STRINGSTRING
tbp tbp tfe tfe rad25 rad25 SDW93515.1 SDW93515.1 tfb-6 tfb-6 SDX17730.1 SDX17730.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tbpTATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (186 aa)
tfeTranscription factor E (TFE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. [...] (176 aa)
rad25DNA excision repair protein ERCC-3. (621 aa)
SDW93515.1DNA-directed RNA polymerase, subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa)
tfb-6Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (324 aa)
SDX17730.1Rad3-related DNA helicase. (575 aa)
Your Current Organism:
Haloarcula vallismortis
NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54
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