STRINGSTRING
SDX14122.1 SDX14122.1 SDX08691.1 SDX08691.1 ureG ureG SDX07061.1 SDX07061.1 SDX02111.1 SDX02111.1 SDW99920.1 SDW99920.1 SDW98658.1 SDW98658.1 SDW98241.1 SDW98241.1 SDW95538.1 SDW95538.1 SDW94867.1 SDW94867.1 SDW91362.1 SDW91362.1 SDW91151.1 SDW91151.1 SDW90648.1 SDW90648.1 SDW89732.1 SDW89732.1 SDW89365.1 SDW89365.1 SDW79977.1 SDW79977.1 hel308 hel308 eif2g eif2g SDW82327.1 SDW82327.1 SDW71864.1 SDW71864.1 SDW77697.1 SDW77697.1 SDW77471.1 SDW77471.1 SDW76729.1 SDW76729.1 SDW71183.1 SDW71183.1 rad25 rad25 smc smc SDW61350.1 SDW61350.1 SDW67382.1 SDW67382.1 SDW66761.1 SDW66761.1 rad50 rad50 SDW65813.1 SDW65813.1 SDW65223.1 SDW65223.1 rfcL rfcL SDW63118.1 SDW63118.1 SDW51880.1 SDW51880.1 SDW51549.1 SDW51549.1 SDW55720.1 SDW55720.1 SDW55296.1 SDW55296.1 SDW55244.1 SDW55244.1 ftsZ-2 ftsZ-2 SDW52281.1 SDW52281.1 uvrA uvrA SDW45941.1 SDW45941.1 SDW38063.1 SDW38063.1 SDW42837.1 SDW42837.1 ftsZ ftsZ SDW40806.1 SDW40806.1 SDW31683.1 SDW31683.1 SDW31271.1 SDW31271.1 rfcS rfcS mutL mutL SDW28885.1 SDW28885.1 SDW27840.1 SDW27840.1 fusA fusA tuf tuf SDW26901.1 SDW26901.1 hisE hisE SDW21407.1 SDW21407.1 SDW02401.1 SDW02401.1 pan-2 pan-2 guaAB guaAB cetZ-2 cetZ-2 ppa ppa cetZ cetZ SDW06172.1 SDW06172.1 uvrB uvrB infB infB pan pan srp54 srp54 ftsY ftsY SDX33784.1 SDX33784.1 SDX33616.1 SDX33616.1 cetZ-3 cetZ-3 SDX27991.1 SDX27991.1 SDX21974.1 SDX21974.1 SDX21658.1 SDX21658.1 SDX18393.1 SDX18393.1 SDX17730.1 SDX17730.1 SDX17539.1 SDX17539.1 SDX15983.1 SDX15983.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDX14122.1Cd2+/Zn2+-exporting ATPase. (806 aa)
SDX08691.1Hypothetical protein. (369 aa)
ureGUrease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (207 aa)
SDX07061.1Ca2+-transporting ATPase. (861 aa)
SDX02111.1Transitional endoplasmic reticulum ATPase. (741 aa)
SDW99920.1MoxR-like ATPase. (336 aa)
SDW98658.1ATP dependent helicase, Lhr family. (916 aa)
SDW98241.1LAO/AO transport system kinase. (352 aa)
SDW95538.1Cu+-exporting ATPase. (868 aa)
SDW94867.1Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (168 aa)
SDW91362.1ATP dependent helicase, Lhr family. (944 aa)
SDW91151.1Cu2+-exporting ATPase. (793 aa)
SDW90648.1Acylphosphatase. (91 aa)
SDW89732.1ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (412 aa)
SDW89365.1MoxR-like ATPase. (313 aa)
SDW79977.1DNA excision repair protein ERCC-2. (725 aa)
hel308Helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (800 aa)
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (409 aa)
SDW82327.1Membrane protease FtsH catalytic subunit; Belongs to the AAA ATPase family. (449 aa)
SDW71864.1Arsenite efflux ATP-binding protein ArsA. (313 aa)
SDW77697.1Putative membrane protein. (336 aa)
SDW77471.1Cd2+/Zn2+-exporting ATPase. (859 aa)
SDW76729.1GTP-binding conserved hypothetical protein TIGR00650. (393 aa)
SDW71183.1ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (353 aa)
rad25DNA excision repair protein ERCC-3. (621 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1195 aa)
SDW61350.1Translation elongation factor 1A GTP binding domain family. (543 aa)
SDW67382.1GTP-binding conserved hypothetical protein TIGR00650. (395 aa)
SDW66761.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (206 aa)
rad50Exonuclease SbcC; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily. (891 aa)
SDW65813.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (519 aa)
SDW65223.1AAA+-type ATPase, SpoVK/Ycf46/Vps4 family. (846 aa)
rfcLReplication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (503 aa)
SDW63118.1MoxR-like ATPase. (315 aa)
SDW51880.1Transitional endoplasmic reticulum ATPase. (706 aa)
SDW51549.1Competence/damage-inducible protein cinA. (231 aa)
SDW55720.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (142 aa)
SDW55296.1Arsenite efflux ATP-binding protein ArsA. (362 aa)
SDW55244.1DNA excision repair protein ERCC-2. (815 aa)
ftsZ-2Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (386 aa)
SDW52281.1Transitional endoplasmic reticulum ATPase. (757 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (993 aa)
SDW45941.1Phage/plasmid primase, P4 family, C-terminal domain-containing protein. (575 aa)
SDW38063.1MoxR-like ATPase. (327 aa)
SDW42837.1PAP2 superfamily protein. (268 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (413 aa)
SDW40806.1Transitional endoplasmic reticulum ATPase. (695 aa)
SDW31683.1Molybdenum cofactor synthesis domain-containing protein. (246 aa)
SDW31271.1Arsenite efflux ATP-binding protein ArsA. (324 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (325 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (717 aa)
SDW28885.1dITPase. (223 aa)
SDW27840.1MoxR-like ATPase. (319 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (728 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (421 aa)
SDW26901.1Nucleolar GTP-binding protein. (331 aa)
hisEphosphoribosyl-ATP pyrophosphatase. (98 aa)
SDW21407.1dUTP pyrophosphatase. (153 aa)
SDW02401.1MoxR-like ATPase. (317 aa)
pan-2Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (404 aa)
guaABGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (305 aa)
cetZ-2Cell division GTPase FtsZ; Involved in cell shape control; Belongs to the CetZ family. (357 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (177 aa)
cetZCell division GTPase FtsZ; Involved in cell shape control; Belongs to the CetZ family. (393 aa)
SDW06172.1Undecaprenyl-diphosphatase. (270 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (686 aa)
infBTranslation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (601 aa)
panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (406 aa)
srp54Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (469 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (429 aa)
SDX33784.1Arsenite efflux ATP-binding protein ArsA. (641 aa)
SDX33616.1ATP-dependent helicase/nuclease subunit A. (1168 aa)
cetZ-3Cell division GTPase FtsZ; Involved in cell shape control; Belongs to the CetZ family. (368 aa)
SDX27991.1Hypothetical protein. (365 aa)
SDX21974.1ATP-dependent helicase/nuclease subunit A. (1211 aa)
SDX21658.15-methylcytosine-specific restriction enzyme B. (410 aa)
SDX18393.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (559 aa)
SDX17730.1Rad3-related DNA helicase. (575 aa)
SDX17539.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (565 aa)
SDX15983.1Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family. (541 aa)
Your Current Organism:
Haloarcula vallismortis
NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54
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