Your Input: | |
| | KLLA0_D03674g | KLLA0D03674p. (453 aa) |
| | RGR1 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (998 aa) |
| | KLLA0_D06699g | KLLA0D06699p. (70 aa) |
| | KLLA0_D06765g | KLLA0D06765p. (473 aa) |
| | KLLA0_D06831g | KLLA0D06831p. (256 aa) |
| | KLLA0_D07139g | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa) |
| | KLLA0_D08008g | KLLA0D08008p. (70 aa) |
| | KLLA0_D09625g | KLLA0D09625p. (245 aa) |
| | KLLA0_D10219g | KLLA0D10219p. (159 aa) |
| | KLLA0_D10461g | KLLA0D10461p. (564 aa) |
| | BUR1 | Serine/threonine-protein kinase BUR1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (645 aa) |
| | SRB4 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (671 aa) |
| | KLLA0_D12408g | KLLA0D12408p. (184 aa) |
| | SRB5 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (255 aa) |
| | SRB6 | Mediator of RNA polymerase II transcription subunit 22; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (121 aa) |
| | KLLA0_D16170g | KLLA0D16170p. (307 aa) |
| | KLLA0_D16368g | KLLA0D16368p. (511 aa) |
| | KLLA0_D17204g | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (192 aa) |
| | KLLA0_D18029g | KLLA0D18029p. (244 aa) |
| | KLLA0_D18689g | KLLA0D18689p. (465 aa) |
| | RTT106 | Histone chaperone RTT106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (459 aa) |
| | SSU72 | RNA polymerase II subunit A C-terminal domain phosphatase SSU72; Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1); Belongs to the SSU72 phosphatase family. (207 aa) |
| | KLLA0_D19646g | KLLA0D19646p. (314 aa) |
| | SIN4 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (956 aa) |
| | KLLA0_E01915g | KLLA0E01915p. (1073 aa) |
| | KLLA0_E01981g | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa) |
| | KLLA0_C13167g | KLLA0C13167p. (339 aa) |
| | KLLA0_E14785g | KLLA0E14785p. (310 aa) |
| | SPT3 | Protein SPT3; SPT factors 3, 7 and 8 are required for the initiation of Ty transcription from the delta promoter. SPT3 regulates Ty1 as well as the mating factor genes. Interacts directly with TATA-binding protein. It is likely to be required for normal TBP function at a subset of RNA polymerase II-dependent promoters. (328 aa) |
| | GAL11 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required [...] (1034 aa) |
| | SUA7 | Transcription initiation factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. (357 aa) |
| | KLLA0_F27291g | KLLA0F27291p. (349 aa) |
| | KLLA0_F25828g | KLLA0F25828p. (623 aa) |
| | KLLA0_F25003g | KLLA0F25003p. (132 aa) |
| | KLLA0_F24838g | KLLA0F24838p. (1062 aa) |
| | DBP2 | ATP-dependent RNA helicase DBP2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (554 aa) |
| | KLLA0_F23353g | KLLA0F23353p. (281 aa) |
| | KLLA0_F21868g | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (171 aa) |
| | RPB5 | DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower [...] (215 aa) |
| | KLLA0_F20526g | KLLA0F20526p. (414 aa) |
| | KLLA0_F20361g | KLLA0F20361p. (447 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (285 aa) |
| | KLLA0_F17523g | KLLA0F17523p. (855 aa) |
| | KLLA0_F17413g | KLLA0F17413p. (502 aa) |
| | CCR4 | Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (790 aa) |
| | KLLA0_F15411g | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (686 aa) |
| | KLLA0_F14487g | KLLA0F14487p. (302 aa) |
| | KLLA0_F13728g | KLLA0F13728p. (420 aa) |
| | KLLA0_F13442g | KLLA0F13442p. (587 aa) |
| | BUR2 | Protein BUR2; Component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates the UBC2/RAD6 ubiquitin- conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone- induced growth arrest in the cell cycle G1 phase. The kinase activity of the complex requires the presence of BUR2. Overexpression of BUR2 interferes with mitotic chromosome segregation (By similarity). (394 aa) |
| | KLLA0_F10659g | KLLA0F10659p. (516 aa) |
| | KLLA0_F09361g | KLLA0F09361p. (292 aa) |
| | RAT1 | 5'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity); Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (992 aa) |
| | KLLA0_F06710g | KLLA0F06710p. (1096 aa) |
| | CSE2 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (123 aa) |
| | KLLA0_F05071g | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1720 aa) |
| | KLLA0_F04521g | KLLA0F04521p. (1344 aa) |
| | KLLA0_F02387g | KLLA0F02387p. (727 aa) |
| | KLLA0_F01925g | KLLA0F01925p. (428 aa) |
| | TFB2 | General transcription and DNA repair factor IIH subunit TFB2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...] (496 aa) |
| | KLLA0_F00748g | KLLA0F00748p. (229 aa) |
| | MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (215 aa) |
| | KLLA0_E23453g | KLLA0E23453p. (826 aa) |
| | SUB2 | ATP-dependent RNA helicase SUB2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (437 aa) |
| | HIR2 | Protein HIR2; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (847 aa) |
| | KLLA0_E19229g | KLLA0E19229p. (739 aa) |
| | KLLA0_E18657g | KLLA0E18657p. (530 aa) |
