rps15 rps8e rps8e SDX03923.1 SDX03923.1 rpl12 rpl12 rpl10 rpl10 SDX09208.1 SDX09208.1 rpl1 rpl1 rpl11 rpl11 gatC gatC gatA gatA SDX08691.1 SDX08691.1 SDX17539.1 SDX17539.1 SDX17786.1 SDX17786.1 SDX17807.1 SDX17807.1 SDX18540.1 SDX18540.1 trpS trpS SDX18924.1 SDX18924.1 pheT pheT eif1a-2 eif1a-2 psmB-2 psmB-2 SDX38570.1 SDX38570.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rpl39eLSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa)
rpl31eLarge subunit ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (92 aa)
eif6Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (210 aa)
rpl18aLarge subunit ribosomal protein LX. (57 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (429 aa)
srp54Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (469 aa)
prf1Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (418 aa)
argSarginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (579 aa)
rps19eSSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa)
SDW05185.1DNA-binding TFAR19-related protein; Belongs to the PDCD5 family. (114 aa)
SDW05213.1Hypothetical protein. (205 aa)
hisShistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (435 aa)
panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (406 aa)
infBTranslation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (601 aa)
SDW05879.1UPF0271 protein. (152 aa)
SDW06710.1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase. (777 aa)
SDW06753.1Nucleoside-diphosphate-sugar epimerase. (331 aa)
SDW06780.1Nucleoside-diphosphate-sugar epimerase. (310 aa)
SDW06831.1UDP-sulfoquinovose synthase. (390 aa)
SDW08397.1Peptidyl-prolyl cis-trans isomerase A (cyclophilin A)/peptidyl-prolyl cis-trans isomerase B (cyclophilin B). (182 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (383 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone. (634 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (228 aa)
truBtRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (296 aa)
cmkCytidylate kinase. (192 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (415 aa)
thrSSer-tRNA(Thr) hydrolase /threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (642 aa)
nop10H/ACA ribonucleoprotein complex subunit 3; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (60 aa)
eif2aTranslation initiation factor 2 subunit alpha (aeIF-2a); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (266 aa)
rps27eSSU ribosomal protein S27E. (57 aa)
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (92 aa)
pan-2Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (404 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (623 aa)
SDW16011.1snoRNP protein GAR1. (75 aa)
srp19Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (100 aa)
SDW24493.1Hypothetical protein. (190 aa)
rpl10eLSU ribosomal protein L10AE; Belongs to the universal ribosomal protein uL16 family. (170 aa)
SDW26901.1Nucleolar GTP-binding protein. (331 aa)
engBSmall GTP-binding protein domain-containing protein; Necessary for normal cell division and for the maintenance of normal septation. (205 aa)
rps10SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (421 aa)
SDW27136.1STE24 endopeptidase. (364 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (728 aa)
rps7SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (206 aa)
rps12SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
SDW27911.1Translation initiation factor 1 (eIF-1/SUI1); Belongs to the SUI1 family. (97 aa)
eif1aTranslation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (95 aa)
SDW28512.1RIO kinase 1. (311 aa)
SDW28587.1Ribosomal RNA assembly protein. (182 aa)
rps24eSSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (102 aa)
rps27aeSSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (927 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1074 aa)
SDW32575.1leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (892 aa)
rps6eSSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (129 aa)
SDW40626.1Serine/threonine protein kinase. (302 aa)
SDW40648.1DolP-mannose mannosyltransferase. (410 aa)
eif5aTranslation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (126 aa)
SDW43652.1Lon-like ATP-dependent protease; Belongs to the peptidase S16 family. (709 aa)
SDW38652.1ATP-binding cassette, sub-family E, member 1. (609 aa)
rpl15eLSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa)
rps10-2SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (110 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (510 aa)
flpArRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (210 aa)
SDW50418.1rRNA biogenesis protein Nop56/Nop58. (280 aa)
SDW50698.1Phospholipid-binding protein, PBP family. (151 aa)
SDW51098.1DnaJ domain-containing protein. (317 aa)
SDW51338.1Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (487 aa)
rpl15LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (165 aa)
SDW63642.1tRNA-binding protein. (114 aa)
rpl30LSU ribosomal protein L30P. (154 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (919 aa)
rps5SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa)
rpl18LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (187 aa)
truDtRNA pseudouridine13 synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (460 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
psmBProteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (230 aa)
psmAProteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (244 aa)
rpl32eLSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (241 aa)
rpl6LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (732 aa)
rps8SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps14SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (61 aa)
rpl5LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (177 aa)
rps4eSSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (251 aa)
rpl24LSU ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (120 aa)
rpl14LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rps17SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (117 aa)
rpl29LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rps3SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (304 aa)
rpl22LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (155 aa)
rps19pSSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl2LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (240 aa)
rpl23LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (85 aa)
rpl4LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (246 aa)
rpl3LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (327 aa)
SDW61213.1Hypothetical protein. (281 aa)
SDW61350.1Translation elongation factor 1A GTP binding domain family. (543 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (504 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (480 aa)
rpl37aeLSU ribosomal protein L37AE; Binds to the 23S rRNA. (116 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (484 aa)
SDW74097.1Nucleoside-diphosphate-sugar epimerase. (327 aa)
rps17eSSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa)
rps13SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (177 aa)
rps4SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (171 aa)
rps11SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpl21eLSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa)
ef1bTranslation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
SDW76565.1Hypothetical protein. (59 aa)
rpl18eLSU ribosomal protein L18AE; Belongs to the eukaryotic ribosomal protein eL18 family. (116 aa)
rpl13LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (145 aa)
rps9SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (132 aa)
SDW77417.1Serine protease, S1-C subfamily, contains C-terminal PDZ domain. (361 aa)
rps2SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (273 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (579 aa)
tmcAtRNA(Met) cytidine acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (745 aa)
rpl7aeLSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
rps28eSSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (75 aa)
rpl24eLSU ribosomal protein L24E; Binds to the 23S rRNA. (117 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa)
SDW73198.1Translation initiation factor 2 subunit beta (aeIF-2b). (203 aa)
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (409 aa)
SDW82526.1SSU processome protein Utp24. (125 aa)
rlmE23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (263 aa)
trm1N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (367 aa)
rpl40eLSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (460 aa)
SDW87485.1SSU ribosomal protein S17E. (65 aa)
eif2bTranslation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (134 aa)
psmA-2Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (258 aa)
SDW90519.1Ribosome maturation protein SDO1. (242 aa)
SDW94313.1DnaJ domain-containing protein. (219 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (346 aa)
SDW95241.1alanyl-tRNA synthetase. (414 aa)
pelACell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (355 aa)
SDW98896.1Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains. (717 aa)
rps3aeSSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (213 aa)
rps15SSU ribosomal protein S15P. (153 aa)
rps8eSSU ribosomal protein S8E. (123 aa)
SDX03923.1Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN metalloenzyme (JAMM) motif. (165 aa)
rpl12LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa)
rpl10LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (348 aa)
SDX09208.1Hypothetical protein. (282 aa)
rpl1LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
rpl11LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (162 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (92 aa)
gatAaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (444 aa)
SDX08691.1Hypothetical protein. (369 aa)
SDX17539.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (565 aa)
SDX17786.1Nonsense-mediated mRNA decay protein 3. (378 aa)
SDX17807.1Nucleoside-diphosphate-sugar epimerase. (297 aa)
SDX18540.1leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (892 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (549 aa)
SDX18924.1phenylalanyl-tRNA synthetase, alpha subunit. (503 aa)
pheTphenylalanyl-tRNA synthetase beta subunit. (583 aa)
eif1a-2Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (87 aa)
psmB-2Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (240 aa)
SDX38570.1Serine protease, S1-C subfamily, contains C-terminal PDZ domain. (363 aa)
Your Current Organism:
Haloarcula vallismortis
NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54
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