(5 nodes) Mixed, incl. RIO kinase, and AARP2CN (NUC121) domain network (Kluyveromyces lactis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KLLA0_F16280g	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (472 aa)
	KLLA0_F06622g	KLLA0F06622p. (478 aa)
	KLLA0_E05149g	KLLA0E05149p. (787 aa)
	KLLA0_D19008g	KLLA0D19008p. (422 aa)
	PNO1	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity). (274 aa)

Your Current Organism:

Kluyveromyces lactis

NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KLLA0_D19008g	KLLA0_E05149g	Q6CQ85	Q6CPG2	KLLA0D19008p.	KLLA0E05149p.	0.998
KLLA0_D19008g	KLLA0_F06622g	Q6CQ85	Q6CL09	KLLA0D19008p.	KLLA0F06622p.	0.995
KLLA0_D19008g	KLLA0_F16280g	Q6CQ85	Q6CJS6	KLLA0D19008p.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.999
KLLA0_D19008g	PNO1	Q6CQ85	Q6CUA5	KLLA0D19008p.	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	0.998
KLLA0_E05149g	KLLA0_D19008g	Q6CPG2	Q6CQ85	KLLA0E05149p.	KLLA0D19008p.	0.998
KLLA0_E05149g	KLLA0_F06622g	Q6CPG2	Q6CL09	KLLA0E05149p.	KLLA0F06622p.	0.999
KLLA0_E05149g	KLLA0_F16280g	Q6CPG2	Q6CJS6	KLLA0E05149p.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.999
KLLA0_E05149g	PNO1	Q6CPG2	Q6CUA5	KLLA0E05149p.	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	0.996
KLLA0_F06622g	KLLA0_D19008g	Q6CL09	Q6CQ85	KLLA0F06622p.	KLLA0D19008p.	0.995
KLLA0_F06622g	KLLA0_E05149g	Q6CL09	Q6CPG2	KLLA0F06622p.	KLLA0E05149p.	0.999
KLLA0_F06622g	KLLA0_F16280g	Q6CL09	Q6CJS6	KLLA0F06622p.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.999
KLLA0_F06622g	PNO1	Q6CL09	Q6CUA5	KLLA0F06622p.	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	0.999
KLLA0_F16280g	KLLA0_D19008g	Q6CJS6	Q6CQ85	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	KLLA0D19008p.	0.999
KLLA0_F16280g	KLLA0_E05149g	Q6CJS6	Q6CPG2	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	KLLA0E05149p.	0.999
KLLA0_F16280g	KLLA0_F06622g	Q6CJS6	Q6CL09	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	KLLA0F06622p.	0.999
KLLA0_F16280g	PNO1	Q6CJS6	Q6CUA5	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	0.999
PNO1	KLLA0_D19008g	Q6CUA5	Q6CQ85	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	KLLA0D19008p.	0.998
PNO1	KLLA0_E05149g	Q6CUA5	Q6CPG2	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	KLLA0E05149p.	0.996
PNO1	KLLA0_F06622g	Q6CUA5	Q6CL09	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	KLLA0F06622p.	0.999
PNO1	KLLA0_F16280g	Q6CUA5	Q6CJS6	Pre-rRNA-processing protein PNO1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.999