| | KLLA0_E18195g | KLLA0E18195p. (1133 aa) |
| | KLLA0_E16567g | Peptidyl-prolyl cis-trans isomerase. (162 aa) |
| | EAF3 | Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (358 aa) |
| | KLLA0_E13025g | KLLA0E13025p. (858 aa) |
| | RAI1 | Decapping nuclease RAI1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (384 aa) |
| | KLLA0_E10099g | KLLA0E10099p. (233 aa) |
| | KLLA0_E09615g | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (488 aa) |
| | INO80 | Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1489 aa) |
| | NUT1 | Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1067 aa) |
| | MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (213 aa) |
| | ROX3 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (206 aa) |
| | KLLA0_E06689g | KLLA0E06689p; Belongs to the cyclin family. (398 aa) |
| | KLLA0_E06315g | KLLA0E06315p; Belongs to the actin family. (438 aa) |
| | KLLA0_E04137g | KLLA0E04137p. (552 aa) |
| | KLLA0_E02311g | KLLA0E02311p. (417 aa) |
| | KLLA0_E02047g | KLLA0E02047p. (730 aa) |
| | KLLA0_B05555g | KLLA0B05555p. (1997 aa) |
| | KLLA0_B05577g | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1221 aa) |
| | KLLA0_B08305g | KLLA0B08305p. (735 aa) |
| | TFB4 | General transcription and DNA repair factor IIH subunit TFB4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...] (337 aa) |
| | KLLA0_B09196g | KLLA0B09196p. (590 aa) |
| | SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of [...] (96 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (426 aa) |
| | KLLA0_B10351g | KLLA0B10351p. (432 aa) |
| | KLLA0_B10472g | Nuclear cap-binding protein subunit 2. (198 aa) |
| | NUT2 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (161 aa) |
| | SPT6 | Transcription elongation factor SPT6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1460 aa) |
| | KLLA0_B13211g | KLLA0B13211p. (915 aa) |
| | KLLA0_C00913g | KLLA0C00913p. (474 aa) |
| | KLLA0_C02189g | KLLA0C02189p. (1380 aa) |
| | KLLA0_C02893g | KLLA0C02893p. (623 aa) |
| | YSH1 | Endoribonuclease YSH1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily. (764 aa) |
| | UBC2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (164 aa) |
| | KLLA0_C05676g | KLLA0C05676p. (511 aa) |
| | SOH1 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (124 aa) |
| | TAF4 | Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...] (366 aa) |
| | KLLA0_C06116g | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (785 aa) |
| | KLLA0_C06160g | KLLA0C06160p. (121 aa) |
| | KLLA0_C06611g | KLLA0C06611p. (153 aa) |
| | KLLA0_C06787g | KLLA0C06787p. (171 aa) |
| | MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (268 aa) |
| | CFT1 | Protein CFT1; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation- dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity); Belongs to the CFT1 family. (1300 aa) |
| | SRB2 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (211 aa) |
| | TFB5 | General transcription and DNA repair factor IIH subunit TFB5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...] (72 aa) |
| | KLLA0_C11935g | KLLA0C11935p. (150 aa) |
| | KLLA0_C12507g | KLLA0C12507p; Belongs to the actin family. (454 aa) |
| | KLLA0_C12815g | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (113 aa) |
| | KLLA0_C14630g | KLLA0C14630p. (620 aa) |
| | SRB7 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (143 aa) |
| | TFB3 | RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity). (318 aa) |
| | KLLA0_C17578g | KLLA0C17578p. (1525 aa) |
| | KLLA0_C17776g | KLLA0C17776p. (778 aa) |
| | KLLA0_C18194g | KLLA0C18194p. (388 aa) |
| | SFH1 | Chromatin structure-remodeling complex subunit SFH1; Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome [...] (442 aa) |
| | KLLA0_C18612g | KLLA0C18612p. (2140 aa) |
| | KLLA0_C18821g | KLLA0C18821p. (447 aa) |
| | KLLA0_D03036g | KLLA0D03036p. (368 aa) |
| | KLLA0_D03234g | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa) |
| | KLLA0_A00737g | KLLA0A00737p. (582 aa) |
| | KLLA0_A02959g | KLLA0A02959p. (559 aa) |
| | KLLA0_A03663g | KLLA0A03663p. (824 aa) |
| | HIR1 | Protein HIR1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (861 aa) |
| | KLLA0_A05247g | KLLA0A05247p. (259 aa) |
| | KLLA0_A05797g | KLLA0A05797p. (200 aa) |
| | KLLA0_A05951g | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (286 aa) |
| | SET2 | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (702 aa) |
| | KLLA0_A09251g | KLLA0A09251p. (688 aa) |
| | KLLA0_A09427g | KLLA0A09427p. (1011 aa) |
| | KLLA0_A10021g | KLLA0A10021p. (1033 aa) |
| | KLLA0_A10219g | KLLA0A10219p. (475 aa) |
| | KLLA0_A11594g | KLLA0A11594p. (1530 aa) |
| | KLLA0_B01067g | KLLA0B01067p. (350 aa) |
| | BRE1 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. (663 aa) |
| | KLLA0_B03476g | KLLA0B03476p. (158 aa) |
| | HIR3 | Histone transcription regulator 3 homolog; Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation. Belongs to the HIR3 family. (1651 aa) |
