STRINGSTRING
SDX02696.1 SDX02696.1 SDX15983.1 SDX15983.1 SDX17539.1 SDX17539.1 SDX18393.1 SDX18393.1 SDX25604.1 SDX25604.1 dnaK dnaK grpE grpE SDW31327.1 SDW31327.1 SDW33783.1 SDW33783.1 fau-1 fau-1 SDW39450.1 SDW39450.1 SDW52113.1 SDW52113.1 SDW65813.1 SDW65813.1 SDW65977.1 SDW65977.1 SDW75005.1 SDW75005.1 eno eno rnj rnj SDW82216.1 SDW82216.1 ppk ppk SDW90853.1 SDW90853.1 SDW90882.1 SDW90882.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDX02696.1TIGR00288 family protein. (148 aa)
SDX15983.1Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family. (541 aa)
SDX17539.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (565 aa)
SDX18393.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (559 aa)
SDX25604.12-(3-amino-3-carboxypropyl)histidine synthase; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (348 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone. (634 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (228 aa)
SDW31327.1GTPase, G3E family. (433 aa)
SDW33783.1Hypothetical protein. (228 aa)
fau-1RNA-binding protein AU-1; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (466 aa)
SDW39450.1Ribonuclease R. (457 aa)
SDW52113.1Small nuclear ribonucleoprotein, LSM family. (60 aa)
SDW65813.1Thermosome subunit; Belongs to the TCP-1 chaperonin family. (519 aa)
SDW65977.1Uncharacterized protein. (238 aa)
SDW75005.1Uncharacterized conserved protein, LabA/DUF88 family. (165 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (458 aa)
SDW82216.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (155 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (837 aa)
SDW90853.1Ca-activated chloride channel family protein. (394 aa)
SDW90882.1Protein kinase/serine/threonine protein kinase. (412 aa)
Your Current Organism:
Haloarcula vallismortis
NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54
Server load: low (20%) [HD]